The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
MFS general substrate transporter like domains
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 111: Solute carrier family 37 member 4

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Glucose-6-phosphate transmembrane transporter activity GO:0015152
Enables the transfer of glucose-6-phosphate from one side of a membrane to the other. Glucose-6-phosphate is a monophosphorylated derivative of glucose with the phosphate group attached to C-6.
4 A0A0G2JTY3 (/IMP) O43826 (/IMP) O43826 (/IMP) Q6IRK4 (/IMP)
Glucose-6-phosphate transmembrane transporter activity GO:0015152
Enables the transfer of glucose-6-phosphate from one side of a membrane to the other. Glucose-6-phosphate is a monophosphorylated derivative of glucose with the phosphate group attached to C-6.
3 A0A1L1SUI3 (/ISO) Q9D1F9 (/ISO) Q9Z295 (/ISO)
Glucose 6-phosphate:inorganic phosphate antiporter activity GO:0061513
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose 6-phosphate(out) + inorganic phosphate(in) = glucose 6-phosphate(in) + inorganic phosphate(out).
3 A0A1L1SUI3 (/ISO) Q9D1F9 (/ISO) Q9Z295 (/ISO)
Glucose 6-phosphate:inorganic phosphate antiporter activity GO:0061513
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose 6-phosphate(out) + inorganic phosphate(in) = glucose 6-phosphate(in) + inorganic phosphate(out).
2 O43826 (/EXP) O43826 (/EXP)
Glucose 6-phosphate:inorganic phosphate antiporter activity GO:0061513
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose 6-phosphate(out) + inorganic phosphate(in) = glucose 6-phosphate(in) + inorganic phosphate(out).
2 O43826 (/IDA) O43826 (/IDA)

There are 33 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Glucose-6-phosphate transport GO:0015760
The directed movement of glucose-6-phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glucose-6-phosphate is a monophosphorylated derivative of glucose with the phosphate group attached to C-6.
7 A0A0G2JTY3 (/IMP) A0A1L1SUI3 (/IMP) O43826 (/IMP) O43826 (/IMP) Q6IRK4 (/IMP) Q9D1F9 (/IMP) Q9Z295 (/IMP)
Glucose-6-phosphate transport GO:0015760
The directed movement of glucose-6-phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glucose-6-phosphate is a monophosphorylated derivative of glucose with the phosphate group attached to C-6.
5 A0A1L1SUI3 (/IDA) O43826 (/IDA) O43826 (/IDA) Q9D1F9 (/IDA) Q9Z295 (/IDA)
Neutrophil homeostasis GO:0001780
The process of regulating the proliferation and elimination of neutrophils such that the total number of neutrophils within a whole or part of an organism is stable over time in the absence of an outside stimulus.
3 A0A1L1SUI3 (/IMP) Q9D1F9 (/IMP) Q9Z295 (/IMP)
Cytokine production GO:0001816
The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
3 A0A1L1SUI3 (/IMP) Q9D1F9 (/IMP) Q9Z295 (/IMP)
Myeloid progenitor cell differentiation GO:0002318
The process in which a precursor cell type acquires the specialized features of a myeloid progenitor cell. Myeloid progenitor cells include progenitor cells for any of the myeloid lineages.
3 A0A1L1SUI3 (/IMP) Q9D1F9 (/IMP) Q9Z295 (/IMP)
Glycogen metabolic process GO:0005977
The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages.
3 A0A1L1SUI3 (/IMP) Q9D1F9 (/IMP) Q9Z295 (/IMP)
Lactate metabolic process GO:0006089
The chemical reactions and pathways involving lactate, the anion of lactic acid.
3 A0A1L1SUI3 (/IMP) Q9D1F9 (/IMP) Q9Z295 (/IMP)
Triglyceride metabolic process GO:0006641
The chemical reactions and pathways involving triglyceride, any triester of glycerol. The three fatty acid residues may all be the same or differ in any permutation. Triglycerides are important components of plant oils, animal fats and animal plasma lipoproteins.
3 A0A1L1SUI3 (/IMP) Q9D1F9 (/IMP) Q9Z295 (/IMP)
Cellular calcium ion homeostasis GO:0006874
Any process involved in the maintenance of an internal steady state of calcium ions at the level of a cell.
3 A0A1L1SUI3 (/IMP) Q9D1F9 (/IMP) Q9Z295 (/IMP)
Steroid metabolic process GO:0008202
The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.
3 A0A1L1SUI3 (/IMP) Q9D1F9 (/IMP) Q9Z295 (/IMP)
Response to organic cyclic compound GO:0014070
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
3 A0A1L1SUI3 (/ISO) Q9D1F9 (/ISO) Q9Z295 (/ISO)
Glucose-6-phosphate transport GO:0015760
The directed movement of glucose-6-phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glucose-6-phosphate is a monophosphorylated derivative of glucose with the phosphate group attached to C-6.
