The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
subunit c (vma5p) of the yeast v-atpase, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: V-type proton ATPase subunit C

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
10 P31412 (/IPI) P31412 (/IPI) P31412 (/IPI) P31412 (/IPI) P31412 (/IPI) P31412 (/IPI) P31412 (/IPI) P31412 (/IPI) P31412 (/IPI) P31412 (/IPI)
Proton-transporting ATPase activity, rotational mechanism GO:0046961
Enables the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out), by a rotational mechanism.
10 P31412 (/TAS) P31412 (/TAS) P31412 (/TAS) P31412 (/TAS) P31412 (/TAS) P31412 (/TAS) P31412 (/TAS) P31412 (/TAS) P31412 (/TAS) P31412 (/TAS)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Vacuolar acidification GO:0007035
Any process that reduces the pH of the vacuole, measured by the concentration of the hydrogen ion.
10 P31412 (/TAS) P31412 (/TAS) P31412 (/TAS) P31412 (/TAS) P31412 (/TAS) P31412 (/TAS) P31412 (/TAS) P31412 (/TAS) P31412 (/TAS) P31412 (/TAS)
Vacuolar acidification GO:0007035
Any process that reduces the pH of the vacuole, measured by the concentration of the hydrogen ion.
1 Q9HDW6 (/ISO)
Proton transmembrane transport GO:1902600
The directed movement of a proton across a membrane.
1 Q9HDW6 (/IC)

There are 9 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Vacuolar proton-transporting V-type ATPase, V1 domain GO:0000221
The V1 domain of a proton-transporting V-type ATPase found in the vacuolar membrane.
10 P31412 (/TAS) P31412 (/TAS) P31412 (/TAS) P31412 (/TAS) P31412 (/TAS) P31412 (/TAS) P31412 (/TAS) P31412 (/TAS) P31412 (/TAS) P31412 (/TAS)
Fungal-type vacuole membrane GO:0000329
The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae.
10 P31412 (/HDA) P31412 (/HDA) P31412 (/HDA) P31412 (/HDA) P31412 (/HDA) P31412 (/HDA) P31412 (/HDA) P31412 (/HDA) P31412 (/HDA) P31412 (/HDA)
Fungal-type vacuole membrane GO:0000329
The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae.
10 P31412 (/TAS) P31412 (/TAS) P31412 (/TAS) P31412 (/TAS) P31412 (/TAS) P31412 (/TAS) P31412 (/TAS) P31412 (/TAS) P31412 (/TAS) P31412 (/TAS)
Vacuolar proton-transporting V-type ATPase, V1 domain GO:0000221
The V1 domain of a proton-transporting V-type ATPase found in the vacuolar membrane.
1 Q9HDW6 (/ISO)
Lysosome GO:0005764
A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
1 P54648 (/IDA)
Early endosome GO:0005769
A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways.
1 P54648 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q9HDW6 (/HDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q5A2U9 (/IDA)
Contractile vacuolar membrane GO:0031164
The lipid bilayer surrounding the contractile vacuole.
1 P54648 (/TAS)
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