The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
MFS general substrate transporter like domains
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 85: MFS peptide transporter Ptr2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Dipeptide transmembrane transporter activity GO:0071916
Enables the transfer of a dipeptide from one side of a membrane to the other. A dipeptide is a combination of two amino acids linked together by a peptide (-CO-NH-) bond.
4 A0A1D8PS27 (/IMP) Q59ST2 (/IMP) Q59ST2 (/IMP) Q9P380 (/IMP)
Tripeptide transmembrane transporter activity GO:0042937
Enables the transfer of a tripeptide, a compound containing three amino acids linked together by peptide bonds, from one side of a membrane to the other.
3 A0A1D8PS27 (/IMP) Q59ST2 (/IMP) Q59ST2 (/IMP)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 P32901 (/IPI)
Tripeptide transmembrane transporter activity GO:0042937
Enables the transfer of a tripeptide, a compound containing three amino acids linked together by peptide bonds, from one side of a membrane to the other.
1 P32901 (/IDA)
Tripeptide transmembrane transporter activity GO:0042937
Enables the transfer of a tripeptide, a compound containing three amino acids linked together by peptide bonds, from one side of a membrane to the other.
1 Q9P380 (/ISO)
Dipeptide transmembrane transporter activity GO:0071916
Enables the transfer of a dipeptide from one side of a membrane to the other. A dipeptide is a combination of two amino acids linked together by a peptide (-CO-NH-) bond.
1 P32901 (/IDA)
Peptide transmembrane transporter activity GO:1904680
Enables the transfer of a peptide from one side of a membrane to the other.
1 P32901 (/IMP)

There are 8 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Dipeptide transport GO:0042938
The directed movement of a dipeptide, a combination of two amino acids by means of a peptide (-CO-NH-) link, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
3 A0A1D8PS27 (/IMP) Q59ST2 (/IMP) Q59ST2 (/IMP)
Tripeptide transport GO:0042939
The directed movement of a tripeptide, a compound containing three amino acids linked together by peptide bonds, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
3 A0A1D8PS27 (/IMP) Q59ST2 (/IMP) Q59ST2 (/IMP)
Peptide transport GO:0015833
The directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 P32901 (/IMP)
Dipeptide transmembrane transport GO:0035442
The directed movement of a dipeptide across a membrane by means of some agent such as a transporter or pore. A dipeptide is a combination of two amino acids linked together by a peptide (-CO-NH-) bond.
1 Q9P380 (/IMP)
Dipeptide transport GO:0042938
The directed movement of a dipeptide, a combination of two amino acids by means of a peptide (-CO-NH-) link, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 P32901 (/IDA)
Tripeptide transport GO:0042939
The directed movement of a tripeptide, a compound containing three amino acids linked together by peptide bonds, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 P32901 (/IDA)
Dipeptide import across plasma membrane GO:0140206
The directed movement of a dipeptide from outside of a cell, across the plasma membrane and into the cytosol.
1 Q9P380 (/ISO)
Tripeptide import across plasma membrane GO:0140207
The directed movement of a tripeptide from outside of a cell, across the plasma membrane and into the cytosol.
1 Q9P380 (/ISO)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Fungal-type vacuole GO:0000324
A vacuole that has both lytic and storage functions. The fungal vacuole is a large, membrane-bounded organelle that functions as a reservoir for the storage of small molecules (including polyphosphate, amino acids, several divalent cations (e.g. calcium), other ions, and other small molecules) as well as being the primary compartment for degradation. It is an acidic compartment, containing an ensemble of acid hydrolases. At least in S. cerevisiae, there are indications that the morphology of the vacuole is variable and correlated with the cell cycle, with logarithmically growing cells having a multilobed, reticulated vacuole, while stationary phase cells contain a single large structure.
2 P32901 (/HDA) Q9P380 (/HDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 P32901 (/IDA)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q9P380 (/ISO)
Plasma membrane of cell tip GO:0031520
The portion of the plasma membrane surrounding the cell tip.
1 Q9P380 (/IDA)
Cell division site GO:0032153
The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.
1 Q9P380 (/IDA)
Cell periphery GO:0071944
The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures.
1 P32901 (/HDA)
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