The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"ERV/ALR sulfhydryl oxidase domain
".
FunFam 3: Sulfhydryl oxidase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 12 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Flavin-linked sulfhydryl oxidase activity GO:0016971
Catalysis of the formation of disulfide bridges.
|
7 | A4QNU9 (/IDA) P27882 (/IDA) P27882 (/IDA) P27882 (/IDA) P27882 (/IDA) P27882 (/IDA) Q63042 (/IDA) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
6 | P27882 (/IPI) P27882 (/IPI) P27882 (/IPI) P27882 (/IPI) P27882 (/IPI) P55789 (/IPI) |
Thiol oxidase activity GO:0016972
Catalysis of the reaction: 4 R'C(R)SH + O2 = 2 R'C(R)S-S(R)CR' + 2 H2O.
|
5 | P27882 (/IMP) P27882 (/IMP) P27882 (/IMP) P27882 (/IMP) P27882 (/IMP) |
Protein disulfide oxidoreductase activity GO:0015035
Catalysis of the reaction: a protein with reduced sulfide groups = a protein with oxidized disulfide bonds.
|
2 | P56213 (/ISS) Q63042 (/ISS) |
Flavin-linked sulfhydryl oxidase activity GO:0016971
Catalysis of the formation of disulfide bridges.
|
2 | O14144 (/ISO) P56213 (/ISO) |
Flavin adenine dinucleotide binding GO:0050660
Interacting selectively and non-covalently with FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2.
|
2 | P56213 (/ISS) Q63042 (/ISS) |
Protein disulfide oxidoreductase activity GO:0015035
Catalysis of the reaction: a protein with reduced sulfide groups = a protein with oxidized disulfide bonds.
|
1 | P55789 (/IDA) |
Protein disulfide oxidoreductase activity GO:0015035
Catalysis of the reaction: a protein with reduced sulfide groups = a protein with oxidized disulfide bonds.
|
1 | P56213 (/ISO) |
Flavin-linked sulfhydryl oxidase activity GO:0016971
Catalysis of the formation of disulfide bridges.
|
1 | A4QNU9 (/IMP) |
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | A4QNU9 (/IDA) |
Flavin adenine dinucleotide binding GO:0050660
Interacting selectively and non-covalently with FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2.
|
1 | P55789 (/IDA) |
Flavin adenine dinucleotide binding GO:0050660
Interacting selectively and non-covalently with FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2.
|
1 | P56213 (/ISO) |
There are 21 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cellular iron ion homeostasis GO:0006879
Any process involved in the maintenance of an internal steady state of iron ions at the level of a cell.
|
5 | P27882 (/IDA) P27882 (/IDA) P27882 (/IDA) P27882 (/IDA) P27882 (/IDA) |
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
|
5 | P27882 (/IMP) P27882 (/IMP) P27882 (/IMP) P27882 (/IMP) P27882 (/IMP) |
Protein import into mitochondrial intermembrane space GO:0045041
The import of proteins into the space between the inner and outer mitochondrial membranes.
|
5 | P27882 (/IMP) P27882 (/IMP) P27882 (/IMP) P27882 (/IMP) P27882 (/IMP) |
Liver development GO:0001889
The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes.
|
1 | A4QNU9 (/IMP) |
Protein folding GO:0006457
The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
|
1 | O14144 (/ISO) |
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
|
1 | A4QNU9 (/IMP) |
Response to lipopolysaccharide GO:0032496
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
|
1 | Q63042 (/IEP) |
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
|
1 | Q63042 (/IMP) |
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
|
1 | P56213 (/ISO) |
Negative regulation of natural killer cell mediated cytotoxicity GO:0045953
Any process that stops, prevents, or reduces the rate of natural killer mediated cytotoxicity.
|
1 | Q63042 (/IDA) |
Negative regulation of natural killer cell mediated cytotoxicity GO:0045953
Any process that stops, prevents, or reduces the rate of natural killer mediated cytotoxicity.
|
1 | P56213 (/ISO) |
Cellular response to lipopolysaccharide GO:0071222
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
|
1 | Q63042 (/IEP) |
Cellular response to tumor necrosis factor GO:0071356
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus.
|
1 | Q63042 (/IEP) |
Cellular response to actinomycin D GO:0072717
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an actinomycin D stimulus.
|
1 | Q63042 (/IEP) |
Cellular response to toxic substance GO:0097237
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus.
|
1 | Q63042 (/IEP) |
Liver regeneration GO:0097421
The regrowth of lost or destroyed liver.
|
1 | Q63042 (/IMP) |
Liver regeneration GO:0097421
The regrowth of lost or destroyed liver.
|
1 | P56213 (/ISO) |
Negative regulation of oxidative stress-induced neuron death GO:1903204
Any process that stops, prevents or reduces the frequency, rate or extent of oxidative stress-induced neuron death.
|
1 | Q63042 (/IDA) |
Negative regulation of oxidative stress-induced neuron death GO:1903204
Any process that stops, prevents or reduces the frequency, rate or extent of oxidative stress-induced neuron death.
|
1 | P56213 (/ISO) |
Positive regulation of DNA biosynthetic process GO:2000573
Any process that activates or increases the frequency, rate or extent of DNA biosynthetic process.
|
1 | Q63042 (/IDA) |
Positive regulation of DNA biosynthetic process GO:2000573
Any process that activates or increases the frequency, rate or extent of DNA biosynthetic process.
|
1 | P56213 (/ISO) |
There are 12 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
6 | P27882 (/HDA) P27882 (/HDA) P27882 (/HDA) P27882 (/HDA) P27882 (/HDA) P56213 (/HDA) |
Mitochondrial intermembrane space GO:0005758
The region between the inner and outer lipid bilayers of the mitochondrial envelope.
|
5 | P27882 (/IDA) P27882 (/IDA) P27882 (/IDA) P27882 (/IDA) P27882 (/IDA) |
Mitochondrial intermembrane space GO:0005758
The region between the inner and outer lipid bilayers of the mitochondrial envelope.
|
5 | P27882 (/TAS) P27882 (/TAS) P27882 (/TAS) P27882 (/TAS) P27882 (/TAS) |
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
4 | A4QNU9 (/IDA) H3BQQ4 (/IDA) P55789 (/IDA) Q63042 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
3 | H3BQQ4 (/IDA) P55789 (/IDA) Q63042 (/IDA) |
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
1 | Q63042 (/IDA) |
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
1 | P56213 (/ISO) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | A4QNU9 (/IDA) |
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | P56213 (/ISO) |
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | G4N0Y7 (/ISS) |
Mitochondrial intermembrane space GO:0005758
The region between the inner and outer lipid bilayers of the mitochondrial envelope.
|
1 | O14144 (/ISO) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | P56213 (/ISO) |