The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Histidine kinase NarX, sensor domain
".
FunFam 1: Sensor protein
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Phosphorelay sensor kinase activity GO:0000155
Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response.
|
69 |
P0AFA2 (/IDA)
P0AFA2 (/IDA)
P0AFA2 (/IDA)
P0AFA2 (/IDA)
P0AFA2 (/IDA)
P0AFA2 (/IDA)
P0AFA2 (/IDA)
P0AFA2 (/IDA)
P0AFA2 (/IDA)
P0AFA2 (/IDA)
(59 more) |
|
Phosphoprotein phosphatase activity GO:0004721
Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kinases, these enzymes control the state of phosphorylation of cell proteins and thereby provide an important mechanism for regulating cellular activity.
|
69 |
P0AFA2 (/IDA)
P0AFA2 (/IDA)
P0AFA2 (/IDA)
P0AFA2 (/IDA)
P0AFA2 (/IDA)
P0AFA2 (/IDA)
P0AFA2 (/IDA)
P0AFA2 (/IDA)
P0AFA2 (/IDA)
P0AFA2 (/IDA)
(59 more) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
69 |
P0AFA2 (/IPI)
P0AFA2 (/IPI)
P0AFA2 (/IPI)
P0AFA2 (/IPI)
P0AFA2 (/IPI)
P0AFA2 (/IPI)
P0AFA2 (/IPI)
P0AFA2 (/IPI)
P0AFA2 (/IPI)
P0AFA2 (/IPI)
(59 more) |
There are 5 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
|
69 |
P0AFA2 (/IEP)
P0AFA2 (/IEP)
P0AFA2 (/IEP)
P0AFA2 (/IEP)
P0AFA2 (/IEP)
P0AFA2 (/IEP)
P0AFA2 (/IEP)
P0AFA2 (/IEP)
P0AFA2 (/IEP)
P0AFA2 (/IEP)
(59 more) |
|
Signal transduction by protein phosphorylation GO:0023014
A process in which the transfer of one or more phosphate groups to a substrate transmits a signal to the phosphorylated substrate.
|
69 |
P0AFA2 (/IDA)
P0AFA2 (/IDA)
P0AFA2 (/IDA)
P0AFA2 (/IDA)
P0AFA2 (/IDA)
P0AFA2 (/IDA)
P0AFA2 (/IDA)
P0AFA2 (/IDA)
P0AFA2 (/IDA)
P0AFA2 (/IDA)
(59 more) |
|
Protein autophosphorylation GO:0046777
The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation).
|
69 |
P0AFA2 (/IDA)
P0AFA2 (/IDA)
P0AFA2 (/IDA)
P0AFA2 (/IDA)
P0AFA2 (/IDA)
P0AFA2 (/IDA)
P0AFA2 (/IDA)
P0AFA2 (/IDA)
P0AFA2 (/IDA)
P0AFA2 (/IDA)
(59 more) |
|
Cellular response to nitrate GO:0071249
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrate stimulus.
|
69 |
P0AFA2 (/IEP)
P0AFA2 (/IEP)
P0AFA2 (/IEP)
P0AFA2 (/IEP)
P0AFA2 (/IEP)
P0AFA2 (/IEP)
P0AFA2 (/IEP)
P0AFA2 (/IEP)
P0AFA2 (/IEP)
P0AFA2 (/IEP)
(59 more) |
|
Cellular response to nitrite GO:0071250
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrite stimulus.
|
69 |
P0AFA2 (/IMP)
P0AFA2 (/IMP)
P0AFA2 (/IMP)
P0AFA2 (/IMP)
P0AFA2 (/IMP)
P0AFA2 (/IMP)
P0AFA2 (/IMP)
P0AFA2 (/IMP)
P0AFA2 (/IMP)
P0AFA2 (/IMP)
(59 more) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
69 |
P0AFA2 (/IDA)
P0AFA2 (/IDA)
P0AFA2 (/IDA)
P0AFA2 (/IDA)
P0AFA2 (/IDA)
P0AFA2 (/IDA)
P0AFA2 (/IDA)
P0AFA2 (/IDA)
P0AFA2 (/IDA)
P0AFA2 (/IDA)
(59 more) |
|
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
69 |
P0AFA2 (/RCA)
P0AFA2 (/RCA)
P0AFA2 (/RCA)
P0AFA2 (/RCA)
P0AFA2 (/RCA)
P0AFA2 (/RCA)
P0AFA2 (/RCA)
P0AFA2 (/RCA)
P0AFA2 (/RCA)
P0AFA2 (/RCA)
(59 more) |
