The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Alpha-catenin/vinculin-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 15: Cas scaffold protein family member 4

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein tyrosine kinase binding GO:1990782
Interacting selectively and non-covalently with protein tyrosine kinase.
1 Q9NQ75 (/IPI)
Protein tyrosine kinase binding GO:1990782
Interacting selectively and non-covalently with protein tyrosine kinase.
1 Q08EC4 (/ISO)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of cell migration GO:0030335
Any process that activates or increases the frequency, rate or extent of cell migration.
2 A5GFW5 (/ISS) Q08EC4 (/ISS)
Positive regulation of protein tyrosine kinase activity GO:0061098
Any process that increases the rate, frequency, or extent of protein tyrosine kinase activity.
2 A5GFW5 (/ISS) Q08EC4 (/ISS)
Positive regulation of substrate adhesion-dependent cell spreading GO:1900026
Any process that activates or increases the frequency, rate or extent of substrate adhesion-dependent cell spreading.
2 A5GFW5 (/ISS) Q08EC4 (/ISS)
Positive regulation of cell migration GO:0030335
Any process that activates or increases the frequency, rate or extent of cell migration.
1 Q9NQ75 (/IMP)
Positive regulation of cell migration GO:0030335
Any process that activates or increases the frequency, rate or extent of cell migration.
1 Q08EC4 (/ISO)
Positive regulation of protein tyrosine kinase activity GO:0061098
Any process that increases the rate, frequency, or extent of protein tyrosine kinase activity.
1 Q9NQ75 (/IDA)
Positive regulation of protein tyrosine kinase activity GO:0061098
Any process that increases the rate, frequency, or extent of protein tyrosine kinase activity.
1 Q08EC4 (/ISO)
Positive regulation of substrate adhesion-dependent cell spreading GO:1900026
Any process that activates or increases the frequency, rate or extent of substrate adhesion-dependent cell spreading.
1 Q9NQ75 (/IMP)
Positive regulation of substrate adhesion-dependent cell spreading GO:1900026
Any process that activates or increases the frequency, rate or extent of substrate adhesion-dependent cell spreading.
1 Q08EC4 (/ISO)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
2 A5GFW5 (/ISS) Q08EC4 (/ISS)
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
1 Q9NQ75 (/IDA)
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
1 Q08EC4 (/ISO)
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