The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Growth hormone

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 11 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Growth hormone receptor binding GO:0005131
Interacting selectively and non-covalently with the growth hormone receptor.
23 A4GX95 (/IMP) A4GX95 (/IMP) A4GX95 (/IMP) A4GX95 (/IMP) A4GX95 (/IMP) A4LAP1 (/IMP) B0FPG4 (/IMP) B0FPG4 (/IMP) B0FPG6 (/IMP) B0FPG6 (/IMP)
(13 more)
Cysteine-type endopeptidase activity involved in apoptotic process GO:0097153
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the apoptotic process.
16 E5Q3H3 (/IDA) H6ULW9 (/IDA) H6ULX0 (/IDA) H6ULX1 (/IDA) H6ULX7 (/IDA) H6UQ57 (/IDA) H6UQ58 (/IDA) H6UQ60 (/IDA) H6UQ61 (/IDA) H6UQ62 (/IDA)
(6 more)
Cysteine-type endopeptidase activity involved in apoptotic process GO:0097153
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the apoptotic process.
16 A0A087RIM6 (/ISS) A0A093NDD2 (/ISS) B8XY22 (/ISS) G1N9C6 (/ISS) G3LUM5 (/ISS) G3LUM5 (/ISS) P11228 (/ISS) P11228 (/ISS) P22077 (/ISS) Q549W9 (/ISS)
(6 more)
Growth hormone receptor binding GO:0005131
Interacting selectively and non-covalently with the growth hormone receptor.
6 P01246 (/IDA) P01246 (/IDA) P01246 (/IDA) P01246 (/IDA) P01246 (/IDA) P01246 (/IDA)
Growth hormone receptor binding GO:0005131
Interacting selectively and non-covalently with the growth hormone receptor.
2 P06880 (/IPI) P06880 (/IPI)
Growth hormone receptor binding GO:0005131
Interacting selectively and non-covalently with the growth hormone receptor.
2 P06880 (/ISO) P06880 (/ISO)
Hormone activity GO:0005179
The action characteristic of a hormone, any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. The term was originally applied to agents with a stimulatory physiological action in vertebrate animals (as opposed to a chalone, which has a depressant action). Usage is now extended to regulatory compounds in lower animals and plants, and to synthetic substances having comparable effects; all bind receptors and trigger some biological process.
2 P01244 (/IDA) P01244 (/IDA)
Hormone activity GO:0005179
The action characteristic of a hormone, any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. The term was originally applied to agents with a stimulatory physiological action in vertebrate animals (as opposed to a chalone, which has a depressant action). Usage is now extended to regulatory compounds in lower animals and plants, and to synthetic substances having comparable effects; all bind receptors and trigger some biological process.
2 P06880 (/ISO) P06880 (/ISO)
Glucose-6-phosphatase activity GO:0004346
Catalysis of the reaction: D-glucopyranose 6-phosphate + H2O = D-glucose + phosphate. D-glucopyranose is also known as D-glucose 6-phosphate.
1 A7UIY9 (/IMP)
Growth hormone receptor binding GO:0005131
Interacting selectively and non-covalently with the growth hormone receptor.
1 Q2PQK2 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 P08998 (/IPI)

There are 97 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Insulin secretion GO:0030073
The regulated release of proinsulin from secretory granules accompanied by cleavage of proinsulin to form mature insulin. In vertebrates, insulin is secreted from B granules in the B cells of the vertebrate pancreas and from insulin-producing cells in insects.
62 A0FJ27 (/ISS) A1Z074 (/ISS) A1Z074 (/ISS) A1Z074 (/ISS) A1Z074 (/ISS) A1Z074 (/ISS) A1Z074 (/ISS) A4GX98 (/ISS) A5YVX0 (/ISS) A5YVX0 (/ISS)
(52 more)
Magnesium ion homeostasis GO:0010960
Any process involved in the maintenance of an internal steady state of magnesium ions within an organism or cell.
