The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5: Phosphatidylethanolamine N-methyltransferase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 15 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Phosphatidyl-N-methylethanolamine N-methyltransferase activity GO:0000773
Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine = S-adenosyl-L-homocysteine + phosphatidyl-N-dimethylethanolamine.
10 P05375 (/IDA) P05375 (/IDA) P05375 (/IDA) P05375 (/IDA) P05375 (/IDA) P05375 (/IDA) P05375 (/IDA) P05375 (/IDA) P05375 (/IDA) P05375 (/IDA)
Phosphatidyl-N-methylethanolamine N-methyltransferase activity GO:0000773
Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine = S-adenosyl-L-homocysteine + phosphatidyl-N-dimethylethanolamine.
10 P05375 (/IGI) P05375 (/IGI) P05375 (/IGI) P05375 (/IGI) P05375 (/IGI) P05375 (/IGI) P05375 (/IGI) P05375 (/IGI) P05375 (/IGI) P05375 (/IGI)
Phosphatidyl-N-methylethanolamine N-methyltransferase activity GO:0000773
Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine = S-adenosyl-L-homocysteine + phosphatidyl-N-dimethylethanolamine.
10 P05375 (/IMP) P05375 (/IMP) P05375 (/IMP) P05375 (/IMP) P05375 (/IMP) P05375 (/IMP) P05375 (/IMP) P05375 (/IMP) P05375 (/IMP) P05375 (/IMP)
Phosphatidyl-N-dimethylethanolamine N-methyltransferase activity GO:0080101
Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidyl-N-dimethylethanolamine = S-adenosyl-L-homocysteine + phosphatidylcholine.
10 P05375 (/IDA) P05375 (/IDA) P05375 (/IDA) P05375 (/IDA) P05375 (/IDA) P05375 (/IDA) P05375 (/IDA) P05375 (/IDA) P05375 (/IDA) P05375 (/IDA)
Phosphatidyl-N-dimethylethanolamine N-methyltransferase activity GO:0080101
Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidyl-N-dimethylethanolamine = S-adenosyl-L-homocysteine + phosphatidylcholine.
10 P05375 (/IGI) P05375 (/IGI) P05375 (/IGI) P05375 (/IGI) P05375 (/IGI) P05375 (/IGI) P05375 (/IGI) P05375 (/IGI) P05375 (/IGI) P05375 (/IGI)
Phosphatidyl-N-dimethylethanolamine N-methyltransferase activity GO:0080101
Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidyl-N-dimethylethanolamine = S-adenosyl-L-homocysteine + phosphatidylcholine.
10 P05375 (/IMP) P05375 (/IMP) P05375 (/IMP) P05375 (/IMP) P05375 (/IMP) P05375 (/IMP) P05375 (/IMP) P05375 (/IMP) P05375 (/IMP) P05375 (/IMP)
Phosphatidylethanolamine N-methyltransferase activity GO:0004608
Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidylethanolamine = S-adenosyl-L-homocysteine + H(+) + phosphatidyl-N-methylethanolamine.
1 Q08388 (/IDA)
Phosphatidylethanolamine N-methyltransferase activity GO:0004608
Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidylethanolamine = S-adenosyl-L-homocysteine + H(+) + phosphatidyl-N-methylethanolamine.
1 Q61907 (/ISO)
Phosphatidylethanolamine N-methyltransferase activity GO:0004608
Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidylethanolamine = S-adenosyl-L-homocysteine + H(+) + phosphatidyl-N-methylethanolamine.
1 Q61907 (/ISS)
Phosphatidylethanolamine N-methyltransferase activity GO:0004608
Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidylethanolamine = S-adenosyl-L-homocysteine + H(+) + phosphatidyl-N-methylethanolamine.
1 Q9UBM1 (/TAS)
Phosphatidylethanolamine binding GO:0008429
Interacting selectively and non-covalently with phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine.
1 Q08388 (/IDA)
Phosphatidylethanolamine binding GO:0008429
Interacting selectively and non-covalently with phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine.
1 Q61907 (/ISO)
S-adenosylmethionine-dependent methyltransferase activity GO:0008757
Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.
1 Q08388 (/IDA)
S-adenosylmethionine-dependent methyltransferase activity GO:0008757
Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.
1 Q61907 (/IMP)
S-adenosylmethionine-dependent methyltransferase activity GO:0008757
Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.
1 Q61907 (/ISO)

There are 27 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Phosphatidylcholine biosynthetic process GO:0006656
The chemical reactions and pathways resulting in the formation of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.
11 P05375 (/IDA) P05375 (/IDA) P05375 (/IDA) P05375 (/IDA) P05375 (/IDA) P05375 (/IDA) P05375 (/IDA) P05375 (/IDA) P05375 (/IDA) P05375 (/IDA)
(1 more)
Phosphatidylcholine biosynthetic process GO:0006656
The chemical reactions and pathways resulting in the formation of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.
10 P05375 (/IGI) P05375 (/IGI) P05375 (/IGI) P05375 (/IGI) P05375 (/IGI) P05375 (/IGI) P05375 (/IGI) P05375 (/IGI) P05375 (/IGI) P05375 (/IGI)
Phosphatidylcholine biosynthetic process GO:0006656
The chemical reactions and pathways resulting in the formation of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.
