The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"DNA helicase RuvA subunit, C-terminal domain
".
FunFam 74: Ubiquitin-associated domain-containing protein 2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
6 | Q8NBM4 (/IPI) Q8NBM4 (/IPI) Q8NBM4 (/IPI) Q8RXQ2 (/IPI) Q8RXQ2 (/IPI) Q9LET3 (/IPI) |
|
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
|
1 | O94685 (/ISM) |
|
Polyubiquitin modification-dependent protein binding GO:0031593
Interacting selectively and non-covalently with a protein upon poly-ubiquitination of the target protein.
|
1 | O94685 (/TAS) |
|
Ubiquitin binding GO:0043130
Interacting selectively and non-covalently with ubiquitin, a protein that when covalently bound to other cellular proteins marks them for proteolytic degradation.
|
1 | O94685 (/ISM) |
There are 10 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein localization to endoplasmic reticulum GO:0070972
A process in which a protein is transported to, or maintained in, a location within the endoplasmic reticulum.
|
3 | Q8NBM4 (/IDA) Q8NBM4 (/IDA) Q8NBM4 (/IDA) |
|
Negative regulation of retrograde protein transport, ER to cytosol GO:1904153
Any process that stops, prevents or reduces the frequency, rate or extent of retrograde protein transport, ER to cytosol.
|
3 | Q8NBM4 (/IMP) Q8NBM4 (/IMP) Q8NBM4 (/IMP) |
|
Heat acclimation GO:0010286
Any process that increases heat tolerance of an organism in response to high temperatures.
|
2 | Q8RXQ2 (/IGI) Q8RXQ2 (/IGI) |
|
Actin cortical patch assembly GO:0000147
Assembly of an actin cortical patch, a discrete actin-containing structure found at the plasma membrane of fungal cells.
|
1 | O94685 (/ISO) |
|
Intracellular protein transport GO:0006886
The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.
|
1 | O94685 (/IC) |
|
Endocytosis GO:0006897
A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
|
1 | O94685 (/ISS) |
|
Heat acclimation GO:0010286
Any process that increases heat tolerance of an organism in response to high temperatures.
|
1 | Q9LET3 (/IMP) |
|
Defense response to fungus GO:0050832
Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.
|
1 | Q9LET3 (/IGI) |
|
Protein localization to endoplasmic reticulum GO:0070972
A process in which a protein is transported to, or maintained in, a location within the endoplasmic reticulum.
|
1 | Q8R1K1 (/ISO) |
|
Negative regulation of retrograde protein transport, ER to cytosol GO:1904153
Any process that stops, prevents or reduces the frequency, rate or extent of retrograde protein transport, ER to cytosol.
|
1 | Q8R1K1 (/ISO) |
There are 5 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
6 | Q8NBM4 (/IDA) Q8NBM4 (/IDA) Q8NBM4 (/IDA) Q8RXQ2 (/IDA) Q8RXQ2 (/IDA) Q9LET3 (/IDA) |
|
Autophagosome GO:0005776
A double-membrane-bounded compartment that engulfs endogenous cellular material as well as invading microorganisms to target them to the lytic vacuole/lysosome for degradation as part of macroautophagy.
|
3 | Q8RXQ2 (/IDA) Q8RXQ2 (/IDA) Q9LET3 (/IDA) |
|
Phagophore GO:0061908
A disk-like structure that expands, rounds up into a cup-shaped structure, and eventually closes around its cargo (for example cytoplasmic components) to become an autophagosome or Cvt vesicle.
|
3 | Q8RXQ2 (/IDA) Q8RXQ2 (/IDA) Q9LET3 (/IDA) |
|
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
1 | Q8R1K1 (/ISO) |
|
Actin cortical patch GO:0030479
An endocytic patch that consists of an actin-containing structure found at the plasma membrane in cells; formed of networks of branched actin filaments that lie just beneath the plasma membrane and assemble, move, and disassemble rapidly. An example of this is the actin cortical patch found in Saccharomyces cerevisiae.
|
1 | O94685 (/ISO) |
