The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Calcium release-activated calcium channel protein Orai
".
FunFam 2: Uncharacterized protein, isoform B
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | Q9U6B8 (/IPI) Q9U6B8 (/IPI) |
|
Store-operated calcium channel activity GO:0015279
A ligand-gated ion channel activity which transports calcium in response to emptying of intracellular calcium stores.
|
2 | Q9U6B8 (/IDA) Q9U6B8 (/IDA) |
|
Store-operated calcium channel activity GO:0015279
A ligand-gated ion channel activity which transports calcium in response to emptying of intracellular calcium stores.
|
2 | Q9U6B8 (/IMP) Q9U6B8 (/IMP) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
2 | Q9U6B8 (/IPI) Q9U6B8 (/IPI) |
There are 4 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Store-operated calcium entry GO:0002115
A calcium ion entry mechanism in the plasma membrane activated by the depletion of calcium ion from the internal calcium ion store in the endoplasmic reticulum.
|
2 | Q9U6B8 (/IMP) Q9U6B8 (/IMP) |
|
Nervous system development GO:0007399
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
|
2 | Q9U6B8 (/IMP) Q9U6B8 (/IMP) |
|
Positive regulation of calcium ion transport GO:0051928
Any process that activates or increases the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
2 | Q9U6B8 (/IMP) Q9U6B8 (/IMP) |
|
Positive regulation of calcineurin-NFAT signaling cascade GO:0070886
Any process that activates or increases the frequency, rate or extent of signaling via the calcineurin-NFAT signaling cascade.
|
2 | Q9U6B8 (/IMP) Q9U6B8 (/IMP) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | Q9U6B8 (/TAS) Q9U6B8 (/TAS) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | Q9U6B8 (/NAS) Q9U6B8 (/NAS) |