10 P05375 (/IMP) P05375 (/IMP) P05375 (/IMP) P05375 (/IMP) P05375 (/IMP) P05375 (/IMP) P05375 (/IMP) P05375 (/IMP) P05375 (/IMP) P05375 (/IMP)
Positive regulation of cold-induced thermogenesis GO:0120162
Any process that activates or increases the frequency, rate or extent of cold-induced thermogenesis.
2 Q08388 (/ISS) Q9UBM1 (/ISS)
Blastocyst hatching GO:0001835
The hatching of the cellular blastocyst from the zona pellucida.
1 Q61907 (/IMP)
Glycerophospholipid metabolic process GO:0006650
The chemical reactions and pathways involving glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.
1 Q08388 (/IMP)
Glycerophospholipid metabolic process GO:0006650
The chemical reactions and pathways involving glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.
1 Q61907 (/ISO)
Phosphatidylcholine biosynthetic process GO:0006656
The chemical reactions and pathways resulting in the formation of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.
1 Q61907 (/ISO)
Phosphatidylcholine biosynthetic process GO:0006656
The chemical reactions and pathways resulting in the formation of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.
1 Q61907 (/ISS)
Phosphatidylcholine biosynthetic process GO:0006656
The chemical reactions and pathways resulting in the formation of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.
1 Q9UBM1 (/TAS)
Sphingomyelin biosynthetic process GO:0006686
The chemical reactions and pathways resulting in the formation of sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine.
1 Q61907 (/IMP)
Response to nutrient GO:0007584
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus.
1 Q08388 (/IEP)
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
1 Q08388 (/IMP)
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
1 Q61907 (/ISO)
Response to vitamin GO:0033273
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin stimulus.
1 Q08388 (/IDA)
Response to vitamin GO:0033273
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin stimulus.
1 Q61907 (/ISO)
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
1 Q08388 (/IDA)
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
1 Q61907 (/ISO)
Response to amino acid GO:0043200
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.
1 Q08388 (/IEP)
Response to ethanol GO:0045471
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.
1 Q08388 (/IEP)
S-adenosylhomocysteine metabolic process GO:0046498
The chemical reactions and pathways involving S-adenosylhomocysteine; the L-enantiomer is formed from S-adenosylmethionine and is a strong inhibitor of S-adenosylmethionine-mediated methylation reactions. It can be cleaved to form adenosine and homocysteine.
1 Q08388 (/IDA)
S-adenosylhomocysteine metabolic process GO:0046498
The chemical reactions and pathways involving S-adenosylhomocysteine; the L-enantiomer is formed from S-adenosylmethionine and is a strong inhibitor of S-adenosylmethionine-mediated methylation reactions. It can be cleaved to form adenosine and homocysteine.
1 Q61907 (/ISO)
S-adenosylmethionine metabolic process GO:0046500
The chemical reactions and pathways involving S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.
1 Q08388 (/IDA)
S-adenosylmethionine metabolic process GO:0046500
The chemical reactions and pathways involving S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.
1 Q61907 (/ISO)
Positive regulation of lipoprotein metabolic process GO:0050747
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.
1 Q08388 (/IMP)
Positive regulation of lipoprotein metabolic process GO:0050747
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.
1 Q61907 (/ISO)
Positive regulation of cold-induced thermogenesis GO:0120162
Any process that activates or increases the frequency, rate or extent of cold-induced thermogenesis.
1 Q61907 (/IMP)

There are 12 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
11 P05375 (/HDA) P05375 (/HDA) P05375 (/HDA) P05375 (/HDA) P05375 (/HDA) P05375 (/HDA) P05375 (/HDA) P05375 (/HDA) P05375 (/HDA) P05375 (/HDA)
(1 more)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
10 P05375 (/HDA) P05375 (/HDA) P05375 (/HDA) P05375 (/HDA) P05375 (/HDA) P05375 (/HDA) P05375 (/HDA) P05375 (/HDA) P05375 (/HDA) P05375 (/HDA)
Cell periphery GO:0071944
The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures.
10 P05375 (/HDA) P05375 (/HDA) P05375 (/HDA) P05375 (/HDA) P05375 (/HDA) P05375 (/HDA) P05375 (/HDA) P05375 (/HDA) P05375 (/HDA) P05375 (/HDA)
Mitochondrial envelope GO:0005740
The double lipid bilayer enclosing the mitochondrion and separating its contents from the cell cytoplasm; includes the intermembrane space.
1 Q61907 (/TAS)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
1 Q61907 (/IDA)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
1 Q9UBM1 (/TAS)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 Q08388 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 Q61907 (/ISO)
Brush border membrane GO:0031526
The portion of the plasma membrane surrounding the brush border.
1 Q08388 (/IDA)
Brush border membrane GO:0031526
The portion of the plasma membrane surrounding the brush border.
1 Q61907 (/ISO)
Sarcolemma GO:0042383
The outer membrane of a muscle cell, consisting of the plasma membrane, a covering basement membrane (about 100 nm thick and sometimes common to more than one fiber), and the associated loose network of collagen fibers.
1 Q08388 (/IDA)
Sarcolemma GO:0042383
The outer membrane of a muscle cell, consisting of the plasma membrane, a covering basement membrane (about 100 nm thick and sometimes common to more than one fiber), and the associated loose network of collagen fibers.
1 Q61907 (/ISO)