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CATH Superfamily 1.20.1250.20

MFS general substrate transporter like domains

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
MFS general substrate transporter like domains
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 51: Proline/glycine betaine transporter

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Glycine betaine:proton symporter activity GO:0015653
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine betaine(out) + H+(out) = glycine betaine(in) + H+(in).
 39 P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA)
(29 more)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Amino acid transport GO:0006865
The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
 39 P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA)
(29 more)
Osmosensory signaling pathway GO:0007231
The series of molecular signals initiated in response to osmotic change.
 39 P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA)
(29 more)
Cellular hyperosmotic salinity response GO:0071475
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
 39 P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA)
(29 more)
Proline import across plasma membrane GO:1905647
The directed movement of proline from outside of a cell into the cytoplasmic compartment.
 39 P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA)
(29 more)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
 39 P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA)
(29 more)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
 39 P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA)
(29 more)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
 39 P0C0L7 (/RCA) P0C0L7 (/RCA) P0C0L7 (/RCA) P0C0L7 (/RCA) P0C0L7 (/RCA) P0C0L7 (/RCA) P0C0L7 (/RCA) P0C0L7 (/RCA) P0C0L7 (/RCA) P0C0L7 (/RCA)
(29 more)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
 39 P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA) P0C0L7 (/IDA)
(29 more)
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