CATH Superfamily 1.20.1160.20
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 6: Regulator of telomere elongation helicase 1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 10 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
DNA helicase activity GO:0003678
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of the DNA helix.
|
6 | A4K436 (/ISS) Q0VGM9 (/ISS) Q5RE34 (/ISS) Q5RJZ1 (/ISS) Q6H1L8 (/ISS) Q9NZ71 (/ISS) |
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
5 | A4K436 (/ISS) Q0VGM9 (/ISS) Q5RE34 (/ISS) Q5RJZ1 (/ISS) Q6H1L8 (/ISS) |
DNA helicase activity GO:0003678
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of the DNA helix.
|
2 | Q0VGM9 (/ISO) Q6H1L8 (/ISO) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | Q0VGM9 (/IPI) Q9NZ71 (/IPI) |
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
2 | Q0VGM9 (/ISO) Q6H1L8 (/ISO) |
DNA helicase activity GO:0003678
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of the DNA helix.
|
1 | Q0VGM9 (/IDA) |
DNA helicase activity GO:0003678
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of the DNA helix.
|
1 | Q9NZ71 (/IMP) |
Helicase activity GO:0004386
Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix.
|
1 | Q0VGM9 (/TAS) |
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
1 | Q9NZ71 (/IMP) |
DNA polymerase binding GO:0070182
Interacting selectively and non-covalently with a DNA polymerase.
|
1 | Q0VGM9 (/IPI) |
There are 38 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Telomere maintenance GO:0000723
Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins, the length of telomeric DNA and the replication and repair of the DNA. These processes includes those that shorten, lengthen, replicate and repair the telomeric DNA sequences.
|
5 | A4K436 (/ISS) Q5RE34 (/ISS) Q5RJZ1 (/ISS) Q6H1L8 (/ISS) Q9NZ71 (/ISS) |
Regulation of double-strand break repair via homologous recombination GO:0010569
Any process that modulates the frequency, rate or extent of the error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences.
|
5 | A4K436 (/ISS) Q0VGM9 (/ISS) Q5RE34 (/ISS) Q5RJZ1 (/ISS) Q6H1L8 (/ISS) |
Telomere maintenance GO:0000723
Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins, the length of telomeric DNA and the replication and repair of the DNA. These processes includes those that shorten, lengthen, replicate and repair the telomeric DNA sequences.
|
3 | Q0VGM9 (/IMP) Q6H1L8 (/IMP) Q9NZ71 (/IMP) |
Telomere maintenance GO:0000723
Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins, the length of telomeric DNA and the replication and repair of the DNA. These processes includes those that shorten, lengthen, replicate and repair the telomeric DNA sequences.
|
2 | Q0VGM9 (/ISO) Q6H1L8 (/ISO) |
Regulation of double-strand break repair via homologous recombination GO:0010569
Any process that modulates the frequency, rate or extent of the error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences.
|
2 | Q0VGM9 (/ISO) Q6H1L8 (/ISO) |
Telomeric loop disassembly GO:0090657
The telomere maintenance process in which telomeric loops are disassembled to permit efficient telomere replication.
|
2 | Q0VGM9 (/IMP) Q9NZ71 (/IMP) |
Telomeric loop disassembly GO:0090657
The telomere maintenance process in which telomeric loops are disassembled to permit efficient telomere replication.
|
2 | Q0VGM9 (/ISO) Q6H1L8 (/ISO) |
Positive regulation of telomere capping GO:1904355
Any process that activates or increases the frequency, rate or extent of telomere capping.
|
2 | Q0VGM9 (/ISO) Q6H1L8 (/ISO) |
Positive regulation of telomere maintenance via telomere lengthening GO:1904358
Any process that activates or increases the frequency, rate or extent of telomere maintenance via telomere lengthening.
|
2 | Q0VGM9 (/ISO) Q6H1L8 (/ISO) |
Negative regulation of t-circle formation GO:1904430
Any process that stops, prevents or reduces the frequency, rate or extent of t-circle formation.
|
2 | Q0VGM9 (/IMP) Q9NZ71 (/IMP) |
Negative regulation of t-circle formation GO:1904430
Any process that stops, prevents or reduces the frequency, rate or extent of t-circle formation.
|
2 | Q0VGM9 (/ISO) Q6H1L8 (/ISO) |
Strand displacement GO:0000732
The rejection of the broken 3' single-strand DNA molecule that formed heteroduplex DNA with its complement in an intact duplex DNA. The Watson-Crick base pairing in the original duplex is restored. The rejected 3' single-strand DNA molecule reanneals with its original complement to reform two intact duplex molecules.
|
1 | Q0VGM9 (/IDA) |
Strand displacement GO:0000732
The rejection of the broken 3' single-strand DNA molecule that formed heteroduplex DNA with its complement in an intact duplex DNA. The Watson-Crick base pairing in the original duplex is restored. The rejected 3' single-strand DNA molecule reanneals with its original complement to reform two intact duplex molecules.
|
1 | Q9NZ71 (/ISS) |
Strand displacement GO:0000732
The rejection of the broken 3' single-strand DNA molecule that formed heteroduplex DNA with its complement in an intact duplex DNA. The Watson-Crick base pairing in the original duplex is restored. The rejected 3' single-strand DNA molecule reanneals with its original complement to reform two intact duplex molecules.
|
1 | Q9NZ71 (/TAS) |
Regulation of double-strand break repair via homologous recombination GO:0010569
Any process that modulates the frequency, rate or extent of the error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences.
