The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Rhodopsin 7-helix transmembrane proteins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 18: Rhodopsin

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 23 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
11-cis retinal binding GO:0005502
Interacting selectively and non-covalently with 11-cis retinal, an isomer of retinal that plays an important role in the visual process in most vertebrates. 11-cis retinal combines with opsin in the rods (scotopsin) to form rhodopsin or visual purple. Retinal is one of the three compounds that makes up vitamin A.
86 O18766 (/ISS) O42604 (/ISS) O62791 (/ISS) O62791 (/ISS) O62792 (/ISS) O62793 (/ISS) O62794 (/ISS) O62795 (/ISS) O62796 (/ISS) O62796 (/ISS)
(76 more)
G protein-coupled photoreceptor activity GO:0008020
Combining with incidental electromagnetic radiation, particularly visible light, and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
84 O18766 (/ISS) O42604 (/ISS) O62791 (/ISS) O62791 (/ISS) O62792 (/ISS) O62793 (/ISS) O62794 (/ISS) O62795 (/ISS) O62796 (/ISS) O62796 (/ISS)
(74 more)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
23 A0A087QJF2 (/ISS) A0A091ERU1 (/ISS) A0A091GD08 (/ISS) A0A091J4G9 (/ISS) A0A091LHT1 (/ISS) A0A091VGC1 (/ISS) A0A091VGC1 (/ISS) A0A093NHR6 (/ISS) A0A093Q1T7 (/ISS) A0A094KUZ7 (/ISS)
(13 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
9 P02699 (/IPI) P08100 (/IPI) P08100 (/IPI) P08100 (/IPI) P08100 (/IPI) P08100 (/IPI) P08100 (/IPI) P15409 (/IPI) P29403 (/IPI)
Photoreceptor activity GO:0009881
The function of absorbing and responding to incidental electromagnetic radiation, particularly visible light. The response may involve a change in conformation.
7 P35359 (/NAS) P35359 (/NAS) Q9W6A5 (/NAS) Q9W6A5 (/NAS) Q9W6A6 (/NAS) Q9W6A6 (/NAS) Q9W6A9 (/NAS)
G protein-coupled receptor activity GO:0004930
Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
6 P08100 (/TAS) P08100 (/TAS) P08100 (/TAS) P08100 (/TAS) P08100 (/TAS) P08100 (/TAS)
Retinal binding GO:0016918
Interacting selectively and non-covalently with retinal, one of the forms of vitamin A. Retinal plays an important role in the visual process in most vertebrates, combining with opsins to form visual pigments in the retina.
5 A4FUN8 (/IDA) P35359 (/IDA) P35359 (/IDA) P51489 (/IDA) Q9PTX9 (/IDA)
Signaling receptor activity GO:0038023
Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.
5 P03999 (/TAS) P03999 (/TAS) P03999 (/TAS) P03999 (/TAS) P03999 (/TAS)
G-protein alpha-subunit binding GO:0001965
Interacting selectively and non-covalently with a G-protein alpha subunit. The alpha subunit binds a guanine nucleotide.
4 F1P3Y2 (/IPI) F1P3Y2 (/IPI) P02699 (/IPI) P22328 (/IPI)
G protein-coupled photoreceptor activity GO:0008020
Combining with incidental electromagnetic radiation, particularly visible light, and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
4 P02699 (/IDA) P35359 (/IDA) P35359 (/IDA) Q9PTX9 (/IDA)
Photoreceptor activity GO:0009881
The function of absorbing and responding to incidental electromagnetic radiation, particularly visible light. The response may involve a change in conformation.
4 A4FUN8 (/IDA) P35359 (/IDA) P35359 (/IDA) Q9PTX9 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
3 F1P3Y2 (/IDA) F1P3Y2 (/IDA) P22328 (/IDA)
Blue light photoreceptor activity GO:0009882
The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 400-470nm. The response may involve a change in conformation.