40 A0FJ27 (/IMP) A4GX92 (/IMP) A4GX93 (/IMP) A4GX94 (/IMP) A7UIY9 (/IMP) C8CP44 (/IMP) G3CI04 (/IMP) P67930 (/IMP) P67930 (/IMP) P67930 (/IMP)
(30 more)
Positive regulation of superoxide anion generation GO:0032930
Any process that activates or increases the frequency, rate or extent of enzymatic generation of superoxide by a cell.
40 A0FJ27 (/IMP) A4GX92 (/IMP) A4GX93 (/IMP) A4GX94 (/IMP) A7UIY9 (/IMP) C8CP44 (/IMP) G3CI04 (/IMP) P67930 (/IMP) P67930 (/IMP) P67930 (/IMP)
(30 more)
Hyperosmotic salinity response GO:0042538
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
40 A0FJ27 (/IMP) A4GX92 (/IMP) A4GX93 (/IMP) A4GX94 (/IMP) A7UIY9 (/IMP) C8CP44 (/IMP) G3CI04 (/IMP) P67930 (/IMP) P67930 (/IMP) P67930 (/IMP)
(30 more)
Calcium ion homeostasis GO:0055074
Any process involved in the maintenance of an internal steady state of calcium ions within an organism or cell.
40 A0FJ27 (/IMP) A4GX92 (/IMP) A4GX93 (/IMP) A4GX94 (/IMP) A7UIY9 (/IMP) C8CP44 (/IMP) G3CI04 (/IMP) P67930 (/IMP) P67930 (/IMP) P67930 (/IMP)
(30 more)
Sodium ion homeostasis GO:0055078
Any process involved in the maintenance of an internal steady state of sodium ions within an organism or cell.
40 A0FJ27 (/IMP) A4GX92 (/IMP) A4GX93 (/IMP) A4GX94 (/IMP) A7UIY9 (/IMP) C8CP44 (/IMP) G3CI04 (/IMP) P67930 (/IMP) P67930 (/IMP) P67930 (/IMP)
(30 more)
Positive regulation of sodium:potassium-exchanging ATPase activity GO:1903408
Any process that activates or increases the frequency, rate or extent of sodium:potassium-exchanging ATPase activity.
40 A0FJ27 (/IMP) A4GX92 (/IMP) A4GX93 (/IMP) A4GX94 (/IMP) A7UIY9 (/IMP) C8CP44 (/IMP) G3CI04 (/IMP) P67930 (/IMP) P67930 (/IMP) P67930 (/IMP)
(30 more)
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
39 A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4LAP1 (/IDA) B0FPG4 (/IDA) B0FPG4 (/IDA) B0FPG6 (/IDA) B0FPG6 (/IDA)
(29 more)
Response to food GO:0032094
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a food stimulus; food is anything which, when taken into the body, serves to nourish or build up the tissues or to supply body heat.
25 A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4LAP1 (/IDA) B0FPG4 (/IDA) B0FPG4 (/IDA) B0FPG6 (/IDA) B0FPG6 (/IDA)
(15 more)
Cell population proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
23 A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4LAP1 (/IDA) B0FPG4 (/IDA) B0FPG4 (/IDA) B0FPG6 (/IDA) B0FPG6 (/IDA)
(13 more)
Protein secretion GO:0009306
The controlled release of proteins from a cell.
23 A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4LAP1 (/IDA) B0FPG4 (/IDA) B0FPG4 (/IDA) B0FPG6 (/IDA) B0FPG6 (/IDA)
(13 more)
Positive regulation of peptidyl-threonine phosphorylation GO:0010800
Any process that increases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.
23 A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4LAP1 (/IDA) B0FPG4 (/IDA) B0FPG4 (/IDA) B0FPG6 (/IDA) B0FPG6 (/IDA)
(13 more)
Positive regulation of triglyceride biosynthetic process GO:0010867
Any process that increases the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol.
23 A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4LAP1 (/IDA) B0FPG4 (/IDA) B0FPG4 (/IDA) B0FPG6 (/IDA) B0FPG6 (/IDA)
(13 more)
Insulin secretion GO:0030073
The regulated release of proinsulin from secretory granules accompanied by cleavage of proinsulin to form mature insulin. In vertebrates, insulin is secreted from B granules in the B cells of the vertebrate pancreas and from insulin-producing cells in insects.
