CATH Superfamily 1.20.1250.10
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 4: Kit ligand
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
7 | P20826 (/IPI) P21583 (/IPI) P21583 (/IPI) P21583 (/IPI) P21583 (/IPI) P21583 (/IPI) P21583 (/IPI) |
|
Stem cell factor receptor binding GO:0005173
Interacting selectively and non-covalently with the stem cell factor receptor (SCFR), a type III transmembrane kinase receptor.
|
6 | P21583 (/TAS) P21583 (/TAS) P21583 (/TAS) P21583 (/TAS) P21583 (/TAS) P21583 (/TAS) |
|
Cytokine activity GO:0005125
Functions to control the survival, growth, differentiation and effector function of tissues and cells.
|
1 | P20826 (/IDA) |
|
Stem cell factor receptor binding GO:0005173
Interacting selectively and non-covalently with the stem cell factor receptor (SCFR), a type III transmembrane kinase receptor.
|
1 | P20826 (/IDA) |
There are 25 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
8 | P20826 (/IDA) P21581 (/IDA) P21583 (/IDA) P21583 (/IDA) P21583 (/IDA) P21583 (/IDA) P21583 (/IDA) P21583 (/IDA) |
|
MAPK cascade GO:0000165
An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain an additional tiers: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell.
|
6 | P21583 (/TAS) P21583 (/TAS) P21583 (/TAS) P21583 (/TAS) P21583 (/TAS) P21583 (/TAS) |
|
Male gonad development GO:0008584
The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure.
|
6 | P21583 (/IEP) P21583 (/IEP) P21583 (/IEP) P21583 (/IEP) P21583 (/IEP) P21583 (/IEP) |
|
Embryonic hemopoiesis GO:0035162
The stages of blood cell formation that take place within the embryo.
|
6 | P21583 (/IDA) P21583 (/IDA) P21583 (/IDA) P21583 (/IDA) P21583 (/IDA) P21583 (/IDA) |
|
Positive regulation of protein kinase B signaling GO:0051897
Any process that activates or increases the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.
|
6 | P21583 (/TAS) P21583 (/TAS) P21583 (/TAS) P21583 (/TAS) P21583 (/TAS) P21583 (/TAS) |
|
Positive regulation of hematopoietic progenitor cell differentiation GO:1901534
Any process that activates or increases the frequency, rate or extent of hematopoietic progenitor cell differentiation.
|
6 | P21583 (/TAS) P21583 (/TAS) P21583 (/TAS) P21583 (/TAS) P21583 (/TAS) P21583 (/TAS) |
|
Ovarian follicle development GO:0001541
The process whose specific outcome is the progression of the ovarian follicle over time, from its formation to the mature structure.
|
1 | P21581 (/IDA) |
|
Ovarian follicle development GO:0001541
The process whose specific outcome is the progression of the ovarian follicle over time, from its formation to the mature structure.
|
1 | P20826 (/ISO) |
|
Neural crest cell migration GO:0001755
The characteristic movement of cells from the dorsal ridge of the neural tube to a variety of locations in a vertebrate embryo.
|
1 | P20826 (/IDA) |
|
Positive regulation of leukocyte migration GO:0002687
Any process that activates or increases the frequency, rate, or extent of leukocyte migration.
|
1 | P20826 (/IDA) |
|
Positive regulation of myeloid leukocyte differentiation GO:0002763
Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte differentiation.
|
1 | P20826 (/IGI) |
|
Germ cell development GO:0007281
The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism.
|
1 | P20826 (/TAS) |
|
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
1 | P20826 (/IGI) |
|
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
1 | P20826 (/ISO) |
|
Negative regulation of mast cell apoptotic process GO:0033026
Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell apoptotic process.
|
1 | P20826 (/IDA) |
|
Embryonic hemopoiesis GO:0035162
The stages of blood cell formation that take place within the embryo.
|
1 | P20826 (/ISO) |
|
Ectopic germ cell programmed cell death GO:0035234
Programmed cell death of an errant germ line cell that is outside the normal migratory path or ectopic to the gonad. This is an important mechanism of regulating germ cell survival within the embryo.
|
1 | P20826 (/IMP) |
|
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
|
1 | P20826 (/IGI) |
|
Positive regulation of MAP kinase activity GO:0043406
Any process that activates or increases the frequency, rate or extent of MAP kinase activity.
|
1 | P20826 (/IGI) |
|
Positive regulation of melanocyte differentiation GO:0045636
Any process that activates or increases the frequency, rate or extent of melanocyte differentiation.
