The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Na+/H+ antiporter like domain
".
FunFam 1: Na(+)/H(+) antiporter NhaA
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Sodium:proton antiporter activity GO:0015385
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + H+(in) = Na+(in) + H+(out).
|
9 | O85187 (/ISS) O85187 (/ISS) O85187 (/ISS) O85187 (/ISS) O85187 (/ISS) O85187 (/ISS) O85187 (/ISS) O85187 (/ISS) O85187 (/ISS) |
|
Sodium:proton antiporter activity GO:0015385
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + H+(in) = Na+(in) + H+(out).
|
6 | P13738 (/IDA) P13738 (/IDA) P13738 (/IDA) P13738 (/IDA) P13738 (/IDA) P13738 (/IDA) |
|
Cardiolipin binding GO:1901612
Interacting selectively and non-covalently with cardiolipin.
|
6 | P13738 (/IDA) P13738 (/IDA) P13738 (/IDA) P13738 (/IDA) P13738 (/IDA) P13738 (/IDA) |
There are 6 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Sodium ion transport GO:0006814
The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
9 | O85187 (/ISS) O85187 (/ISS) O85187 (/ISS) O85187 (/ISS) O85187 (/ISS) O85187 (/ISS) O85187 (/ISS) O85187 (/ISS) O85187 (/ISS) |
|
Proton transmembrane transport GO:1902600
The directed movement of a proton across a membrane.
|
9 | O85187 (/ISS) O85187 (/ISS) O85187 (/ISS) O85187 (/ISS) O85187 (/ISS) O85187 (/ISS) O85187 (/ISS) O85187 (/ISS) O85187 (/ISS) |
|
Cellular sodium ion homeostasis GO:0006883
Any process involved in the maintenance of an internal steady state of sodium ions at the level of a cell.
|
6 | P13738 (/IMP) P13738 (/IMP) P13738 (/IMP) P13738 (/IMP) P13738 (/IMP) P13738 (/IMP) |
|
Sodium ion export across plasma membrane GO:0036376
The directed movement of sodium ions from inside of a cell, across the plasma membrane and into the extracellular region.
|
6 | P13738 (/IDA) P13738 (/IDA) P13738 (/IDA) P13738 (/IDA) P13738 (/IDA) P13738 (/IDA) |
|
Response to cation stress GO:0043157
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cation stress, an increase or decrease in the concentration of positively charged ions in the environment.
|
6 | P13738 (/IEP) P13738 (/IEP) P13738 (/IEP) P13738 (/IEP) P13738 (/IEP) P13738 (/IEP) |
|
Regulation of intracellular pH GO:0051453
Any process that modulates the internal pH of a cell, measured by the concentration of the hydrogen ion.
|
6 | P13738 (/IDA) P13738 (/IDA) P13738 (/IDA) P13738 (/IDA) P13738 (/IDA) P13738 (/IDA) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
6 | P13738 (/IDA) P13738 (/IDA) P13738 (/IDA) P13738 (/IDA) P13738 (/IDA) P13738 (/IDA) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
6 | P13738 (/IDA) P13738 (/IDA) P13738 (/IDA) P13738 (/IDA) P13738 (/IDA) P13738 (/IDA) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
6 | P13738 (/ISM) P13738 (/ISM) P13738 (/ISM) P13738 (/ISM) P13738 (/ISM) P13738 (/ISM) |