2 Q9W6A8 (/NAS) Q9W6A8 (/NAS)
Retinal binding GO:0016918
Interacting selectively and non-covalently with retinal, one of the forms of vitamin A. Retinal plays an important role in the visual process in most vertebrates, combining with opsins to form visual pigments in the retina.
2 P35359 (/NAS) P35359 (/NAS)
Opsin binding GO:0002046
Interacting selectively and non-covalently with an opsin, any of a group of hydrophobic, integral membrane glycoproteins located primarily in the disc membrane of rods or cones, involved in photoreception.
1 P02699 (/IDA)
Guanyl-nucleotide exchange factor activity GO:0005085
Stimulates the exchange of guanyl nucleotides associated with a GTPase. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
1 P02699 (/IDA)
11-cis retinal binding GO:0005502
Interacting selectively and non-covalently with 11-cis retinal, an isomer of retinal that plays an important role in the visual process in most vertebrates. 11-cis retinal combines with opsin in the rods (scotopsin) to form rhodopsin or visual purple. Retinal is one of the three compounds that makes up vitamin A.
1 P02699 (/IDA)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
1 P02699 (/IDA)
Retinal binding GO:0016918
Interacting selectively and non-covalently with retinal, one of the forms of vitamin A. Retinal plays an important role in the visual process in most vertebrates, combining with opsins to form visual pigments in the retina.
1 P15409 (/ISO)
Spectrin binding GO:0030507
Interacting selectively and non-covalently with spectrin, a protein that is the major constituent of the erythrocyte cytoskeletal network. It associates with band 4.1 (see band protein) and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. It is composed of nonhomologous chains, alpha and beta, which aggregate side-to-side in an antiparallel fashion to form dimers, tetramers, and higher polymers.
1 P51489 (/IDA)
Spectrin binding GO:0030507
Interacting selectively and non-covalently with spectrin, a protein that is the major constituent of the erythrocyte cytoskeletal network. It associates with band 4.1 (see band protein) and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. It is composed of nonhomologous chains, alpha and beta, which aggregate side-to-side in an antiparallel fashion to form dimers, tetramers, and higher polymers.
1 P15409 (/ISO)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 P02699 (/IPI)
Arrestin family protein binding GO:1990763
Interacting selectively and non-covalently with any member of the arrestin family, proteins involved in agonist-mediated desensitization of G protein-coupled receptors.
1 P02699 (/IPI)

There are 39 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Absorption of visible light GO:0016038
The reception of a (visible light) photon by a cell, visible light being defined as having a wavelength within the range 380-780 nm.
413 A0A076V826 (/ISS) A0A087QPU4 (/ISS) A0A091EAB5 (/ISS) A0A091GJZ2 (/ISS) A0A091GTK5 (/ISS) A0A091ICW2 (/ISS) A0A091JV71 (/ISS) A0A091LD46 (/ISS) A0A091LQ61 (/ISS) A0A091P9Q6 (/ISS)
(403 more)
Rhodopsin mediated signaling pathway GO:0016056
The series of molecular signals generated as a consequence of excitation of rhodopsin by a photon and the events that convert the absorbed photons into a cellular response.
85 O18766 (/ISS) O42604 (/ISS) O62791 (/ISS) O62791 (/ISS) O62792 (/ISS) O62793 (/ISS) O62794 (/ISS) O62795 (/ISS) O62796 (/ISS) O62796 (/ISS)
(75 more)
Protein-chromophore linkage GO:0018298
The covalent or noncovalent attachment of a chromophore to a protein.
72 A0A087QJF2 (/ISS) A0A087QPU4 (/ISS) A0A091EAB5 (/ISS) A0A091ERU1 (/ISS) A0A091GD08 (/ISS) A0A091GJZ2 (/ISS) A0A091GTK5 (/ISS) A0A091ICW2 (/ISS) A0A091J4G9 (/ISS) A0A091JV71 (/ISS)
(62 more)
Light absorption GO:0016037
The reception of a photon by a cell.