|
1 | P20826 (/IDA) |
|
Positive regulation of Ras protein signal transduction GO:0046579
Any process that activates or increases the frequency, rate or extent of Ras protein signal transduction.
|
1 | P20826 (/IDA) |
|
Positive regulation of peptidyl-tyrosine phosphorylation GO:0050731
Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.
|
1 | P20826 (/IDA) |
|
Positive regulation of mast cell proliferation GO:0070668
Any process that activates or increases the rate or extent of mast cell proliferation.
|
1 | P20826 (/IDA) |
|
Extrinsic apoptotic signaling pathway in absence of ligand GO:0097192
A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with withdrawal of a ligand from a cell surface receptor, and ends when the execution phase of apoptosis is triggered.
|
1 | P20826 (/IDA) |
|
Positive regulation of hematopoietic stem cell proliferation GO:1902035
Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell proliferation.
|
1 | P20826 (/IDA) |
There are 17 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
13 |
P20826 (/ISS)
P21581 (/ISS)
P79169 (/ISS)
P79368 (/ISS)
Q06220 (/ISS)
Q09108 (/ISS)
Q09108 (/ISS)
Q28132 (/ISS)
Q29030 (/ISS)
Q90314 (/ISS)
(3 more) |
|
Lamellipodium GO:0030027
A thin sheetlike process extended by the leading edge of a migrating cell or extending cell process; contains a dense meshwork of actin filaments.
|
13 |
P20826 (/ISS)
P21581 (/ISS)
P79169 (/ISS)
P79368 (/ISS)
Q06220 (/ISS)
Q09108 (/ISS)
Q09108 (/ISS)
Q28132 (/ISS)
Q29030 (/ISS)
Q90314 (/ISS)
(3 more) |
|
Filopodium GO:0030175
Thin, stiff, actin-based protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal or dendritic growth cone, or a dendritic shaft.
|
13 |
P20826 (/ISS)
P21581 (/ISS)
P79169 (/ISS)
P79368 (/ISS)
Q06220 (/ISS)
Q09108 (/ISS)
Q09108 (/ISS)
Q28132 (/ISS)
Q29030 (/ISS)
Q90314 (/ISS)
(3 more) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
12 |
P21581 (/ISS)
P79169 (/ISS)
P79368 (/ISS)
Q06220 (/ISS)
Q09108 (/ISS)
Q09108 (/ISS)
Q28132 (/ISS)
Q29030 (/ISS)
Q90314 (/ISS)
Q95M19 (/ISS)
(2 more) |
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
7 | P20826 (/TAS) P21583 (/TAS) P21583 (/TAS) P21583 (/TAS) P21583 (/TAS) P21583 (/TAS) P21583 (/TAS) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
7 | P20826 (/IDA) P21583 (/IDA) P21583 (/IDA) P21583 (/IDA) P21583 (/IDA) P21583 (/IDA) P21583 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
6 | P21583 (/IDA) P21583 (/IDA) P21583 (/IDA) P21583 (/IDA) P21583 (/IDA) P21583 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
6 | P21583 (/NAS) P21583 (/NAS) P21583 (/NAS) P21583 (/NAS) P21583 (/NAS) P21583 (/NAS) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
6 | P21583 (/TAS) P21583 (/TAS) P21583 (/TAS) P21583 (/TAS) P21583 (/TAS) P21583 (/TAS) |
|
Lamellipodium GO:0030027
A thin sheetlike process extended by the leading edge of a migrating cell or extending cell process; contains a dense meshwork of actin filaments.
|
6 | P21583 (/IDA) P21583 (/IDA) P21583 (/IDA) P21583 (/IDA) P21583 (/IDA) P21583 (/IDA) |
|
Filopodium GO:0030175
Thin, stiff, actin-based protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal or dendritic growth cone, or a dendritic shaft.
|
6 | P21583 (/IDA) P21583 (/IDA) P21583 (/IDA) P21583 (/IDA) P21583 (/IDA) P21583 (/IDA) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
1 | P20826 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | P20826 (/ISO) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | P20826 (/ISO) |
|
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | P20826 (/IDA) |
|
Lamellipodium GO:0030027
A thin sheetlike process extended by the leading edge of a migrating cell or extending cell process; contains a dense meshwork of actin filaments.
|
1 | P20826 (/ISO) |
|
Filopodium GO:0030175
Thin, stiff, actin-based protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal or dendritic growth cone, or a dendritic shaft.
|
1 | P20826 (/ISO) |
