The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Clostridium botulinum neurotoxin b, "coiled-coil" domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Botulinum neurotoxin type D

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Bontoxilysin. [EC: 3.4.24.69]
Limited hydrolysis of proteins of the neuroexocytosis apparatus, synaptobrevins, SNAP25 or syntaxin. No detected action on small molecule substrates.
  • Belongs to peptidase family M27.
10 P18640 P18640 P18640 P19321 Q332E0 Q332E0 Q332E0 Q93HT3 Q93HT3 Q93HT3
Tentoxilysin. [EC: 3.4.24.68]
Hydrolysis of 76-Gln-|-Phe-77 bond in synaptobrevin 2.
  • Belongs to peptidase family M27.
1 P04958