70 A0A087QJF2 (/ISS) A0A087QPU4 (/ISS) A0A091EAB5 (/ISS) A0A091ERU1 (/ISS) A0A091GD08 (/ISS) A0A091GJZ2 (/ISS) A0A091GTK5 (/ISS) A0A091ICW2 (/ISS) A0A091J4G9 (/ISS) A0A091JV71 (/ISS)
(60 more)
Protein homotrimerization GO:0070207
The formation of a protein homotrimer, a macromolecular structure consisting of three noncovalently associated identical subunits.
23 A0A087QJF2 (/ISS) A0A091ERU1 (/ISS) A0A091GD08 (/ISS) A0A091J4G9 (/ISS) A0A091LHT1 (/ISS) A0A091VGC1 (/ISS) A0A091VGC1 (/ISS) A0A093NHR6 (/ISS) A0A093Q1T7 (/ISS) A0A094KUZ7 (/ISS)
(13 more)
Retinoid metabolic process GO:0001523
The chemical reactions and pathways involving retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity.
11 P03999 (/TAS) P03999 (/TAS) P03999 (/TAS) P03999 (/TAS) P03999 (/TAS) P08100 (/TAS) P08100 (/TAS) P08100 (/TAS) P08100 (/TAS) P08100 (/TAS)
(1 more)
G protein-coupled receptor signaling pathway GO:0007186
A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576).
11 P03999 (/TAS) P03999 (/TAS) P03999 (/TAS) P03999 (/TAS) P03999 (/TAS) P08100 (/TAS) P08100 (/TAS) P08100 (/TAS) P08100 (/TAS) P08100 (/TAS)
(1 more)
Absorption of visible light GO:0016038
The reception of a (visible light) photon by a cell, visible light being defined as having a wavelength within the range 380-780 nm.
10 L8I7L1 (/IDA) P02699 (/IDA) P28682 (/IDA) P28683 (/IDA) P28683 (/IDA) P28684 (/IDA) P35359 (/IDA) P35359 (/IDA) P51475 (/IDA) Q9PTX9 (/IDA)
G protein-coupled receptor signaling pathway GO:0007186
A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576).
8 O18766 (/ISS) Q28886 (/ISS) Q68J47 (/ISS) Q6W3E1 (/ISS) Q769E8 (/ISS) Q769E8 (/ISS) Q8HY69 (/ISS) Q95KU1 (/ISS)
G protein-coupled receptor signaling pathway GO:0007186
A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576).
6 P08100 (/IMP) P08100 (/IMP) P08100 (/IMP) P08100 (/IMP) P08100 (/IMP) P08100 (/IMP)
Phototransduction, visible light GO:0007603
The sequence of reactions within a cell required to convert absorbed photons from visible light into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm.
6 P08100 (/TAS) P08100 (/TAS) P08100 (/TAS) P08100 (/TAS) P08100 (/TAS) P08100 (/TAS)
Rhodopsin mediated signaling pathway GO:0016056
The series of molecular signals generated as a consequence of excitation of rhodopsin by a photon and the events that convert the absorbed photons into a cellular response.
6 P08100 (/TAS) P08100 (/TAS) P08100 (/TAS) P08100 (/TAS) P08100 (/TAS) P08100 (/TAS)
Protein-chromophore linkage GO:0018298
The covalent or noncovalent attachment of a chromophore to a protein.
6 F1P3Y2 (/IDA) F1P3Y2 (/IDA) P22328 (/IDA) P28683 (/IDA) P28683 (/IDA) P51475 (/IDA)
Regulation of rhodopsin mediated signaling pathway GO:0022400
Any process that modulates the frequency, rate or extent of rhodopsin-mediated signaling.
