The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Ribosomal RNA adenine dimethylase-like, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Ribosomal RNA small subunit methyltransferase A

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
RRNA (adenine-N6,N6-)-dimethyltransferase activity GO:0000179
Catalysis of the dimethylation two adjacent A residues in the loop closing the 3'-terminal stem of the 18S rRNA, using S-adenosyl-L-methionine as a methyl donor.
117 P06992 (/IDA) P06992 (/IDA) P06992 (/IDA) P06992 (/IDA) P06992 (/IDA) P06992 (/IDA) P06992 (/IDA) P06992 (/IDA) P06992 (/IDA) P06992 (/IDA)
(107 more)
Double-stranded DNA binding GO:0003690
Interacting selectively and non-covalently with double-stranded DNA.
117 P06992 (/IDA) P06992 (/IDA) P06992 (/IDA) P06992 (/IDA) P06992 (/IDA) P06992 (/IDA) P06992 (/IDA) P06992 (/IDA) P06992 (/IDA) P06992 (/IDA)
(107 more)
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
117 P06992 (/IDA) P06992 (/IDA) P06992 (/IDA) P06992 (/IDA) P06992 (/IDA) P06992 (/IDA) P06992 (/IDA) P06992 (/IDA) P06992 (/IDA) P06992 (/IDA)
(107 more)
RRNA binding GO:0019843
Interacting selectively and non-covalently with ribosomal RNA.
117 P06992 (/IDA) P06992 (/IDA) P06992 (/IDA) P06992 (/IDA) P06992 (/IDA) P06992 (/IDA) P06992 (/IDA) P06992 (/IDA) P06992 (/IDA) P06992 (/IDA)
(107 more)
RRNA (adenine-N6,N6-)-dimethyltransferase activity GO:0000179
Catalysis of the dimethylation two adjacent A residues in the loop closing the 3'-terminal stem of the 18S rRNA, using S-adenosyl-L-methionine as a methyl donor.
7 Q9KUS2 (/ISS) Q9KUS2 (/ISS) Q9KUS2 (/ISS) Q9KUS2 (/ISS) Q9KUS2 (/ISS) Q9KUS2 (/ISS) Q9KUS2 (/ISS)
RRNA methyltransferase activity GO:0008649
Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a nucleoside residue in an rRNA molecule.
1 Q54M56 (/IMP)
MRNA (2'-O-methyladenosine-N6-)-methyltransferase activity GO:0016422
Catalysis of the reaction: S-adenosyl-L-methionine + m(7)G(5')pppAm = S-adenosyl-L-homocysteine + m(7)G(5')pppm(6)Am.
1 O65090 (/ISS)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ribosomal small subunit assembly GO:0000028
The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the small ribosomal subunit.
117 P06992 (/IMP) P06992 (/IMP) P06992 (/IMP) P06992 (/IMP) P06992 (/IMP) P06992 (/IMP) P06992 (/IMP) P06992 (/IMP) P06992 (/IMP) P06992 (/IMP)
(107 more)
RRNA processing GO:0006364
Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.
117 P06992 (/IMP) P06992 (/IMP) P06992 (/IMP) P06992 (/IMP) P06992 (/IMP) P06992 (/IMP) P06992 (/IMP) P06992 (/IMP) P06992 (/IMP) P06992 (/IMP)
(107 more)
RRNA base methylation GO:0070475
The addition of a methyl group to an atom in the nucleoside base portion of a nucleotide residue in an rRNA molecule.
117 P06992 (/IMP) P06992 (/IMP) P06992 (/IMP) P06992 (/IMP) P06992 (/IMP) P06992 (/IMP) P06992 (/IMP) P06992 (/IMP) P06992 (/IMP) P06992 (/IMP)
(107 more)
RRNA modification GO:0000154
The covalent alteration of one or more nucleotides within an rRNA molecule to produce an rRNA molecule with a sequence that differs from that coded genetically.
7 Q9KUS2 (/ISS) Q9KUS2 (/ISS) Q9KUS2 (/ISS) Q9KUS2 (/ISS) Q9KUS2 (/ISS) Q9KUS2 (/ISS) Q9KUS2 (/ISS)
DNA-templated transcription, initiation GO:0006352
Any process involved in the assembly of the RNA polymerase preinitiation complex (PIC) at the core promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. The initiation phase ends just before and does not include promoter clearance, or release, which is the transition between the initiation and elongation phases of transcription.
1 Q54M56 (/IDA)
Response to cold GO:0009409
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
1 O65090 (/IMP)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
117 P06992 (/IDA) P06992 (/IDA) P06992 (/IDA) P06992 (/IDA) P06992 (/IDA) P06992 (/IDA) P06992 (/IDA) P06992 (/IDA) P06992 (/IDA) P06992 (/IDA)
(107 more)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q54M56 (/IDA)
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