The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"MFS general substrate transporter like domains
".
FunFam 179: Solute carrier family 16 member 2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Thyroid hormone transmembrane transporter activity GO:0015349
Enables the transfer of thyroid hormones from one side of a membrane to the other. Thyroid hormone are any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine.
|
3 | O70324 (/ISS) O70324 (/ISS) Q8K1P8 (/ISS) |
Thyroid hormone transmembrane transporter activity GO:0015349
Enables the transfer of thyroid hormones from one side of a membrane to the other. Thyroid hormone are any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine.
|
2 | P36021 (/IMP) Q8K1P8 (/IMP) |
Thyroid hormone transmembrane transporter activity GO:0015349
Enables the transfer of thyroid hormones from one side of a membrane to the other. Thyroid hormone are any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine.
|
2 | O70324 (/ISO) O70324 (/ISO) |
Thyroid hormone binding GO:0070324
Interacting selectively and non-covalently with thyroxine (T4) or triiodothyronine (T3), tyrosine-based hormones produced by the thyroid gland.
|
2 | G8XYX6 (/IDA) L7T0T8 (/IDA) |
Transporter activity GO:0005215
Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells.
|
1 | P36021 (/TAS) |
Monocarboxylic acid transmembrane transporter activity GO:0008028
Enables the transfer of monocarboxylic acids from one side of a membrane to the other. A monocarboxylic acid is an organic acid with one COOH group.
|
1 | P36021 (/TAS) |
There are 17 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Thyroid hormone transport GO:0070327
The directed movement of thyroid hormone into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
3 | O70324 (/ISS) O70324 (/ISS) Q8K1P8 (/ISS) |
Central nervous system development GO:0007417
The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
|
2 | G8XYX6 (/IMP) L7T0T8 (/IMP) |
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
|
2 | G8XYX6 (/IMP) L7T0T8 (/IMP) |
Hormone transport GO:0009914
The directed movement of hormones into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
2 | O70324 (/ISO) O70324 (/ISO) |
Schwann cell differentiation GO:0014037
The process in which a relatively unspecialized cell acquires the specialized features of a Schwann cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function.
|
2 | G8XYX6 (/IMP) L7T0T8 (/IMP) |
Spinal cord development GO:0021510
The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues.
|
2 | G8XYX6 (/IMP) L7T0T8 (/IMP) |
Spinal cord oligodendrocyte cell differentiation GO:0021529
The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of oligodendrocytes. Oligodendrocytes are non-neuronal cells. The primary function of oligodendrocytes is the myelination of nerve axons in the central nervous system. Differentiation includes the processes involved in commitment of a cell to a specific fate.
|
2 | G8XYX6 (/IMP) L7T0T8 (/IMP) |
Neuron differentiation GO:0030182
The process in which a relatively unspecialized cell acquires specialized features of a neuron.
|
2 | G8XYX6 (/IMP) L7T0T8 (/IMP) |
Thyroid gland development GO:0030878
The process whose specific outcome is the progression of the thyroid gland over time, from its formation to the mature structure. The thyroid gland is an endoderm-derived gland that produces thyroid hormone.
|
2 | G8XYX6 (/IMP) L7T0T8 (/IMP) |
Locomotion GO:0040011
Self-propelled movement of a cell or organism from one location to another.
|
2 | G8XYX6 (/IMP) L7T0T8 (/IMP) |
Chordate embryonic development GO:0043009
The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching.
|
2 | G8XYX6 (/IMP) L7T0T8 (/IMP) |
Oligodendrocyte differentiation GO:0048709
The process in which a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system.
|
2 | G8XYX6 (/IMP) L7T0T8 (/IMP) |
Thyroid hormone transport GO:0070327
The directed movement of thyroid hormone into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
2 | O70324 (/ISO) O70324 (/ISO) |
Hormone transport GO:0009914
The directed movement of hormones into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | Q8K1P8 (/IMP) |
Monocarboxylic acid transport GO:0015718
The directed movement of monocarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | P36021 (/TAS) |
Sodium-independent organic anion transport GO:0043252
The directed, sodium-independent, movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | P36021 (/TAS) |
Thyroid hormone transport GO:0070327
The directed movement of thyroid hormone into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | P36021 (/IMP) |
There are 6 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
3 | O70324 (/ISS) O70324 (/ISS) Q8K1P8 (/ISS) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | O70324 (/ISO) O70324 (/ISO) |
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | O70324 (/ISO) O70324 (/ISO) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | P36021 (/IDA) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | P36021 (/TAS) |
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | P36021 (/IDA) |