6 P08100 (/TAS) P08100 (/TAS) P08100 (/TAS) P08100 (/TAS) P08100 (/TAS) P08100 (/TAS)
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
5 P03999 (/TAS) P03999 (/TAS) P03999 (/TAS) P03999 (/TAS) P03999 (/TAS)
Visual perception GO:0007601
The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image.
5 Q9W6A5 (/NAS) Q9W6A5 (/NAS) Q9W6A6 (/NAS) Q9W6A6 (/NAS) Q9W6A9 (/NAS)
Visual perception GO:0007601
The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image.
5 P03999 (/TAS) P03999 (/TAS) P03999 (/TAS) P03999 (/TAS) P03999 (/TAS)
Phototransduction GO:0007602
The sequence of reactions within a cell required to convert absorbed photons into a molecular signal.
5 P03999 (/TAS) P03999 (/TAS) P03999 (/TAS) P03999 (/TAS) P03999 (/TAS)
Light absorption GO:0016037
The reception of a photon by a cell.
5 F1P3Y2 (/IDA) F1P3Y2 (/IDA) P22328 (/IDA) P28683 (/IDA) P28683 (/IDA)
Protein homotrimerization GO:0070207
The formation of a protein homotrimer, a macromolecular structure consisting of three noncovalently associated identical subunits.
3 F1P3Y2 (/IDA) F1P3Y2 (/IDA) P22328 (/IDA)
Response to light stimulus GO:0009416
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.
2 P02699 (/IDA) Q9PTX9 (/IDA)
Detection of light stimulus GO:0009583
The series of events in which a light stimulus (in the form of photons) is received and converted into a molecular signal.
2 P35359 (/IDA) P35359 (/IDA)
Rhodopsin mediated signaling pathway GO:0016056
The series of molecular signals generated as a consequence of excitation of rhodopsin by a photon and the events that convert the absorbed photons into a cellular response.
2 P02699 (/IDA) P51489 (/IDA)
Rhodopsin mediated signaling pathway GO:0016056
The series of molecular signals generated as a consequence of excitation of rhodopsin by a photon and the events that convert the absorbed photons into a cellular response.
2 P35359 (/NAS) P35359 (/NAS)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
1 P15409 (/IDA)
G protein-coupled receptor signaling pathway GO:0007186
A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576).
1 P15409 (/ISO)
Visual perception GO:0007601
The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image.
1 P15409 (/IMP)
Phototransduction GO:0007602
The sequence of reactions within a cell required to convert absorbed photons into a molecular signal.
1 P15409 (/IMP)
Phototransduction, visible light GO:0007603
The sequence of reactions within a cell required to convert absorbed photons from visible light into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm.
1 P02699 (/IDA)
Response to light stimulus GO:0009416
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.
1 P15409 (/IMP)
Detection of light stimulus GO:0009583
The series of events in which a light stimulus (in the form of photons) is received and converted into a molecular signal.
1 P15409 (/IMP)
Red, far-red light phototransduction GO:0009585
The sequence of reactions within a cell required to convert absorbed photons from red or far-red light into a molecular signal; the red, far-red light range is defined as having a wavelength within the range 660-730 nm.
1 P51489 (/IDA)
Red, far-red light phototransduction GO:0009585
The sequence of reactions within a cell required to convert absorbed photons from red or far-red light into a molecular signal; the red, far-red light range is defined as having a wavelength within the range 660-730 nm.
1 P15409 (/ISO)
Rhodopsin mediated signaling pathway GO:0016056
The series of molecular signals generated as a consequence of excitation of rhodopsin by a photon and the events that convert the absorbed photons into a cellular response.
1 P15409 (/ISO)
Circadian regulation of gene expression GO:0032922
Any process that modulates the frequency, rate or extent of gene expression such that an expression pattern recurs with a regularity of approximately 24 hours.
1 Q9PTX9 (/IMP)
Photoreceptor cell maintenance GO:0045494
Any process preventing the degeneration of the photoreceptor, a specialized cell type that is sensitive to light.