23 A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4LAP1 (/IDA) B0FPG4 (/IDA) B0FPG4 (/IDA) B0FPG6 (/IDA) B0FPG6 (/IDA)
(13 more)
Response to nutrient levels GO:0031667
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.
23 A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4LAP1 (/IDA) B0FPG4 (/IDA) B0FPG4 (/IDA) B0FPG6 (/IDA) B0FPG6 (/IDA)
(13 more)
Negative regulation of urine volume GO:0035811
Any process that decreases the amount of urine excreted from the body over a unit of time.
23 A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4LAP1 (/IDA) B0FPG4 (/IDA) B0FPG4 (/IDA) B0FPG6 (/IDA) B0FPG6 (/IDA)
(13 more)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
23 A4GX95 (/IMP) A4GX95 (/IMP) A4GX95 (/IMP) A4GX95 (/IMP) A4GX95 (/IMP) A4LAP1 (/IMP) B0FPG4 (/IMP) B0FPG4 (/IMP) B0FPG6 (/IMP) B0FPG6 (/IMP)
(13 more)
Positive regulation of cholesterol biosynthetic process GO:0045542
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.
23 A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4LAP1 (/IDA) B0FPG4 (/IDA) B0FPG4 (/IDA) B0FPG6 (/IDA) B0FPG6 (/IDA)
(13 more)
Negative regulation of fatty acid biosynthetic process GO:0045717
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids.
23 A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4LAP1 (/IDA) B0FPG4 (/IDA) B0FPG4 (/IDA) B0FPG6 (/IDA) B0FPG6 (/IDA)
(13 more)
Positive regulation of fatty acid biosynthetic process GO:0045723
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids.
23 A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4LAP1 (/IDA) B0FPG4 (/IDA) B0FPG4 (/IDA) B0FPG6 (/IDA) B0FPG6 (/IDA)
(13 more)
Positive regulation of peptidyl-tyrosine phosphorylation GO:0050731
Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.
23 A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4LAP1 (/IDA) B0FPG4 (/IDA) B0FPG4 (/IDA) B0FPG6 (/IDA) B0FPG6 (/IDA)
(13 more)
Positive regulation of lipid catabolic process GO:0050996
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids.
23 A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4LAP1 (/IDA) B0FPG4 (/IDA) B0FPG4 (/IDA) B0FPG6 (/IDA) B0FPG6 (/IDA)
(13 more)
Renal sodium ion absorption GO:0070294
A renal system process in which sodium ions are taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.
23 A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4LAP1 (/IDA) B0FPG4 (/IDA) B0FPG4 (/IDA) B0FPG6 (/IDA) B0FPG6 (/IDA)
(13 more)
Positive regulation of phospholipid biosynthetic process GO:0071073
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids.
23 A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4LAP1 (/IDA) B0FPG4 (/IDA) B0FPG4 (/IDA) B0FPG6 (/IDA) B0FPG6 (/IDA)
(13 more)
Positive regulation of diacylglycerol biosynthetic process GO:1900482
Any process that activates or increases the frequency, rate or extent of diacylglycerol biosynthetic process.
23 A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4LAP1 (/IDA) B0FPG4 (/IDA) B0FPG4 (/IDA) B0FPG6 (/IDA) B0FPG6 (/IDA)
(13 more)
Negative regulation of protein acetylation GO:1901984
Any process that stops, prevents or reduces the frequency, rate or extent of protein acetylation.
23 A4GX95 (/IMP) A4GX95 (/IMP) A4GX95 (/IMP) A4GX95 (/IMP) A4GX95 (/IMP) A4LAP1 (/IMP) B0FPG4 (/IMP) B0FPG4 (/IMP) B0FPG6 (/IMP) B0FPG6 (/IMP)
(13 more)
Positive regulation of lactation GO:1903489
Any process that activates or increases the frequency, rate or extent of lactation.
