The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
MFS general substrate transporter like domains
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 210: Solute carrier organic anion transporter family me...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 11 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Organic anion transmembrane transporter activity GO:0008514
Enables the transfer of organic anions from one side of a membrane to the other. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage.
5 O35913 (/IDA) O88397 (/IDA) Q9EP96 (/IDA) Q9QXZ6 (/IDA) Q9QXZ6 (/IDA)
Organic anion transmembrane transporter activity GO:0008514
Enables the transfer of organic anions from one side of a membrane to the other. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage.
5 O88397 (/TAS) P46720 (/TAS) P46721 (/TAS) P46721 (/TAS) P70502 (/TAS)
Organic anion transmembrane transporter activity GO:0008514
Enables the transfer of organic anions from one side of a membrane to the other. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage.
2 Q91YY5 (/ISO) Q9EP96 (/ISO)
Bile acid transmembrane transporter activity GO:0015125
Enables the transfer of bile acid from one side of a membrane to the other. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.
2 O35913 (/IDA) O88397 (/IDA)
Bile acid transmembrane transporter activity GO:0015125
Enables the transfer of bile acid from one side of a membrane to the other. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.
2 Q91YY5 (/ISO) Q9EP96 (/ISO)
Bile acid transmembrane transporter activity GO:0015125
Enables the transfer of bile acid from one side of a membrane to the other. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.
2 P46721 (/TAS) P46721 (/TAS)
Monocarboxylic acid transmembrane transporter activity GO:0008028
Enables the transfer of monocarboxylic acids from one side of a membrane to the other. A monocarboxylic acid is an organic acid with one COOH group.
1 O88397 (/IDA)
Monocarboxylic acid transmembrane transporter activity GO:0008028
Enables the transfer of monocarboxylic acids from one side of a membrane to the other. A monocarboxylic acid is an organic acid with one COOH group.
1 Q91YY5 (/ISO)
Thyroid hormone transmembrane transporter activity GO:0015349
Enables the transfer of thyroid hormones from one side of a membrane to the other. Thyroid hormone are any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine.
1 O88397 (/IDA)
Thyroid hormone transmembrane transporter activity GO:0015349
Enables the transfer of thyroid hormones from one side of a membrane to the other. Thyroid hormone are any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine.
1 Q91YY5 (/ISO)
Methotrexate transmembrane transporter activity GO:0015350
Enables the transfer of methotrexate, 4-amino-10-methylformic acid from one side of a membrane to the other. Methotrexate is a folic acid analogue and a potent competitive inhibitor of dihydrofolate reductase.
1 P70502 (/IDA)

There are 19 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Organic anion transport GO:0015711
The directed movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage.
5 O88397 (/TAS) P46720 (/TAS) P46721 (/TAS) P46721 (/TAS) P70502 (/TAS)
Organic anion transport GO:0015711
The directed movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage.
3 O88397 (/IDA) Q9QXZ6 (/IDA) Q9QXZ6 (/IDA)
Bile acid and bile salt transport GO:0015721
The directed movement of bile acid and bile salts into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 P46721 (/TAS) P46721 (/TAS)
Response to stilbenoid GO:0035634
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of exposure to a stilbenoid. Stilbenoids are secondary products of heartwood formation in trees that can act as phytoalexins. Stilbenoids are hydroxylated derivatives of stilbene. They belong to the family of phenylpropanoids and share most of their biosynthesis pathway with chalcones.
2 Q9QXZ6 (/IEP) Q9QXZ6 (/IEP)
Sodium-independent organic anion transport GO:0043252
The directed, sodium-independent, movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 P46721 (/TAS) P46721 (/TAS)
Anion transport GO:0006820
The directed movement of anions, atoms or small molecules with a net negative charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q9EP96 (/IDA)
Organic anion transport GO:0015711
The directed movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage.
1 P46720 (/IEP)
Organic anion transport GO:0015711
The directed movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage.
1 Q91YY5 (/ISO)
Monocarboxylic acid transport GO:0015718
The directed movement of monocarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 O88397 (/IMP)
Monocarboxylic acid transport GO:0015718
The directed movement of monocarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q91YY5 (/ISO)
Bile acid and bile salt transport GO:0015721
The directed movement of bile acid and bile salts into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 O88397 (/IDA)
Bile acid and bile salt transport GO:0015721
The directed movement of bile acid and bile salts into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q91YY5 (/ISO)
Drug transport GO:0015893
The directed movement of a drug, a substance used in the diagnosis, treatment or prevention of a disease, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 P70502 (/IDA)
Animal organ regeneration GO:0031100
The regrowth of a lost or destroyed animal organ.
1 O88397 (/IEP)
Response to testosterone GO:0033574
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus.
1 P46720 (/IEP)
Sodium-independent organic anion transport GO:0043252
The directed, sodium-independent, movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 O35913 (/IDA)
Sodium-independent organic anion transport GO:0043252
The directed, sodium-independent, movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q9EP96 (/ISO)
Intestinal absorption GO:0050892
Any process in which nutrients are taken up from the contents of the intestine.
1 O88397 (/IMP)
Intestinal absorption GO:0050892
Any process in which nutrients are taken up from the contents of the intestine.
1 Q91YY5 (/ISO)

There are 10 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
4 A0A024RAT5 (/IDA) A0A024RAT5 (/IDA) P46721 (/IDA) P46721 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
3 Q9EP96 (/IDA) Q9QXZ6 (/IDA) Q9QXZ6 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 P46721 (/TAS) P46721 (/TAS)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 Q9QXZ6 (/IDA) Q9QXZ6 (/IDA)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 O88397 (/TAS) P46720 (/TAS)
Basolateral plasma membrane GO:0016323
The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
2 Q9QXZ6 (/IDA) Q9QXZ6 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q91YY5 (/ISO)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q91YY5 (/ISO)
Brush border membrane GO:0031526
The portion of the plasma membrane surrounding the brush border.
1 O88397 (/IDA)
Brush border membrane GO:0031526
The portion of the plasma membrane surrounding the brush border.
1 Q91YY5 (/ISO)
CATH-Gene3D is a Global Biodata Core Resource Learn more...