View in Gene3D

CATH Superfamily 1.20.1260.30

N6 adenine-specific DNA methyltransferase, N-terminal domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: N6 adenine-specific DNA methyltransferase, N-terminal domain

This domain is found at the N terminus of the methylase subunit of Type I DNA methyltransferases. It is found in association with PFAM:PF02384. Mutations in this region of EcoKI methyltransferase abolish the normally strong preference of this system for methylating hemimethylated substrate PMID:1833555. The structure of this domain has been shown to be all alpha-helical. PMID:1833555 (INTERPRO:IPR022749)

GO Diversity

Unique GO annotations
8 Unique GO terms

EC Diversity

Unique EC annotations
1 Unique EC terms

Species Diversity

Unique species annotations
7792 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 9
Domain clusters (>95% seq id): 5
Domain clusters (>35% seq id): 5
Unique PDBs: 5
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 3
Function
Unique EC: 1
Unique GO: 8
Taxonomy
Unique Species: 7792