CATH Superfamily 1.20.1250.10
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 16: Fms-related tyrosine kinase 3 ligand
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Receptor tyrosine kinase binding GO:0030971
Interacting selectively and non-covalently with a receptor that possesses protein tyrosine kinase activity.
|
2 | P49772 (/IDA) P49772 (/IDA) |
Receptor tyrosine kinase binding GO:0030971
Interacting selectively and non-covalently with a receptor that possesses protein tyrosine kinase activity.
|
2 | P49772 (/IPI) P49772 (/IPI) |
Signaling receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
|
1 | P49771 (/TAS) |
There are 22 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
3 | P49771 (/IDA) P49772 (/IDA) P49772 (/IDA) |
Positive regulation of protein phosphorylation GO:0001934
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
|
2 | P49772 (/IGI) P49772 (/IGI) |
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
2 | P49772 (/ISO) P49772 (/ISO) |
Lymphocyte differentiation GO:0030098
The process in which a relatively unspecialized precursor cell acquires specialized features of a lymphocyte. A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin.
|
2 | P49772 (/IMP) P49772 (/IMP) |
Regulation of myeloid dendritic cell activation GO:0030885
Any process that modulates the frequency or rate of myeloid dendritic cell activation.
|
2 | P49772 (/IMP) P49772 (/IMP) |
Positive regulation of natural killer cell proliferation GO:0032819
Any process that activates or increases the frequency, rate or extent of natural killer cell proliferation.
|
2 | A0A0G2K6K8 (/IDA) A0A1W2Q6J3 (/IDA) |
Positive regulation of natural killer cell differentiation GO:0032825
Any process that activates or increases the frequency, rate or extent of natural killer cell differentiation.
|
2 | P49772 (/IMP) P49772 (/IMP) |
Embryonic hemopoiesis GO:0035162
The stages of blood cell formation that take place within the embryo.
|
2 | P49772 (/ISO) P49772 (/ISO) |
Positive regulation of myoblast differentiation GO:0045663
Any process that activates or increases the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
|
2 | P49772 (/IMP) P49772 (/IMP) |
Positive regulation of cell cycle GO:0045787
Any process that activates or increases the rate or extent of progression through the cell cycle.
|
2 | P49772 (/IDA) P49772 (/IDA) |
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
2 | P49772 (/IDA) P49772 (/IDA) |
Homeostasis of number of cells within a tissue GO:0048873
Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in a tissue.
|
2 | P49772 (/IDA) P49772 (/IDA) |
Homeostasis of number of cells within a tissue GO:0048873
Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in a tissue.
|
2 | P49772 (/IGI) P49772 (/IGI) |
Positive regulation of cell proliferation in bone marrow GO:0071864
A process that activates or increases the frequency, rate or extent of cell proliferation in the bone marrow.
|
2 | P49772 (/IGI) P49772 (/IGI) |
Negative regulation of apoptotic process in bone marrow cell GO:0071866
Any process that stops, prevents, or reduces the frequency, rate or extent of the occurrence or rate of cell death by apoptotic process in the bone marrow.
|
2 | P49772 (/IGI) P49772 (/IGI) |
Positive regulation of osteoclast proliferation GO:0090290
Any process that increases the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population.
|
2 | P49772 (/IDA) P49772 (/IDA) |
Positive regulation of osteoclast proliferation GO:0090290
Any process that increases the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population.
|
2 | P49772 (/IGI) P49772 (/IGI) |
Positive regulation of myoblast fusion GO:1901741
Any process that activates or increases the frequency, rate or extent of myoblast fusion.
|
2 | P49772 (/IMP) P49772 (/IMP) |
MAPK cascade GO:0000165
An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain an additional tiers: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell.
|
1 | P49771 (/TAS) |
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
|
1 | P49771 (/TAS) |
Cytokine-mediated signaling pathway GO:0019221
A series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
1 | P49771 (/TAS) |
Embryonic hemopoiesis GO:0035162
The stages of blood cell formation that take place within the embryo.
|
1 | P49771 (/IDA) |
There are 6 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
2 | P49772 (/IDA) P49772 (/IDA) |
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
2 | P49772 (/IDA) P49772 (/IDA) |
Intrinsic component of external side of plasma membrane GO:0031233
The component of a plasma membrane consisting of gene products and protein complexes that penetrate the external side of the plasma membrane only, either directly or via some covalently attached hydrophobic anchor.
|
2 | P49772 (/IDA) P49772 (/IDA) |
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
1 | P49771 (/TAS) |
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | P49771 (/NAS) |
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | P49771 (/NAS) |