23 A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4LAP1 (/IDA) B0FPG4 (/IDA) B0FPG4 (/IDA) B0FPG6 (/IDA) B0FPG6 (/IDA)
(13 more)
Response to L-arginine GO:1903576
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-arginine stimulus.
23 A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4LAP1 (/IDA) B0FPG4 (/IDA) B0FPG4 (/IDA) B0FPG6 (/IDA) B0FPG6 (/IDA)
(13 more)
Positive regulation of feeding behavior GO:2000253
Any process that activates or increases the frequency, rate or extent of feeding behavior.
23 A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4LAP1 (/IDA) B0FPG4 (/IDA) B0FPG4 (/IDA) B0FPG6 (/IDA) B0FPG6 (/IDA)
(13 more)
Positive regulation of steroid hormone secretion GO:2000833
Any process that activates or increases the frequency, rate or extent of steroid hormone secretion.
23 A4GX95 (/IMP) A4GX95 (/IMP) A4GX95 (/IMP) A4GX95 (/IMP) A4GX95 (/IMP) A4LAP1 (/IMP) B0FPG4 (/IMP) B0FPG4 (/IMP) B0FPG6 (/IMP) B0FPG6 (/IMP)
(13 more)
Negative regulation of testosterone secretion GO:2000844
Any process that stops, prevents or reduces the frequency, rate or extent of testosterone secretion.
23 A4GX95 (/IMP) A4GX95 (/IMP) A4GX95 (/IMP) A4GX95 (/IMP) A4GX95 (/IMP) A4LAP1 (/IMP) B0FPG4 (/IMP) B0FPG4 (/IMP) B0FPG6 (/IMP) B0FPG6 (/IMP)
(13 more)
Positive regulation of aldosterone secretion GO:2000860
Any process that activates or increases the frequency, rate or extent of aldosterone secretion.
23 A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4LAP1 (/IDA) B0FPG4 (/IDA) B0FPG4 (/IDA) B0FPG6 (/IDA) B0FPG6 (/IDA)
(13 more)
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
17 A0A087RIM6 (/ISS) A0A093NDD2 (/ISS) B8XY22 (/ISS) G1N9C6 (/ISS) G3LUM5 (/ISS) G3LUM5 (/ISS) P11228 (/ISS) P11228 (/ISS) P22077 (/ISS) Q2PQK2 (/ISS)
(7 more)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
16 E5Q3H3 (/IDA) H6ULW9 (/IDA) H6ULX0 (/IDA) H6ULX1 (/IDA) H6ULX7 (/IDA) H6UQ57 (/IDA) H6UQ58 (/IDA) H6UQ60 (/IDA) H6UQ61 (/IDA) H6UQ62 (/IDA)
(6 more)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
16 A0A087RIM6 (/ISS) A0A093NDD2 (/ISS) B8XY22 (/ISS) G1N9C6 (/ISS) G3LUM5 (/ISS) G3LUM5 (/ISS) P11228 (/ISS) P11228 (/ISS) P22077 (/ISS) Q549W9 (/ISS)
(6 more)
Oviduct epithelium development GO:0035846
The progression of the oviduct epithelium over time from its initial formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism. The oviduct epithelium is the specialized epithelium that lines the oviduct.
16 E5Q3H3 (/IDA) H6ULW9 (/IDA) H6ULX0 (/IDA) H6ULX1 (/IDA) H6ULX7 (/IDA) H6UQ57 (/IDA) H6UQ58 (/IDA) H6UQ60 (/IDA) H6UQ61 (/IDA) H6UQ62 (/IDA)
(6 more)
Oviduct epithelium development GO:0035846
The progression of the oviduct epithelium over time from its initial formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism. The oviduct epithelium is the specialized epithelium that lines the oviduct.
