CATH Superfamily 1.20.1300.10
Fumarate reductase/succinate dehydrogenase, transmembrane subunit
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Fumarate reductase/succinate dehydrogenase, transmembrane subunit
".
FunFam 11: Succinate dehydrogenase cytochrome b560 subunit
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Succinate dehydrogenase (ubiquinone) activity GO:0008177
Catalysis of the reaction: succinate + ubiquinone = fumarate + ubiquinol.
|
3 | Q8MYW1 (/ISS) Q9VGS3 (/ISS) Q9VGS3 (/ISS) |
Heme binding GO:0020037
Interacting selectively and non-covalently with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.
|
2 | P41955 (/ISS) P41956 (/ISS) |
There are 9 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Mitochondrial electron transport, succinate to ubiquinone GO:0006121
The transfer of electrons from succinate to ubiquinone that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex II.
|
4 | P41956 (/IMP) Q8MYW1 (/IMP) Q9VGS3 (/IMP) Q9VGS3 (/IMP) |
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
|
4 | P41956 (/IMP) Q8MYW1 (/IMP) Q9VGS3 (/IMP) Q9VGS3 (/IMP) |
Determination of adult lifespan GO:0008340
The control of viability and duration in the adult phase of the life-cycle.
|
4 | P41956 (/IMP) Q8MYW1 (/IMP) Q9VGS3 (/IMP) Q9VGS3 (/IMP) |
Tricarboxylic acid cycle GO:0006099
A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.
|
3 | Q8MYW1 (/ISS) Q9VGS3 (/ISS) Q9VGS3 (/ISS) |
Determination of adult lifespan GO:0008340
The control of viability and duration in the adult phase of the life-cycle.
|
1 | P41956 (/IGI) |
Innate immune response GO:0045087
Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.
|
1 | P41956 (/IMP) |
Defense response to Gram-negative bacterium GO:0050829
Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.
|
1 | P41956 (/IMP) |
Negative regulation of response to oxidative stress GO:1902883
Any process that stops, prevents or reduces the frequency, rate or extent of response to oxidative stress.
|
1 | P41956 (/IGI) |
Positive regulation of response to oxidative stress GO:1902884
Any process that activates or increases the frequency, rate or extent of response to oxidative stress.
|
1 | P41956 (/IMP) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) GO:0005749
A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains the four polypeptide subunits of succinate dehydrogenase, flavin-adenine dinucleotide and iron-sulfur. Catalyzes the oxidation of succinate by ubiquinone. Connects the TCA cycle with the respiratory chain.
|
5 | P41955 (/ISS) P41956 (/ISS) Q8MYW1 (/ISS) Q9VGS3 (/ISS) Q9VGS3 (/ISS) |
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
|
2 | P41955 (/ISS) P41956 (/ISS) |
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | P41956 (/HDA) |