|
1 | Q9NZ71 (/IMP) |
Replication fork processing GO:0031297
The process in which a DNA replication fork that has stalled is restored to a functional state and replication is restarted. The stalling may be due to DNA damage, DNA secondary structure, bound proteins, dNTP shortage, or other causes.
|
1 | Q0VGM9 (/IDA) |
Replication fork processing GO:0031297
The process in which a DNA replication fork that has stalled is restored to a functional state and replication is restarted. The stalling may be due to DNA damage, DNA secondary structure, bound proteins, dNTP shortage, or other causes.
|
1 | Q9NZ71 (/ISS) |
Positive regulation of telomere maintenance GO:0032206
Any process that activates or increases the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA.
|
1 | Q0VGM9 (/IMP) |
Positive regulation of telomere maintenance GO:0032206
Any process that activates or increases the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA.
|
1 | Q9NZ71 (/ISS) |
DNA duplex unwinding GO:0032508
The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating a region of unpaired single strands.
|
1 | Q0VGM9 (/IDA) |
DNA duplex unwinding GO:0032508
The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating a region of unpaired single strands.
|
1 | Q9NZ71 (/ISS) |
Telomere maintenance in response to DNA damage GO:0043247
Any process that occur in response to the presence of critically short or damaged telomeres.
|
1 | Q0VGM9 (/IMP) |
Telomere maintenance in response to DNA damage GO:0043247
Any process that occur in response to the presence of critically short or damaged telomeres.
|
1 | Q9NZ71 (/ISS) |
Negative regulation of DNA recombination GO:0045910
Any process that stops, prevents, or reduces the frequency, rate or extent of DNA recombination.
|
1 | Q0VGM9 (/IDA) |
Negative regulation of DNA recombination GO:0045910
Any process that stops, prevents, or reduces the frequency, rate or extent of DNA recombination.
|
1 | Q9NZ71 (/ISS) |
Telomeric D-loop disassembly GO:0061820
A telomere loop disassembly process that results in the disassembly of telomeric D-loops. A telomeric D-loop is a three-stranded DNA displacement loop that forms at the site where the telomeric 3' single-stranded DNA overhang (formed of the repeat sequence TTAGGG in mammals) is tucked back inside the double-stranded component of telomeric DNA molecule, thus forming a t-loop or telomeric-loop and protecting the chromosome terminus.
|
1 | Q0VGM9 (/TAS) |
Telomeric loop disassembly GO:0090657
The telomere maintenance process in which telomeric loops are disassembled to permit efficient telomere replication.
|
1 | Q0VGM9 (/IDA) |
Telomeric loop disassembly GO:0090657
The telomere maintenance process in which telomeric loops are disassembled to permit efficient telomere replication.
|
1 | Q9NZ71 (/ISS) |
Mitotic telomere maintenance via semi-conservative replication GO:1902990
Any telomere maintenance via semi-conservative replication that is involved in mitotic cell cycle.
|
1 | Q0VGM9 (/IDA) |
Mitotic telomere maintenance via semi-conservative replication GO:1902990
Any telomere maintenance via semi-conservative replication that is involved in mitotic cell cycle.
|
1 | Q9NZ71 (/ISS) |
Positive regulation of telomere capping GO:1904355
Any process that activates or increases the frequency, rate or extent of telomere capping.
|
1 | Q9NZ71 (/IMP) |
Positive regulation of telomere maintenance via telomere lengthening GO:1904358
Any process that activates or increases the frequency, rate or extent of telomere maintenance via telomere lengthening.
|
1 | Q9NZ71 (/IMP) |
Negative regulation of t-circle formation GO:1904430
Any process that stops, prevents or reduces the frequency, rate or extent of t-circle formation.
|
1 | Q9NZ71 (/ISS) |
Negative regulation of t-circle formation GO:1904430
Any process that stops, prevents or reduces the frequency, rate or extent of t-circle formation.
|
1 | Q9NZ71 (/TAS) |
Negative regulation of telomere maintenance in response to DNA damage GO:1904506
Any process that stops, prevents or reduces the frequency, rate or extent of telomere maintenance in response to DNA damage.
|
1 | Q0VGM9 (/IMP) |
Negative regulation of telomere maintenance in response to DNA damage GO:1904506
Any process that stops, prevents or reduces the frequency, rate or extent of telomere maintenance in response to DNA damage.
|
1 | Q9NZ71 (/ISS) |
Positive regulation of telomeric loop disassembly GO:1904535
Any process that activates or increases the frequency, rate or extent of telomeric loop disassembly.
|
1 | Q0VGM9 (/IDA) |
Positive regulation of telomeric loop disassembly GO:1904535
Any process that activates or increases the frequency, rate or extent of telomeric loop disassembly.
|
1 | Q9NZ71 (/ISS) |
There are 6 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
5 | A4K436 (/ISS) Q5RE34 (/ISS) Q5RJZ1 (/ISS) Q6H1L8 (/ISS) Q9NZ71 (/ISS) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
3 | Q0VGM9 (/IDA) Q6H1L8 (/IDA) Q9NZ71 (/IDA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
2 | Q0VGM9 (/ISO) Q6H1L8 (/ISO) |
Chromosome, telomeric region GO:0000781
The terminal region of a linear chromosome that includes the telomeric DNA repeats and associated proteins.
|
1 | Q0VGM9 (/IDA) |
Chromosome, telomeric region GO:0000781
The terminal region of a linear chromosome that includes the telomeric DNA repeats and associated proteins.
|
1 | Q9NZ71 (/ISS) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q9NZ71 (/TAS) |