16 A0A087RIM6 (/ISS) A0A093NDD2 (/ISS) B8XY22 (/ISS) G1N9C6 (/ISS) G3LUM5 (/ISS) G3LUM5 (/ISS) P11228 (/ISS) P11228 (/ISS) P22077 (/ISS) Q549W9 (/ISS)
(6 more)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
16 E5Q3H3 (/IDA) H6ULW9 (/IDA) H6ULX0 (/IDA) H6ULX1 (/IDA) H6ULX7 (/IDA) H6UQ57 (/IDA) H6UQ58 (/IDA) H6UQ60 (/IDA) H6UQ61 (/IDA) H6UQ62 (/IDA)
(6 more)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
16 A0A087RIM6 (/ISS) A0A093NDD2 (/ISS) B8XY22 (/ISS) G1N9C6 (/ISS) G3LUM5 (/ISS) G3LUM5 (/ISS) P11228 (/ISS) P11228 (/ISS) P22077 (/ISS) Q549W9 (/ISS)
(6 more)
Positive regulation of superoxide anion generation GO:0032930
Any process that activates or increases the frequency, rate or extent of enzymatic generation of superoxide by a cell.
10 A4GX95 (/ISS) A4GX95 (/ISS) A4GX95 (/ISS) A4GX95 (/ISS) A4GX95 (/ISS) Q19AP0 (/ISS) Q19AP0 (/ISS) Q19AP0 (/ISS) Q19AP0 (/ISS) Q19AP0 (/ISS)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
6 P01246 (/IMP) P01246 (/IMP) P01246 (/IMP) P01246 (/IMP) P01246 (/IMP) P01246 (/IMP)
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
6 P01246 (/IMP) P01246 (/IMP) P01246 (/IMP) P01246 (/IMP) P01246 (/IMP) P01246 (/IMP)
Negative regulation of plasminogen activation GO:0010757
Any process that decreases the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin.
6 P01246 (/IMP) P01246 (/IMP) P01246 (/IMP) P01246 (/IMP) P01246 (/IMP) P01246 (/IMP)
Positive regulation of TOR signaling GO:0032008
Any process that activates or increases the frequency, rate or extent of TOR signaling.
6 P01246 (/IMP) P01246 (/IMP) P01246 (/IMP) P01246 (/IMP) P01246 (/IMP) P01246 (/IMP)
Regulation of intracellular steroid hormone receptor signaling pathway GO:0033143
Any process that modulates the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway.
6 P01246 (/IDA) P01246 (/IDA) P01246 (/IDA) P01246 (/IDA) P01246 (/IDA) P01246 (/IDA)
Positive regulation of MAPK cascade GO:0043410
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade.
6 P01246 (/IMP) P01246 (/IMP) P01246 (/IMP) P01246 (/IMP) P01246 (/IMP) P01246 (/IMP)
Positive regulation of lactation GO:1903489
Any process that activates or increases the frequency, rate or extent of lactation.
6 P01246 (/IMP) P01246 (/IMP) P01246 (/IMP) P01246 (/IMP) P01246 (/IMP) P01246 (/IMP)
Positive regulation of cytoplasmic translation GO:2000767
Any process that activates or increases the frequency, rate or extent of cytoplasmic translation.
6 P01246 (/IMP) P01246 (/IMP) P01246 (/IMP) P01246 (/IMP) P01246 (/IMP) P01246 (/IMP)
Positive regulation of protein phosphorylation GO:0001934
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
3 P01248 (/IDA) P01248 (/IDA) P01248 (/IDA)
Positive regulation of tyrosine phosphorylation of STAT protein GO:0042531
Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein.
3 P01248 (/IDA) P01248 (/IDA) P01248 (/IDA)
Growth hormone receptor signaling pathway GO:0060396
The series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand.
3 P01248 (/IDA) P01248 (/IDA) P01248 (/IDA)
Neuroblast proliferation GO:0007405
The expansion of a neuroblast population by cell division. A neuroblast is any cell that will divide and give rise to a neuron.
2 P01244 (/IDA) P01244 (/IDA)
Neuroblast proliferation GO:0007405
The expansion of a neuroblast population by cell division. A neuroblast is any cell that will divide and give rise to a neuron.
2 P06880 (/ISO) P06880 (/ISO)
Female pregnancy GO:0007565
The set of physiological processes that allow an embryo or foetus to develop within the body of a female animal. It covers the time from fertilization of a female ovum by a male spermatozoon until birth.
