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CATH Superfamily 1.20.120.1630

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 12: Polyprenol reductase 1

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Polyprenol reductase. [EC: 1.3.1.94]
Ditrans,polycis-dolichol + NADP(+) = ditrans,polycis-polyprenol + NADPH.
  • The reaction occurs in the reverse direction with reduction of the terminal double bond next to the alcohol group.
  • Isolated from human fetal brain tissue but present in all eukaryotes.
  • In mammalian cells dolichols are predominantly 18-21 isoprene units in length.
 25 A0A0E0DHG7 A0A0E0DHG7 A0A0E0DHG7 A0A0E0DHG7 A0A0E0DHG7 A0A0E0H4R3 A0A0E0H4R3 A0A0E0H4R3 A0A0E0H4R3 A0A0E0H4R3
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