The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"HPT domain
".
FunFam 2: Histidine kinase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Phosphorelay sensor kinase activity GO:0000155
Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response.
|
115 |
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
(105 more) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
115 |
P0AEC5 (/IPI)
P0AEC5 (/IPI)
P0AEC5 (/IPI)
P0AEC5 (/IPI)
P0AEC5 (/IPI)
P0AEC5 (/IPI)
P0AEC5 (/IPI)
P0AEC5 (/IPI)
P0AEC5 (/IPI)
P0AEC5 (/IPI)
(105 more) |
|
Histidine phosphotransfer kinase activity GO:0009927
Serves as a phospho-His intermediate enabling the transfer of phospho group between a hybrid kinase and a response regulator.
|
115 |
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
(105 more) |
There are 5 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Phosphorelay signal transduction system GO:0000160
A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins.
|
115 |
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
(105 more) |
|
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
|
115 |
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
(105 more) |
|
Response to hydrogen peroxide GO:0042542
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
|
115 |
P0AEC5 (/IMP)
P0AEC5 (/IMP)
P0AEC5 (/IMP)
P0AEC5 (/IMP)
P0AEC5 (/IMP)
P0AEC5 (/IMP)
P0AEC5 (/IMP)
P0AEC5 (/IMP)
P0AEC5 (/IMP)
P0AEC5 (/IMP)
(105 more) |
|
Protein autophosphorylation GO:0046777
The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation).
|
115 |
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
(105 more) |
|
Cellular response to organic substance GO:0071310
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.
|
115 |
P0AEC5 (/IEP)
P0AEC5 (/IEP)
P0AEC5 (/IEP)
P0AEC5 (/IEP)
P0AEC5 (/IEP)
P0AEC5 (/IEP)
P0AEC5 (/IEP)
P0AEC5 (/IEP)
P0AEC5 (/IEP)
P0AEC5 (/IEP)
(105 more) |
There are 1 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
115 |
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
P0AEC5 (/IDA)
(105 more) |
