View in Gene3D

CATH Superfamily 1.20.1440.90

Phosphoenolpyruvate/pyruvate domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Phosphoenolpyruvate/pyruvate domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 6: Phosphoenolpyruvate carboxylase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Phosphoenolpyruvate carboxylase. [EC: 4.1.1.31]
Phosphate + oxaloacetate = H(2)O + phosphoenolpyruvate + HCO(3)(-).
  • This enzyme replenishes oxaloacetate in the tricarboxylic acid cycle when operating in the reverse direction.
  • The reaction proceeds in two steps: formation of carboxyphosphate and the enolate form of pyruvate, followed by carboxylation of the enolate and release of phosphate.
 4 D6ETJ5 D6ETJ5 Q9RNU9 Q9RNU9