The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"MFS general substrate transporter like domains
".
FunFam 67: sialin isoform X2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Sialic acid transmembrane transporter activity GO:0015136
Enables the transfer of sialic acid from one side of a membrane to the other.
|
2 | Q5Q0U0 (/IDA) Q9NRA2 (/IDA) |
|
Carbohydrate:proton symporter activity GO:0005351
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sugar(out) + H+(out) = sugar(in) + H+(in).
|
1 | Q9NRA2 (/TAS) |
|
Sialic acid transmembrane transporter activity GO:0015136
Enables the transfer of sialic acid from one side of a membrane to the other.
|
1 | Q8BN82 (/ISO) |
|
Sialic acid:proton symporter activity GO:0015538
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sialate(out) + H+(out) = sialate(in) + H+(in).
|
1 | Q9NRA2 (/TAS) |
There are 5 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Sialic acid transport GO:0015739
The directed movement of sialic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
2 | Q5Q0U0 (/IDA) Q9NRA2 (/IDA) |
|
Ion transport GO:0006811
The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | Q9NRA2 (/TAS) |
|
Anion transport GO:0006820
The directed movement of anions, atoms or small molecules with a net negative charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | Q9NRA2 (/TAS) |
|
Response to bacterium GO:0009617
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.
|
1 | Q8BN82 (/IEP) |
|
Sialic acid transport GO:0015739
The directed movement of sialic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | Q8BN82 (/ISO) |
There are 14 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Lysosomal membrane GO:0005765
The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.
|
2 | B2RE38 (/HDA) Q9NRA2 (/HDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | Q8BN82 (/IDA) Q9NRA2 (/IDA) |
|
Sarcoplasmic reticulum GO:0016529
A fine reticular network of membrane-limited elements that pervades the sarcoplasm of a muscle cell; continuous over large portions of the cell and with the nuclear envelope; that part of the endoplasmic reticulum specialized for calcium release, uptake and storage.
|
2 | Q23514 (/HDA) Q2PJ91 (/HDA) |
|
Lysosome GO:0005764
A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
|
1 | Q5Q0U0 (/IDA) |
|
Lysosome GO:0005764
A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
|
1 | Q8BN82 (/ISO) |
|
Lysosomal membrane GO:0005765
The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.
|
1 | Q9NRA2 (/IDA) |
|
Lysosomal membrane GO:0005765
The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.
|
1 | Q8BN82 (/ISO) |
|
Lysosomal membrane GO:0005765
The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.
|
1 | Q9NRA2 (/TAS) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q9NRA2 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q8BN82 (/ISO) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q8BN82 (/ISO) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q9NRA2 (/TAS) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | Q9NRA2 (/TAS) |
|
Cytoplasmic vesicle GO:0031410
A vesicle found in the cytoplasm of a cell.
|
1 | Q8BN82 (/IDA) |
