CATH Superfamily 1.20.1280.50
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 107: JmjC domain-containing histone demethylation prote...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Histone demethylase activity (H3-trimethyl-K4 specific) GO:0034647
Catalysis of the removal of a methyl group from trimethylated lysine at position 4 of the histone H3 protein.
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2 | Q9VHH9 (/IMP) Q9VHH9 (/IMP) |
|
Histone demethylase activity (H3-K36 specific) GO:0051864
Catalysis of the reaction: histone H3 N6-methyl-L-lysine (position 36) + alpha-ketoglutarate + O2 = succinate + CO2 + formaldehyde + lysine. This reaction is the removal of a methyl group from lysine at position 36 of the histone H3 protein.
|
2 | Q9VHH9 (/ISS) Q9VHH9 (/ISS) |
There are 11 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Segment specification GO:0007379
The process in which segments assume individual identities; exemplified in insects by the actions of the products of the homeotic genes.
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2 | Q9VHH9 (/IGI) Q9VHH9 (/IGI) |
|
Larval somatic muscle development GO:0007526
The process whose specific outcome is the progression of the larval somatic muscle over time, from its formation to the mature structure.
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2 | Q9VHH9 (/IEP) Q9VHH9 (/IEP) |
|
Larval somatic muscle development GO:0007526
The process whose specific outcome is the progression of the larval somatic muscle over time, from its formation to the mature structure.
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2 | Q9VHH9 (/IMP) Q9VHH9 (/IMP) |
|
Negative regulation of histone methylation GO:0031061
Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of methyl groups to histones.
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2 | Q9VHH9 (/IMP) Q9VHH9 (/IMP) |
|
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031146
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome.
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2 | Q9VHH9 (/ISM) Q9VHH9 (/ISM) |
|
Negative regulation of histone ubiquitination GO:0033183
Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of a ubiquitin group to a histone protein.
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2 | Q9VHH9 (/IMP) Q9VHH9 (/IMP) |
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Histone H2A ubiquitination GO:0033522
The modification of histone H2A by addition of one or more ubiquitin groups.
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2 | Q9VHH9 (/IDA) Q9VHH9 (/IDA) |
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Histone H2A ubiquitination GO:0033522
The modification of histone H2A by addition of one or more ubiquitin groups.
|
2 | Q9VHH9 (/IMP) Q9VHH9 (/IMP) |
|
Histone H3-K4 demethylation, trimethyl-H3-K4-specific GO:0034721
The modification of histone H3 by the removal of a methyl group from a trimetylated lysine at position 4 of the histone.
|
2 | Q9VHH9 (/IMP) Q9VHH9 (/IMP) |
|
Histone H3-K36 demethylation GO:0070544
The modification of histone H3 by the removal of a methyl group from lysine at position 36 of the histone.
|
2 | Q9VHH9 (/IDA) Q9VHH9 (/IDA) |
|
Histone H3-K36 demethylation GO:0070544
The modification of histone H3 by the removal of a methyl group from lysine at position 36 of the histone.
|
2 | Q9VHH9 (/IMP) Q9VHH9 (/IMP) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
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2 | Q9VHH9 (/IDA) Q9VHH9 (/IDA) |
|
SCF ubiquitin ligase complex GO:0019005
A ubiquitin ligase complex in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1).
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2 | Q9VHH9 (/ISM) Q9VHH9 (/ISM) |
|
PcG protein complex GO:0031519
A chromatin-associated multiprotein complex containing Polycomb Group proteins. In Drosophila, Polycomb group proteins are involved in the long-term maintenance of gene repression, and PcG protein complexes associate with Polycomb group response elements (PREs) in target genes to regulate higher-order chromatin structure.
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2 | Q9VHH9 (/IPI) Q9VHH9 (/IPI) |
