The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
MFS general substrate transporter like domains
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 180: MFS monosaccharide transporter

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
High-affinity glucose:proton symporter activity GO:0005358
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose + H+ = glucose + H+. This activity is constitutive and therefore always present, regardless of demand. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
5 Q5ASJ3 (/IDA) Q5ASJ3 (/IDA) Q5AYG1 (/IDA) Q5AYG1 (/IDA) Q5AYG1 (/IDA)
High-affinity glucose:proton symporter activity GO:0005358
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose + H+ = glucose + H+. This activity is constitutive and therefore always present, regardless of demand. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
5 Q5ASJ3 (/IMP) Q5ASJ3 (/IMP) Q5AYG1 (/IMP) Q5AYG1 (/IMP) Q5AYG1 (/IMP)
Monosaccharide transmembrane transporter activity GO:0015145
Enables the transfer of a monosaccharide from one side of a membrane to the other.
4 Q8J0V1 (/IDA) Q8J0V1 (/IDA) Q8J0V1 (/IDA) Q8J0V1 (/IDA)
Monosaccharide transmembrane transporter activity GO:0015145
Enables the transfer of a monosaccharide from one side of a membrane to the other.
4 Q8J0V1 (/IMP) Q8J0V1 (/IMP) Q8J0V1 (/IMP) Q8J0V1 (/IMP)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Carbohydrate transmembrane transport GO:0034219
The process in which a carbohydrate is transported across a membrane.
4 Q8J0V1 (/IDA) Q8J0V1 (/IDA) Q8J0V1 (/IDA) Q8J0V1 (/IDA)
Carbohydrate transmembrane transport GO:0034219
The process in which a carbohydrate is transported across a membrane.
4 Q8J0V1 (/IMP) Q8J0V1 (/IMP) Q8J0V1 (/IMP) Q8J0V1 (/IMP)
Glucose transmembrane transport GO:1904659
The process in which glucose is transported across a membrane.
3 Q5AYG1 (/IDA) Q5AYG1 (/IDA) Q5AYG1 (/IDA)
Glucose transmembrane transport GO:1904659
The process in which glucose is transported across a membrane.
3 Q5AYG1 (/IMP) Q5AYG1 (/IMP) Q5AYG1 (/IMP)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
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