The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Poly(ADP-ribose) polymerase, regulatory domain
".
FunFam 31: Poly [ADP-ribose] polymerase 1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 1 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein ADP-ribosylase activity GO:1990404
The transfer, from NAD, of ADP-ribose to a protein amino acid residue.
|
1 | Q08824 (/ISS) |
There are 8 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein ADP-ribosylation GO:0006471
The transfer, from NAD, of ADP-ribose to protein amino acids.
|
1 | Q08824 (/ISS) |
|
Peptidyl-serine ADP-ribosylation GO:0018312
The transfer, from NAD, of ADP-ribose to peptidyl-serine to form peptidyl-O-(ADP-ribosyl)-L-serine.
|
1 | Q08824 (/ISS) |
|
Peptidyl-glutamic acid poly-ADP-ribosylation GO:0018424
This modification produces peptidyl-glutamic acid poly-ADP-ribose found in a number of nuclear proteins under certain conditions including the repair of single strand DNA breaks. The activated form of the generating enzyme poly(ADP-ribose) polymerase is itself modified in this way.
|
1 | Q08824 (/ISS) |
|
DNA ADP-ribosylation GO:0030592
The covalent attachment of an ADP-ribosyl group to a residue in double-stranded DNA.
|
1 | Q08824 (/ISS) |
|
Protein poly-ADP-ribosylation GO:0070212
The transfer of multiple ADP-ribose residues from NAD to a protein amino acid, forming a poly(ADP-ribose) chain.
|
1 | Q08824 (/ISS) |
|
Protein auto-ADP-ribosylation GO:0070213
The ADP-ribosylation by a protein of one or more of its own amino acid residues, or residues on an identical protein.
|
1 | Q08824 (/ISS) |
|
Positive regulation of double-strand break repair via homologous recombination GO:1905168
Any process that activates or increases the frequency, rate or extent of double-strand break repair via homologous recombination.
|
1 | Q08824 (/ISS) |
|
ATP generation from poly-ADP-D-ribose GO:1990966
The process of generating ATP in the nucleus from poly-ADP-D-ribose. Nuclear ATP generation is required for extensive chromatin remodeling events that are energy-consuming.
|
1 | Q08824 (/ISS) |
There are 0 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
