The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
NCX, central ion-binding region
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
696 - - 66.4
2
526 - - 76.0
3
505 - - 72.4
4
441 - - 83.8
5
329 - - 76.1
6
252 - - 68.5
7
228 - - 92.7
8
227 - - 80.9
9
195 - - 97.0
10
164
3D
5hyaA02 - 88.2
11
131 - - 85.0
12
129 - - 82.2
13
117 - - 76.2
14
107 - - 96.0
15
106 - - 81.8
16
68 - - 77.4
17
53 - - 64.3
18
45 - - 76.1
19
38 - - 86.7
20
36 - - 72.2
21
35 - - 81.5
22
34 - - 61.8
23
34 - - 65.2
24
32 - - 78.6
25
28 - - 67.3
26
27 - - 73.8
27
24 - - 81.9
28
23 - - 77.9
29
19 - - 51.2
30
15 - - 53.3
31
14 - - 72.5
32
CaCA
12 - - 10.0
33
11 - - 12.0
35
10 - - 2.5
34
10 - - 2.7
36
9 - - 79.1
37
9 - - 48.8
39
8 - - 68.0
38
8 - - 34.0
40
8 - - 70.2
42
6 - - 13.6
41
6 - - 46.5
43
5 - - 2.0
46
5 - - 6.4
44
5 - - 18.8
45
5 - - 19.6
51
4 - - 34.2
48
4 - - 11.1
49
Ca
2+ +
4 - - 5.2
50
4 - - 8.2
47
4 - - 79.4
53
3 - - 0.0
55
3 - - 5.5
52
3 - - 76.8
56
3 - - 8.3
54
3 - - 0.0
71
2 - - 0.0
58
2 - - 34.0
61
2 - - 0.0
57
2 - - 29.7
74
2 - - 0.0
68
2 - - 27.2
66
2 - - 33.3
59
Ca
2+ +
2 - - 42.8
62
2 - - 10.7
64
2 - - 0.0
60
2 - - 0.0
69
2 - - 12.2
72
2 - - 8.0
73
2 - - 0.0
67
2 - - 33.1
65
CaCA
2 - - 7.8
63
2 - - 0.0
70
2 - - 43.8
75
2 - - 0.0
101
1 - - 0.0
76
1 - - 0.0
96
1 - - 0.0
98
1 - - 0.0
107
1 - - 0.0
87
1 - - 0.0
78
1 - - 0.0
110
1 - - 0.0
112
1 - - 0.0
108
1 - - 0.0
85
1 - - 0.0
102
1 - - 0.0
89
1 - - 0.0
91
1 - - 0.0
80
Ca
2+ +
1 - - 0.0
92
1 - - 0.0
105
1 - - 0.0
111
1 - - 0.0
84
1 - - 0.0
77
Ca
2+ +
1 - - 0.0
100
1 - - 0.0
94
1 - - 0.0
109
1 - - 0.0
82
1 - - 0.0
79
1 - - 0.0
99
1 - - 0.0
90
1 - - 0.0
93
1 - - 0.0
104
1 - - 0.0
103
1 - - 0.0
97
1 - - 0.0
83
1 - - 0.0
95
1 - - 0.0
106
1 - - 0.0
81
1 - - 0.0
86
1 - - 0.0
88
1 - - 0.0
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