2 P01244 (/IEP) P01244 (/IEP)
Response to light stimulus GO:0009416
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.
2 P01244 (/IDA) P01244 (/IDA)
Response to light stimulus GO:0009416
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.
2 P06880 (/ISO) P06880 (/ISO)
Positive regulation of glucose transmembrane transport GO:0010828
Any process that increases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 P06880 (/ISO) P06880 (/ISO)
Response to estradiol GO:0032355
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.
2 P01244 (/IEP) P01244 (/IEP)
Cellular response to insulin stimulus GO:0032869
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
2 P06880 (/IDA) P06880 (/IDA)
Regulation of intracellular steroid hormone receptor signaling pathway GO:0033143
Any process that modulates the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway.
2 P06880 (/ISO) P06880 (/ISO)
Response to cytokine GO:0034097
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.
2 P01244 (/IEP) P01244 (/IEP)
Positive regulation of multicellular organism growth GO:0040018
Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size.
2 P06880 (/IGI) P06880 (/IGI)
Response to peptide hormone GO:0043434
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals.
2 P01244 (/IEP) P01244 (/IEP)
Positive regulation of growth GO:0045927
Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism.
2 P01244 (/IMP) P01244 (/IMP)
Positive regulation of growth GO:0045927
Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism.
2 P06880 (/ISO) P06880 (/ISO)
Lung alveolus development GO:0048286
The process whose specific outcome is the progression of the alveolus over time, from its formation to the mature structure. The alveolus is a sac for holding air in the lungs; formed by the terminal dilation of air passageways.
2 P01244 (/IMP) P01244 (/IMP)
Lung alveolus development GO:0048286
The process whose specific outcome is the progression of the alveolus over time, from its formation to the mature structure. The alveolus is a sac for holding air in the lungs; formed by the terminal dilation of air passageways.
2 P06880 (/ISO) P06880 (/ISO)
Animal organ development GO:0048513
Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
2 P01244 (/IEP) P01244 (/IEP)
Positive regulation of neurogenesis GO:0050769
Any process that activates or increases the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system.
2 P01244 (/IDA) P01244 (/IDA)
Positive regulation of neurogenesis GO:0050769
Any process that activates or increases the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system.
2 P06880 (/ISO) P06880 (/ISO)
Cellular response to alkaline pH GO:0071469
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH > 7. pH is a measure of the acidity or basicity of an aqueous solution.
2 P01244 (/IEP) P01244 (/IEP)
Positive regulation of steroid hormone biosynthetic process GO:0090031
Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones.
2 P01244 (/IDA) P01244 (/IDA)
Positive regulation of steroid hormone biosynthetic process GO:0090031
Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones.
2 P06880 (/ISO) P06880 (/ISO)
Cellular response to thyroid hormone stimulus GO:0097067
A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroid hormone stimulus.
2 P01244 (/IEP) P01244 (/IEP)
Negative regulation of neuron death GO:1901215
Any process that stops, prevents or reduces the frequency, rate or extent of neuron death.
2 P01244 (/IDA) P01244 (/IDA)
Negative regulation of neuron death GO:1901215
Any process that stops, prevents or reduces the frequency, rate or extent of neuron death.
2 P06880 (/ISO) P06880 (/ISO)
Cell population proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
1 Q2PQK2 (/ISS)
Protein secretion GO:0009306
The controlled release of proteins from a cell.
1 Q2PQK2 (/ISS)
Positive regulation of peptidyl-threonine phosphorylation GO:0010800
Any process that increases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.
1 Q2PQK2 (/ISS)
Positive regulation of triglyceride biosynthetic process GO:0010867
Any process that increases the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol.
1 Q2PQK2 (/ISS)
Response to nutrient levels GO:0031667
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.
1 Q2PQK2 (/ISS)
Response to food GO:0032094
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a food stimulus; food is anything which, when taken into the body, serves to nourish or build up the tissues or to supply body heat.
