The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 55: F-box/SPRY domain-containing protein 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protease binding GO:0002020
Interacting selectively and non-covalently with any protease or peptidase.
1 Q18223 (/IPI)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q18223 (/IPI)

There are 19 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Neuromuscular synaptic transmission GO:0007274
The process of synaptic transmission from a neuron to a muscle, across a synapse.
5 B0X9V1 (/ISS) B0X9V1 (/ISS) Q16XV7 (/ISS) Q16XV7 (/ISS) Q7QGL9 (/ISS)
Negative regulation of synaptic growth at neuromuscular junction GO:0045886
Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic growth at neuromuscular junction.
5 B0X9V1 (/ISS) B0X9V1 (/ISS) Q16XV7 (/ISS) Q16XV7 (/ISS) Q7QGL9 (/ISS)
Ubiquitin-dependent protein catabolic process GO:0006511
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.
1 Q18223 (/IDA)
Determination of adult lifespan GO:0008340
The control of viability and duration in the adult phase of the life-cycle.
1 Q18223 (/IMP)
Regulation of synaptic growth at neuromuscular junction GO:0008582
Any process that modulates the frequency, rate or extent of synaptic growth at neuromuscular junctions.
1 Q18223 (/IGI)
Response to ionizing radiation GO:0010212
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays.
1 Q18223 (/IMP)
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 Q18223 (/IMP)
Negative regulation of axon extension GO:0030517
Any process that stops, prevents, or reduces the frequency, rate or extent of axon outgrowth.
1 Q18223 (/IGI)
Dauer larval development GO:0040024
The process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.
1 Q18223 (/IGI)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
1 Q18223 (/IMP)
Negative regulation of DNA damage response, signal transduction by p53 class mediator GO:0043518
Any process that stops, prevents, or reduces the frequency, rate or extent of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.
1 Q18223 (/IMP)
Positive regulation of synaptic growth at neuromuscular junction GO:0045887
Any process that activates or increases the frequency, rate or extent of synaptic growth at neuromuscular junction.
1 Q18223 (/IGI)
Positive regulation of synaptic growth at neuromuscular junction GO:0045887
Any process that activates or increases the frequency, rate or extent of synaptic growth at neuromuscular junction.
1 Q18223 (/IMP)
Negative regulation of axon regeneration GO:0048681
Any process that stops, prevents, or reduces the frequency, rate or extent of axon regeneration.
1 Q18223 (/IMP)
Positive regulation of synapse assembly GO:0051965
Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.
1 Q18223 (/IMP)
Regulation of neuromuscular synaptic transmission GO:1900073
Any process that modulates the frequency, rate or extent of neuromuscular synaptic transmission.
1 Q18223 (/IGI)
Positive regulation of neuromuscular synaptic transmission GO:1900075
Any process that activates or increases the frequency, rate or extent of neuromuscular synaptic transmission.
1 Q18223 (/IGI)
Positive regulation of neuromuscular synaptic transmission GO:1900075
Any process that activates or increases the frequency, rate or extent of neuromuscular synaptic transmission.
1 Q18223 (/IMP)
Positive regulation of protein localization to nucleus GO:1900182
Any process that activates or increases the frequency, rate or extent of protein localization to nucleus.
1 Q18223 (/IMP)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Neuromuscular junction GO:0031594
The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential.
5 B0X9V1 (/ISS) B0X9V1 (/ISS) Q16XV7 (/ISS) Q16XV7 (/ISS) Q7QGL9 (/ISS)
Neuromuscular junction GO:0031594
The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential.
1 Q18223 (/IDA)
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
1 Q18223 (/IDA)
Presynapse GO:0098793
The part of a synapse that is part of the presynaptic cell.
1 Q18223 (/IDA)
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