The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"MFS general substrate transporter like domains
".
FunFam 145: Chromaffin granule amine transporter
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Dopamine:sodium symporter activity GO:0005330
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dopamine(out) + Na+(out) + Cl-(out)= dopamine(in) + Na+(in) + Cl-(in).
|
1 | Q9GNP0 (/IDA) |
Serotonin:sodium symporter activity GO:0005335
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: serotonin(out) + Na+(out) + Cl-(out) = serotonin(in) + Na+(in)+ Cl-(in).
|
1 | Q9GNP0 (/IDA) |
Monoamine transmembrane transporter activity GO:0008504
Enables the transfer of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), from one side of a membrane to the other.
|
1 | Q8IH57 (/IDA) |
Monoamine transmembrane transporter activity GO:0008504
Enables the transfer of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), from one side of a membrane to the other.
|
1 | Q7Z1Q0 (/ISS) |
There are 11 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Dopamine transport GO:0015872
The directed movement of dopamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
|
3 | Q86NW1 (/IMP) Q8IGS0 (/IMP) Q8IH57 (/IMP) |
Histamine transport GO:0051608
The directed movement of histamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.
|
3 | Q86NW1 (/IMP) Q8IGS0 (/IMP) Q8IH57 (/IMP) |
Positive regulation of dopaminergic neuron differentiation GO:1904340
Any process that activates or increases the frequency, rate or extent of dopaminergic neuron differentiation.
|
3 | Q86NW1 (/IMP) Q8IGS0 (/IMP) Q8IH57 (/IMP) |
Response to rotenone GO:1904647
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rotenone stimulus.
|
3 | Q86NW1 (/IMP) Q8IGS0 (/IMP) Q8IH57 (/IMP) |
Feeding behavior GO:0007631
Behavior associated with the intake of food.
|
2 | Q7Z1Q0 (/IMP) Q9GNP0 (/IMP) |
Monoamine transport GO:0015844
The directed movement of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
2 | Q7Z1Q0 (/IDA) Q8IH57 (/IDA) |
Serotonin transport GO:0006837
The directed movement of serotonin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems.
|
1 | Q9GNP0 (/IDA) |
Aminergic neurotransmitter loading into synaptic vesicle GO:0015842
The active transport of aminergic neurotransmitters into a synaptic vesicle. This import is fuelled by an electrochemical gradient across the vesicle membrane, established by the action proton pumps.
|
1 | Q8IH57 (/IDA) |
Dopamine transport GO:0015872
The directed movement of dopamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
|
1 | Q9GNP0 (/IDA) |
Dopamine biosynthetic process GO:0042416
The chemical reactions and pathways resulting in the formation of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
|
1 | Q7Z1Q0 (/IMP) |
Dopamine metabolic process GO:0042417
The chemical reactions and pathways involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
|
1 | Q9GNP0 (/IMP) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Synaptic vesicle GO:0008021
A secretory organelle, typically 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.
|
5 | Q7Z1Q0 (/IDA) Q86NW1 (/IDA) Q8IGS0 (/IDA) Q8IH57 (/IDA) Q9GNP0 (/IDA) |
Neuromuscular junction GO:0031594
The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential.
|
1 | Q8IH57 (/IDA) |