The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Hemocyanin, N-terminal domain
".
FunFam 1: Phenoloxidase 2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 8 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Monophenol monooxygenase activity GO:0004503
Catalysis of the reaction: L-tyrosine + L-DOPA + O2 = L-DOPA + DOPAquinone + H2O.
|
5 | O44249 (/TAS) Q25519 (/TAS) Q25519 (/TAS) Q27451 (/TAS) Q27452 (/TAS) |
|
L-DOPA monooxygenase activity GO:0036263
Catalysis of the reaction: L-DOPA + O2 = ? + H2O. This reaction catalyzes the oxygenation of the dopamine precursor L-DOPA, to the corresponding o-quinone.
|
4 | Q7K2W6 (/IDA) Q9V521 (/IDA) Q9W1V6 (/IDA) Q9W1V6 (/IDA) |
|
Dopamine monooxygenase activity GO:0036264
Catalysis of the reaction: dopamine + O2 = ? + H2O. This reaction catalyzes the oxygenation of dopamine to the corresponding o-quinone.
|
4 | Q7K2W6 (/IDA) Q9V521 (/IDA) Q9W1V6 (/IDA) Q9W1V6 (/IDA) |
|
Copper ion binding GO:0005507
Interacting selectively and non-covalently with copper (Cu) ions.
|
3 | O44249 (/ISS) Q25519 (/ISS) Q25519 (/ISS) |
|
Chloride ion binding GO:0031404
Interacting selectively and non-covalently with chloride ions (Cl-).
|
3 | O44249 (/ISS) Q25519 (/ISS) Q25519 (/ISS) |
|
Catechol oxidase activity GO:0004097
Catalysis of the reaction: 2 catechol + O2 = 2 1,2-benzoquinone + 2 H2O.
|
1 | Q7K2W6 (/IDA) |
|
Monophenol monooxygenase activity GO:0004503
Catalysis of the reaction: L-tyrosine + L-DOPA + O2 = L-DOPA + DOPAquinone + H2O.
|
1 | Q7K2W6 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q27598 (/IPI) |
There are 17 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Melanin biosynthetic process from tyrosine GO:0006583
The chemical reactions and pathways resulting in the formation of melanin from other compounds, including tyrosine.
|
5 | O44249 (/TAS) Q25519 (/TAS) Q25519 (/TAS) Q27451 (/TAS) Q27452 (/TAS) |
|
Defense response GO:0006952
Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
|
4 | Q25519 (/TAS) Q25519 (/TAS) Q27451 (/TAS) Q27452 (/TAS) |
|
Dopamine metabolic process GO:0042417
The chemical reactions and pathways involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
|
4 | Q7K2W6 (/IC) Q9V521 (/IC) Q9W1V6 (/IC) Q9W1V6 (/IC) |
|
Melanotic encapsulation of foreign target GO:0035011
Formation of a multilayered, melanized sheath of cells around a foreign invader.
|
3 | Q9V521 (/IGI) Q9W1V6 (/IGI) Q9W1V6 (/IGI) |
|
Melanization defense response GO:0035006
The blackening of the wounded area of the cuticle or the surface of invading pathogens, parasites or parasitoids, resulting from a proteolytic cascade leading to the de novo synthesis and deposition of melanin.
|
2 | Q7K2W6 (/IGI) Q9V521 (/IGI) |
|
Melanization defense response GO:0035006
The blackening of the wounded area of the cuticle or the surface of invading pathogens, parasites or parasitoids, resulting from a proteolytic cascade leading to the de novo synthesis and deposition of melanin.
|
2 | Q7K2W6 (/IMP) Q9V521 (/IMP) |
|
Positive regulation of melanization defense response GO:0035008
Any process that increases the rate or extent of the melanization defense response during injury or invasion.
|
2 | Q25519 (/NAS) Q25519 (/NAS) |
|
Defense response to Gram-positive bacterium GO:0050830
Reactions triggered in response to the presence of a Gram-positive bacterium that act to protect the cell or organism.
|
2 | Q7K2W6 (/IGI) Q9V521 (/IGI) |
|
Defense response to fungus GO:0050832
Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.
|
2 | Q7K2W6 (/IGI) Q9V521 (/IGI) |
|
Defense response to fungus GO:0050832
Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.
|
2 | Q7K2W6 (/IMP) Q9V521 (/IMP) |
|
Defense response GO:0006952
Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
|
1 | O44249 (/NAS) |
|
Response to wounding GO:0009611
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
|
1 | Q7K2W6 (/IMP) |
|
Positive regulation of melanization defense response GO:0035008
Any process that increases the rate or extent of the melanization defense response during injury or invasion.
|
1 | O44249 (/IDA) |
|
Scab formation GO:0035314
Formation of hardened covering (a scab) at a wound site. The scab has multiple functions including limiting blood loss, providing structural stability to the wound and guarding against infection.
|
1 | Q7K2W6 (/IMP) |
|
Wound healing GO:0042060
The series of events that restore integrity to a damaged tissue, following an injury.
|
1 | Q7K2W6 (/IMP) |
|
Hemolymph coagulation GO:0042381
Any process in which factors in the hemolymph (the invertebrate equivalent of vertebrate blood and lymph) precipitate into insoluble clots in order to prevent loss of body fluid, and at the same time prevent the movement of microbes. Hemolymph coagulation is also part of the invertebrate humoral immune response.
|
1 | Q7K2W6 (/IMP) |
|
Defense response to Gram-positive bacterium GO:0050830
Reactions triggered in response to the presence of a Gram-positive bacterium that act to protect the cell or organism.
|
1 | Q7K2W6 (/IMP) |
There are 5 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
6 | O44249 (/IDA) Q25519 (/IDA) Q25519 (/IDA) Q9V521 (/IDA) Q9W1V6 (/IDA) Q9W1V6 (/IDA) |
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
2 | Q7K2W6 (/HDA) Q9V521 (/HDA) |
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
2 | Q27451 (/TAS) Q27452 (/TAS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | Q9W1V6 (/HDA) Q9W1V6 (/HDA) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
1 | Q9V521 (/IDA) |