1 P15409 (/IMP)
Sensory perception of light stimulus GO:0050953
The series of events required for an organism to receive a sensory light stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
1 P15409 (/IMP)
Retina development in camera-type eye GO:0060041
The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates.
1 P15409 (/IMP)
Cellular response to light stimulus GO:0071482
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.
1 P15409 (/IMP)

There are 45 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
86 O18766 (/ISS) O42604 (/ISS) O62791 (/ISS) O62791 (/ISS) O62792 (/ISS) O62793 (/ISS) O62794 (/ISS) O62795 (/ISS) O62796 (/ISS) O62796 (/ISS)
(76 more)
Photoreceptor disc membrane GO:0097381
Stack of disc membranes located inside a photoreceptor outer segment, and containing densely packed molecules of photoreceptor proteins that traverse the lipid bilayer. Disc membranes arise as evaginations of the ciliary membrane during the development of the outer segment and may or may not remain contiguous with the ciliary membrane.
81 O18766 (/ISS) O42604 (/ISS) O62791 (/ISS) O62791 (/ISS) O62792 (/ISS) O62793 (/ISS) O62794 (/ISS) O62795 (/ISS) O62796 (/ISS) O62796 (/ISS)
(71 more)
Cell GO:0005623
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
72 A0A087QJF2 (/ISS) A0A087QPU4 (/ISS) A0A091EAB5 (/ISS) A0A091ERU1 (/ISS) A0A091GD08 (/ISS) A0A091GJZ2 (/ISS) A0A091GTK5 (/ISS) A0A091ICW2 (/ISS) A0A091J4G9 (/ISS) A0A091JV71 (/ISS)
(62 more)
Photoreceptor outer segment membrane GO:0042622
The membrane surrounding the outer segment of a vertebrate photoreceptor.
24 O18766 (/ISS) O62791 (/ISS) O62791 (/ISS) O62792 (/ISS) O62793 (/ISS) O62794 (/ISS) O62795 (/ISS) O62796 (/ISS) O62796 (/ISS) O62798 (/ISS)
(14 more)
Photoreceptor inner segment membrane GO:0060342
The membrane surrounding the inner segment of a vertebrate photoreceptor. The photoreceptor inner segment contains mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs.
24 O18766 (/ISS) O62791 (/ISS) O62791 (/ISS) O62792 (/ISS) O62793 (/ISS) O62794 (/ISS) O62795 (/ISS) O62796 (/ISS) O62796 (/ISS) O62798 (/ISS)
(14 more)
Photoreceptor outer segment GO:0001750
The outer segment of a vertebrate photoreceptor that contains a stack of membrane discs embedded with photoreceptor proteins.
23 A0A087QJF2 (/ISS) A0A091ERU1 (/ISS) A0A091GD08 (/ISS) A0A091J4G9 (/ISS) A0A091LHT1 (/ISS) A0A091VGC1 (/ISS) A0A091VGC1 (/ISS) A0A093NHR6 (/ISS) A0A093Q1T7 (/ISS) A0A094KUZ7 (/ISS)
(13 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
23 O18766 (/ISS) O62791 (/ISS) O62791 (/ISS) O62792 (/ISS) O62793 (/ISS) O62794 (/ISS) O62795 (/ISS) O62796 (/ISS) O62796 (/ISS) O62798 (/ISS)
(13 more)
Photoreceptor outer segment GO:0001750
The outer segment of a vertebrate photoreceptor that contains a stack of membrane discs embedded with photoreceptor proteins.