1 Q2PQK2 (/ISS)
Negative regulation of urine volume GO:0035811
Any process that decreases the amount of urine excreted from the body over a unit of time.
1 Q2PQK2 (/ISS)
Positive regulation of cholesterol biosynthetic process GO:0045542
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.
1 Q2PQK2 (/ISS)
Negative regulation of fatty acid biosynthetic process GO:0045717
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids.
1 Q2PQK2 (/ISS)
Positive regulation of fatty acid biosynthetic process GO:0045723
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids.
1 Q2PQK2 (/ISS)
Regulation of defense response to virus by host GO:0050691
Any host process that modulates the frequency, rate, or extent of the antiviral response of a host cell or organism.
1 P08998 (/IMP)
Positive regulation of peptidyl-tyrosine phosphorylation GO:0050731
Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.
1 Q2PQK2 (/ISS)
Renal sodium ion absorption GO:0070294
A renal system process in which sodium ions are taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.
1 Q2PQK2 (/ISS)
Positive regulation of phospholipid biosynthetic process GO:0071073
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids.
1 Q2PQK2 (/ISS)
Positive regulation of diacylglycerol biosynthetic process GO:1900482
Any process that activates or increases the frequency, rate or extent of diacylglycerol biosynthetic process.
1 Q2PQK2 (/ISS)
Negative regulation of protein acetylation GO:1901984
Any process that stops, prevents or reduces the frequency, rate or extent of protein acetylation.
1 Q2PQK2 (/ISS)
Positive regulation of lactation GO:1903489
Any process that activates or increases the frequency, rate or extent of lactation.
1 Q2PQK2 (/ISS)
Positive regulation of feeding behavior GO:2000253
Any process that activates or increases the frequency, rate or extent of feeding behavior.
1 Q2PQK2 (/ISS)
Positive regulation of steroid hormone secretion GO:2000833
Any process that activates or increases the frequency, rate or extent of steroid hormone secretion.
1 Q2PQK2 (/ISS)
Negative regulation of testosterone secretion GO:2000844
Any process that stops, prevents or reduces the frequency, rate or extent of testosterone secretion.
1 Q2PQK2 (/ISS)
Positive regulation of aldosterone secretion GO:2000860
Any process that activates or increases the frequency, rate or extent of aldosterone secretion.
1 Q2PQK2 (/ISS)

There are 16 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
75 A0A087RIM6 (/ISS) A0A093NDD2 (/ISS) A0FJ27 (/ISS) A1Z074 (/ISS) A1Z074 (/ISS) A1Z074 (/ISS) A1Z074 (/ISS) A1Z074 (/ISS) A1Z074 (/ISS) A4GX98 (/ISS)
(65 more)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
43 A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4GX95 (/IDA) A4LAP1 (/IDA) B0FPG4 (/IDA) B0FPG4 (/IDA) B0FPG6 (/IDA) B0FPG6 (/IDA)
(33 more)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
4 P01244 (/TAS) P01244 (/TAS) P06880 (/TAS) P06880 (/TAS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
4 P01244 (/IDA) P01244 (/IDA) P06880 (/IDA) P06880 (/IDA)
Secretory granule GO:0030141
A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules.
4 P01244 (/IDA) P01244 (/IDA) P06880 (/IDA) P06880 (/IDA)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
2 P06880 (/ISO) P06880 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 P06880 (/ISO) P06880 (/ISO)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 P01244 (/IDA) P01244 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 P06880 (/ISO) P06880 (/ISO)
Trans-Golgi network GO:0005802
The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination.
2 P06880 (/IDA) P06880 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 P01244 (/IDA) P01244 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 P06880 (/ISO) P06880 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 P06880 (/IDA) P06880 (/IDA)
Secretory granule GO:0030141
A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules.
2 P06880 (/ISO) P06880 (/ISO)
Collagen-containing extracellular matrix GO:0062023
An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells.
2 P01244 (/IDA) P01244 (/IDA)
Collagen-containing extracellular matrix GO:0062023
An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells.
2 P06880 (/ISO) P06880 (/ISO)
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