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CATH Superfamily 1.20.1530.20

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Glutathione-regulated potassium-efflux system prot...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Glutathione-regulated potassium exporter activity GO:0015503
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(in) + H+(out) = K+(out) + H+(in), where glutathione maintains the closed state.
 16 P03819 (/IMP) P03819 (/IMP) P03819 (/IMP) P03819 (/IMP) P03819 (/IMP) P03819 (/IMP) P03819 (/IMP) P03819 (/IMP) P03819 (/IMP) P03819 (/IMP)
(6 more)
Toxic substance binding GO:0015643
Interacting selectively and non-covalently with a toxic substance, a poisonous substance that causes damage to biological systems.
 16 P03819 (/IDA) P03819 (/IDA) P03819 (/IDA) P03819 (/IDA) P03819 (/IDA) P03819 (/IDA) P03819 (/IDA) P03819 (/IDA) P03819 (/IDA) P03819 (/IDA)
(6 more)
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
 16 P03819 (/IMP) P03819 (/IMP) P03819 (/IMP) P03819 (/IMP) P03819 (/IMP) P03819 (/IMP) P03819 (/IMP) P03819 (/IMP) P03819 (/IMP) P03819 (/IMP)
(6 more)
Glutathione-regulated potassium exporter activity GO:0015503
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(in) + H+(out) = K+(out) + H+(in), where glutathione maintains the closed state.
 14 Q48JU4 (/ISS) Q48JU4 (/ISS) Q48JU4 (/ISS) Q5LTJ0 (/ISS) Q87XC4 (/ISS) Q87XC4 (/ISS) Q883K2 (/ISS) Q883K2 (/ISS) Q883K2 (/ISS) Q883K2 (/ISS)
(4 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
 1 Q7NKY3 (/IPI)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Potassium ion transport GO:0006813
The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
 17 P45522 (/IGI) P45522 (/IGI) P45522 (/IGI) P45522 (/IGI) P45522 (/IGI) P45522 (/IGI) P45522 (/IGI) P45522 (/IGI) P45522 (/IGI) P45522 (/IGI)
(7 more)
Potassium ion transport GO:0006813
The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
 16 P03819 (/IDA) P03819 (/IDA) P03819 (/IDA) P03819 (/IDA) P03819 (/IDA) P03819 (/IDA) P03819 (/IDA) P03819 (/IDA) P03819 (/IDA) P03819 (/IDA)
(6 more)
Regulation of pH GO:0006885
Any process involved in the maintenance of an internal equilibrium of hydrogen ions, thereby modulating the internal pH, within an organism or cell.
 16 P03819 (/IDA) P03819 (/IDA) P03819 (/IDA) P03819 (/IDA) P03819 (/IDA) P03819 (/IDA) P03819 (/IDA) P03819 (/IDA) P03819 (/IDA) P03819 (/IDA)
(6 more)
Response to toxic substance GO:0009636
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus.
 16 P03819 (/IMP) P03819 (/IMP) P03819 (/IMP) P03819 (/IMP) P03819 (/IMP) P03819 (/IMP) P03819 (/IMP) P03819 (/IMP) P03819 (/IMP) P03819 (/IMP)
(6 more)
Response to methylglyoxal GO:0051595
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylglyoxal stimulus. Methylglyoxal is a 2-oxoaldehyde derived from propanal.
 16 P03819 (/IMP) P03819 (/IMP) P03819 (/IMP) P03819 (/IMP) P03819 (/IMP) P03819 (/IMP) P03819 (/IMP) P03819 (/IMP) P03819 (/IMP) P03819 (/IMP)
(6 more)
Potassium ion transport GO:0006813
The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
 13 Q48JU4 (/ISS) Q48JU4 (/ISS) Q48JU4 (/ISS) Q87XC4 (/ISS) Q87XC4 (/ISS) Q883K2 (/ISS) Q883K2 (/ISS) Q883K2 (/ISS) Q883K2 (/ISS) Q8EGW0 (/ISS)
(3 more)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
 33 P03819 (/IDA) P03819 (/IDA) P03819 (/IDA) P03819 (/IDA) P03819 (/IDA) P03819 (/IDA) P03819 (/IDA) P03819 (/IDA) P03819 (/IDA) P03819 (/IDA)
(23 more)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
 16 P03819 (/EXP) P03819 (/EXP) P03819 (/EXP) P03819 (/EXP) P03819 (/EXP) P03819 (/EXP) P03819 (/EXP) P03819 (/EXP) P03819 (/EXP) P03819 (/EXP)
(6 more)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
 16 P03819 (/IDA) P03819 (/IDA) P03819 (/IDA) P03819 (/IDA) P03819 (/IDA) P03819 (/IDA) P03819 (/IDA) P03819 (/IDA) P03819 (/IDA) P03819 (/IDA)
(6 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
 16 P03819 (/IDA) P03819 (/IDA) P03819 (/IDA) P03819 (/IDA) P03819 (/IDA) P03819 (/IDA) P03819 (/IDA) P03819 (/IDA) P03819 (/IDA) P03819 (/IDA)
(6 more)
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