19 F1P3Y2 (/IDA) F1P3Y2 (/IDA) P08100 (/IDA) P08100 (/IDA) P08100 (/IDA) P08100 (/IDA) P08100 (/IDA) P08100 (/IDA) P15409 (/IDA) P22328 (/IDA)
(9 more)
Photoreceptor disc membrane GO:0097381
Stack of disc membranes located inside a photoreceptor outer segment, and containing densely packed molecules of photoreceptor proteins that traverse the lipid bilayer. Disc membranes arise as evaginations of the ciliary membrane during the development of the outer segment and may or may not remain contiguous with the ciliary membrane.
12 P02699 (/TAS) P03999 (/TAS) P03999 (/TAS) P03999 (/TAS) P03999 (/TAS) P03999 (/TAS) P08100 (/TAS) P08100 (/TAS) P08100 (/TAS) P08100 (/TAS)
(2 more)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
11 P03999 (/TAS) P03999 (/TAS) P03999 (/TAS) P03999 (/TAS) P03999 (/TAS) P08100 (/TAS) P08100 (/TAS) P08100 (/TAS) P08100 (/TAS) P08100 (/TAS)
(1 more)
Photoreceptor outer segment membrane GO:0042622
The membrane surrounding the outer segment of a vertebrate photoreceptor.
8 P02699 (/IDA) P08100 (/IDA) P08100 (/IDA) P08100 (/IDA) P08100 (/IDA) P08100 (/IDA) P08100 (/IDA) P51489 (/IDA)
Golgi membrane GO:0000139
The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
7 P02699 (/TAS) P08100 (/TAS) P08100 (/TAS) P08100 (/TAS) P08100 (/TAS) P08100 (/TAS) P08100 (/TAS)
Photoreceptor inner segment GO:0001917
The inner segment of a vertebrate photoreceptor containing mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs.
7 P08100 (/IDA) P08100 (/IDA) P08100 (/IDA) P08100 (/IDA) P08100 (/IDA) P08100 (/IDA) P15409 (/IDA)
Cell GO:0005623
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
6 F1P3Y2 (/IDA) F1P3Y2 (/IDA) P22328 (/IDA) P28683 (/IDA) P28683 (/IDA) P51475 (/IDA)
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
6 P08100 (/IDA) P08100 (/IDA) P08100 (/IDA) P08100 (/IDA) P08100 (/IDA) P08100 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
6 P08100 (/IDA) P08100 (/IDA) P08100 (/IDA) P08100 (/IDA) P08100 (/IDA) P08100 (/IDA)
Golgi-associated vesicle membrane GO:0030660
The lipid bilayer surrounding a vesicle associated with the Golgi apparatus.
6 P08100 (/TAS) P08100 (/TAS) P08100 (/TAS) P08100 (/TAS) P08100 (/TAS) P08100 (/TAS)
Ciliary membrane GO:0060170
The portion of the plasma membrane surrounding a cilium.
6 P08100 (/TAS) P08100 (/TAS) P08100 (/TAS) P08100 (/TAS) P08100 (/TAS) P08100 (/TAS)
Photoreceptor inner segment membrane GO:0060342
The membrane surrounding the inner segment of a vertebrate photoreceptor. The photoreceptor inner segment contains mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs.
6 P08100 (/IDA) P08100 (/IDA) P08100 (/IDA) P08100 (/IDA) P08100 (/IDA) P08100 (/IDA)
Photoreceptor disc membrane GO:0097381
Stack of disc membranes located inside a photoreceptor outer segment, and containing densely packed molecules of photoreceptor proteins that traverse the lipid bilayer. Disc membranes arise as evaginations of the ciliary membrane during the development of the outer segment and may or may not remain contiguous with the ciliary membrane.
6 P08100 (/IDA) P08100 (/IDA) P08100 (/IDA) P08100 (/IDA) P08100 (/IDA) P08100 (/IDA)
Photoreceptor outer segment GO:0001750
The outer segment of a vertebrate photoreceptor that contains a stack of membrane discs embedded with photoreceptor proteins.
