The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 5: Pkp1p

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
[Pyruvate dehydrogenase (acetyl-transferring)] kinase. [EC: 2.7.11.2]
ATP + [pyruvate dehydrogenase (acetyl-transferring)] = ADP + [pyruvate dehydrogenase (acetyl-transferring)] phosphate.
  • Has no activating compound but is specific for its substrate.
  • A mitochondrial enzyme associated with the pyruvate dehydrogenase complex in mammals.
  • Phosphorylation inactivates EC 1.2.4.1.
  • Formerly EC 2.7.1.99.
9 G2WGA4 G2WGA4 G2WGA4 N1P1M9 N1P1M9 N1P1M9 P40530 P40530 P40530
CATH-Gene3D is a Global Biodata Core Resource Learn more...