3 A0A1L1SUI3 (/IGI) Q9D1F9 (/IGI) Q9Z295 (/IGI)
Glucose-6-phosphate transport GO:0015760
The directed movement of glucose-6-phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glucose-6-phosphate is a monophosphorylated derivative of glucose with the phosphate group attached to C-6.
3 A0A1L1SUI3 (/ISO) Q9D1F9 (/ISO) Q9Z295 (/ISO)
Neutrophil chemotaxis GO:0030593
The directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.
3 A0A1L1SUI3 (/IMP) Q9D1F9 (/IMP) Q9Z295 (/IMP)
Negative regulation of chemokine production GO:0032682
Any process that stops, prevents, or reduces the frequency, rate, or extent of chemokine production.
3 A0A1L1SUI3 (/IMP) Q9D1F9 (/IMP) Q9Z295 (/IMP)
Post-embryonic hemopoiesis GO:0035166
The stages of blood cell formation that take place after completion of embryonic development.
3 A0A1L1SUI3 (/IMP) Q9D1F9 (/IMP) Q9Z295 (/IMP)
Phosphate ion transmembrane transport GO:0035435
The process in which a phosphate is transported across a membrane.
3 A0A1L1SUI3 (/ISO) Q9D1F9 (/ISO) Q9Z295 (/ISO)
Glucose homeostasis GO:0042593
Any process involved in the maintenance of an internal steady state of glucose within an organism or cell.
3 A0A1L1SUI3 (/IMP) Q9D1F9 (/IMP) Q9Z295 (/IMP)
Glucose homeostasis GO:0042593
Any process involved in the maintenance of an internal steady state of glucose within an organism or cell.
3 A0A1L1SUI3 (/ISO) Q9D1F9 (/ISO) Q9Z295 (/ISO)
Cholesterol homeostasis GO:0042632
Any process involved in the maintenance of an internal steady state of cholesterol within an organism or cell.
3 A0A1L1SUI3 (/IMP) Q9D1F9 (/IMP) Q9Z295 (/IMP)
Positive regulation of catalytic activity GO:0043085
Any process that activates or increases the activity of an enzyme.
3 A0A1L1SUI3 (/IMP) Q9D1F9 (/IMP) Q9Z295 (/IMP)
Respiratory burst GO:0045730
A phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.
3 A0A1L1SUI3 (/IMP) Q9D1F9 (/IMP) Q9Z295 (/IMP)
Response to steroid hormone GO:0048545
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus.
3 E9QCU6 (/IEP) F1R0A9 (/IEP) Q6NY67 (/IEP)
Glycogen metabolic process GO:0005977
The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages.
2 A0A0G2JTY3 (/NAS) Q6IRK4 (/NAS)
Glucose metabolic process GO:0006006
The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides.
2 O43826 (/NAS) O43826 (/NAS)
Gluconeogenesis GO:0006094
The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.
2 O43826 (/TAS) O43826 (/TAS)
Response to nutrient GO:0007584
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus.
2 A0A0G2JTY3 (/IEP) Q6IRK4 (/IEP)
Response to glucose GO:0009749
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.
2 A0A0G2JTY3 (/IEP) Q6IRK4 (/IEP)
Response to organic cyclic compound GO:0014070
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
2 A0A0G2JTY3 (/IDA) Q6IRK4 (/IDA)
Glucose-6-phosphate transport GO:0015760
The directed movement of glucose-6-phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glucose-6-phosphate is a monophosphorylated derivative of glucose with the phosphate group attached to C-6.
2 O43826 (/NAS) O43826 (/NAS)
Phosphate ion transmembrane transport GO:0035435
The process in which a phosphate is transported across a membrane.
2 O43826 (/IDA) O43826 (/IDA)
Glucose homeostasis GO:0042593
Any process involved in the maintenance of an internal steady state of glucose within an organism or cell.
2 Q6IRK4 (/ISS) Q9D1F9 (/ISS)
Glucose-6-phosphate transport GO:0015760
The directed movement of glucose-6-phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glucose-6-phosphate is a monophosphorylated derivative of glucose with the phosphate group attached to C-6.
1 Q6IRK4 (/ISS)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
4 A0A0G2JTY3 (/NAS) O43826 (/NAS) O43826 (/NAS) Q6IRK4 (/NAS)
Integral component of endoplasmic reticulum membrane GO:0030176
The component of the endoplasmic reticulum membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
3 A0A1L1SUI3 (/ISO) Q9D1F9 (/ISO) Q9Z295 (/ISO)
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
3 A0A1L1SUI3 (/ISO) Q9D1F9 (/ISO) Q9Z295 (/ISO)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
2 O43826 (/NAS) O43826 (/NAS)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
2 O43826 (/TAS) O43826 (/TAS)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
2 O43826 (/HDA) O43826 (/HDA)
Integral component of endoplasmic reticulum membrane GO:0030176
The component of the endoplasmic reticulum membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 O43826 (/IDA) O43826 (/IDA)
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
2 A0A0G2JTY3 (/IDA) Q6IRK4 (/IDA)
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