2 P15409 (/ISO) P51491 (/ISO)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
2 G1N5E0 (/ISS) G3UTJ4 (/ISS)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 P02699 (/IDA) P32310 (/IDA)
Ciliary basal body GO:0036064
A membrane-tethered, short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum) that is similar in structure to a centriole and derives from it. The cilium basal body is the site of assembly and remodelling of the cilium and serves as a nucleation site for axoneme growth. As well as anchoring the cilium, it is thought to provide a selective gateway regulating the entry of ciliary proteins and vesicles by intraflagellar transport.
2 G1N5E0 (/ISS) G3UTJ4 (/ISS)
Lamellar body GO:0042599
A membrane-bounded organelle, specialized for the storage and secretion of various substances (surfactant phospholipids, glycoproteins and acid phosphates) which are arranged in the form of tightly packed, concentric, membrane sheets or lamellae. Has some similar properties to, but is distinct from, a lysosome.
2 G1N5E0 (/ISS) G3UTJ4 (/ISS)
Photoreceptor inner segment GO:0001917
The inner segment of a vertebrate photoreceptor containing mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs.
1 P15409 (/ISO)
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
1 P15409 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 P15409 (/ISO)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 P02699 (/IDA)
Cell-cell junction GO:0005911
A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals.
1 P15409 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 P51475 (/IDA)
Outer membrane GO:0019867
The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites.
1 P02699 (/IDA)
Rough endoplasmic reticulum membrane GO:0030867
The lipid bilayer surrounding the rough endoplasmic reticulum.
1 P51489 (/IDA)
Rough endoplasmic reticulum membrane GO:0030867
The lipid bilayer surrounding the rough endoplasmic reticulum.
1 P15409 (/ISO)
Ciliary basal body GO:0036064
A membrane-tethered, short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum) that is similar in structure to a centriole and derives from it. The cilium basal body is the site of assembly and remodelling of the cilium and serves as a nucleation site for axoneme growth. As well as anchoring the cilium, it is thought to provide a selective gateway regulating the entry of ciliary proteins and vesicles by intraflagellar transport.
1 P51475 (/IDA)
Lamellar body GO:0042599
A membrane-bounded organelle, specialized for the storage and secretion of various substances (surfactant phospholipids, glycoproteins and acid phosphates) which are arranged in the form of tightly packed, concentric, membrane sheets or lamellae. Has some similar properties to, but is distinct from, a lysosome.
1 P51475 (/IDA)
Photoreceptor outer segment membrane GO:0042622
The membrane surrounding the outer segment of a vertebrate photoreceptor.
1 P15409 (/ISO)
Terminal bouton GO:0043195
Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it.
1 Q63652 (/IDA)
Terminal bouton GO:0043195
Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it.
1 P51491 (/ISO)
Cell body GO:0044297
The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections.
1 Q63652 (/IDA)
Cell body GO:0044297
The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections.
1 P51491 (/ISO)
Photoreceptor inner segment membrane GO:0060342
The membrane surrounding the inner segment of a vertebrate photoreceptor. The photoreceptor inner segment contains mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs.
1 P15409 (/ISO)
Lamellar body membrane GO:0097232
The lipid bilayer surrounding a lamellar body. A lamellar body is a membrane-bounded organelle, specialized for the storage and secretion of various substances (surfactant phospholipids, glycoproteins and acid phosphates) which are arranged in the form of tightly packed, concentric, membrane sheets or lamellae. Has some similar properties to, but is distinct from, a lysosome.
1 P51475 (/IDA)
Photoreceptor disc membrane GO:0097381
Stack of disc membranes located inside a photoreceptor outer segment, and containing densely packed molecules of photoreceptor proteins that traverse the lipid bilayer. Disc membranes arise as evaginations of the ciliary membrane during the development of the outer segment and may or may not remain contiguous with the ciliary membrane.
1 P15409 (/ISO)
G protein-coupled receptor complex GO:0097648
A protein complex that contains G protein-coupled receptors.
1 P02699 (/IDA)
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