The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"MFS general substrate transporter like domains
".
FunFam 165: Solute carrier family 22 member 3
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 12 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Organic cation transmembrane transporter activity GO:0015101
Enables the transfer of organic cations from one side of a membrane to the other. Organic cations are atoms or small molecules with a positive charge that contain carbon in covalent linkage.
|
4 | O75751 (/IDA) O88446 (/IDA) Q9WTW5 (/IDA) Q9WTW5 (/IDA) |
|
Quaternary ammonium group transmembrane transporter activity GO:0015651
Enables the transfer of quaternary ammonium groups from one side of a membrane to the other. Quaternary ammonium groups are any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups.
|
3 | O75751 (/IDA) Q9WTW5 (/IDA) Q9WTW5 (/IDA) |
|
Dopamine:sodium symporter activity GO:0005330
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dopamine(out) + Na+(out) + Cl-(out)= dopamine(in) + Na+(in) + Cl-(in).
|
2 | Q9WTW5 (/ISO) Q9WTW5 (/ISO) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | O75751 (/IPI) O88446 (/IPI) |
|
Organic cation transmembrane transporter activity GO:0015101
Enables the transfer of organic cations from one side of a membrane to the other. Organic cations are atoms or small molecules with a positive charge that contain carbon in covalent linkage.
|
2 | Q9WTW5 (/ISO) Q9WTW5 (/ISO) |
|
Quaternary ammonium group transmembrane transporter activity GO:0015651
Enables the transfer of quaternary ammonium groups from one side of a membrane to the other. Quaternary ammonium groups are any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups.
|
2 | Q9WTW5 (/ISO) Q9WTW5 (/ISO) |
|
Toxin transmembrane transporter activity GO:0019534
Enables the transfer of a toxin from one side of a membrane to the other. A toxin is a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.
|
2 | Q9WTW5 (/ISO) Q9WTW5 (/ISO) |
|
Transmembrane transporter activity GO:0022857
Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.
|
2 | Q5VSI5 (/IDA) Q7T2C0 (/IDA) |
|
Dopamine:sodium symporter activity GO:0005330
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dopamine(out) + Na+(out) + Cl-(out)= dopamine(in) + Na+(in) + Cl-(in).
|
1 | O88446 (/IDA) |
|
Organic cation transmembrane transporter activity GO:0015101
Enables the transfer of organic cations from one side of a membrane to the other. Organic cations are atoms or small molecules with a positive charge that contain carbon in covalent linkage.
|
1 | O75751 (/TAS) |
|
Quaternary ammonium group transmembrane transporter activity GO:0015651
Enables the transfer of quaternary ammonium groups from one side of a membrane to the other. Quaternary ammonium groups are any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups.
|
1 | O88446 (/IMP) |
|
Toxin transmembrane transporter activity GO:0019534
Enables the transfer of a toxin from one side of a membrane to the other. A toxin is a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.
|
1 | O88446 (/IDA) |
There are 13 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Organic cation transport GO:0015695
The directed movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic cations are atoms or small molecules with a positive charge which contain carbon in covalent linkage.
|
4 | O75751 (/IDA) O88446 (/IDA) Q9WTW5 (/IDA) Q9WTW5 (/IDA) |
|
Quaternary ammonium group transport GO:0015697
The directed movement into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore of quaternary ammonium compounds, any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups.
|
3 | O75751 (/IDA) Q9WTW5 (/IDA) Q9WTW5 (/IDA) |
|
Organic cation transport GO:0015695
The directed movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic cations are atoms or small molecules with a positive charge which contain carbon in covalent linkage.
|
2 | Q9WTW5 (/ISO) Q9WTW5 (/ISO) |
|
Quaternary ammonium group transport GO:0015697
The directed movement into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore of quaternary ammonium compounds, any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups.
|
2 | Q9WTW5 (/ISO) Q9WTW5 (/ISO) |
|
Monoamine transport GO:0015844
The directed movement of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
2 | Q9WTW5 (/IMP) Q9WTW5 (/IMP) |
|
Dopamine transport GO:0015872
The directed movement of dopamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
|
2 | Q9WTW5 (/ISO) Q9WTW5 (/ISO) |
|
Regulation of appetite GO:0032098
Any process which modulates appetite, the desire or physical craving for food.
|
2 | Q9WTW5 (/IMP) Q9WTW5 (/IMP) |
|
Histamine transport GO:0051608
The directed movement of histamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.
|
2 | Q9WTW5 (/IMP) Q9WTW5 (/IMP) |
|
Histamine uptake GO:0051615
The directed movement of histamine into a cell, typically presynaptic neurons or glial cells. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.
|
2 | Q9WTW5 (/IMP) Q9WTW5 (/IMP) |
|
Drug transmembrane transport GO:0006855
The process in which a drug is transported across a membrane.
|
1 | O75751 (/TAS) |
|
Organic cation transport GO:0015695
The directed movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic cations are atoms or small molecules with a positive charge which contain carbon in covalent linkage.
|
1 | O75751 (/TAS) |
|
Quaternary ammonium group transport GO:0015697
The directed movement into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore of quaternary ammonium compounds, any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups.
|
1 | O88446 (/IMP) |
|
Dopamine transport GO:0015872
The directed movement of dopamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
|
1 | O88446 (/IDA) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
3 | O75751 (/TAS) Q9WTW5 (/TAS) Q9WTW5 (/TAS) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | Q5VSI5 (/IDA) Q7T2C0 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | O75751 (/TAS) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | O75751 (/TAS) |
