The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
subunit c (vma5p) of the yeast v-atpase, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4: V-type proton ATPase subunit C

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein dimerization activity GO:0046983
The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.
4 Q8NEY4 (/IDA) Q8NEY4 (/IDA) Q8NEY4 (/IDA) Q8NEY4 (/IDA)
Proton-exporting ATPase activity, phosphorylative mechanism GO:0008553
Enables the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) -> ADP + phosphate + H+(out). These transporters use a phosphorylative mechanism, which have a phosphorylated intermediate state during the ion transport cycle.
1 Q99L60 (/IDA)
Protein dimerization activity GO:0046983
The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.
1 Q99L60 (/ISO)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Insulin receptor signaling pathway GO:0008286
The series of molecular signals generated as a consequence of the insulin receptor binding to insulin.
4 Q8NEY4 (/TAS) Q8NEY4 (/TAS) Q8NEY4 (/TAS) Q8NEY4 (/TAS)
Regulation of macroautophagy GO:0016241
Any process that modulates the frequency, rate or extent of macroautophagy.
4 Q8NEY4 (/NAS) Q8NEY4 (/NAS) Q8NEY4 (/NAS) Q8NEY4 (/NAS)
Positive regulation of Wnt signaling pathway GO:0030177
Any process that activates or increases the frequency, rate or extent of Wnt signal transduction.
4 Q8NEY4 (/IMP) Q8NEY4 (/IMP) Q8NEY4 (/IMP) Q8NEY4 (/IMP)
Transferrin transport GO:0033572
The directed movement of transferrin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
4 Q8NEY4 (/TAS) Q8NEY4 (/TAS) Q8NEY4 (/TAS) Q8NEY4 (/TAS)
Ion transmembrane transport GO:0034220
A process in which an ion is transported across a membrane.
4 Q8NEY4 (/TAS) Q8NEY4 (/TAS) Q8NEY4 (/TAS) Q8NEY4 (/TAS)
Phagosome acidification GO:0090383
Any process that reduces the pH of the phagosome, measured by the concentration of the hydrogen ion.
4 Q8NEY4 (/TAS) Q8NEY4 (/TAS) Q8NEY4 (/TAS) Q8NEY4 (/TAS)
Positive regulation of Wnt signaling pathway GO:0030177
Any process that activates or increases the frequency, rate or extent of Wnt signal transduction.
1 Q99L60 (/ISO)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Lysosomal membrane GO:0005765
The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.
4 Q8NEY4 (/HDA) Q8NEY4 (/HDA) Q8NEY4 (/HDA) Q8NEY4 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
4 Q8NEY4 (/TAS) Q8NEY4 (/TAS) Q8NEY4 (/TAS) Q8NEY4 (/TAS)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
4 Q8NEY4 (/HDA) Q8NEY4 (/HDA) Q8NEY4 (/HDA) Q8NEY4 (/HDA)
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