The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"DNA helicase RuvA subunit, C-terminal domain
".
FunFam 228: DNA (cytosine-5)-methyltransferase DRM2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
DNA (cytosine-5-)-methyltransferase activity GO:0003886
Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing cytosine = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.
|
1 | Q9LXE5 (/IMP) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q9M548 (/IPI) |
|
DNA-methyltransferase activity GO:0009008
Catalysis of the transfer of a methyl group to a DNA molecule.
|
1 | Q9M548 (/IMP) |
There are 5 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
DNA methylation GO:0006306
The covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine.
|
2 | Q9LXE5 (/IMP) Q9M548 (/IMP) |
|
Gene silencing GO:0016458
Any process carried out at the cellular level that results in either long-term transcriptional repression via action on chromatin structure or RNA mediated, post-transcriptional repression of gene expression.
|
2 | Q9LXE5 (/IMP) Q9M548 (/IMP) |
|
Defense response to fungus GO:0050832
Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.
|
2 | Q9LXE5 (/IGI) Q9M548 (/IGI) |
|
Histone H3-K9 methylation GO:0051567
The modification of histone H3 by addition of one or more methyl groups to lysine at position 9 of the histone.
|
2 | Q9LXE5 (/IGI) Q9M548 (/IGI) |
|
Methylation-dependent chromatin silencing GO:0006346
Repression of transcription by methylation of DNA, leading to the formation of heterochromatin.
|
1 | Q9LXE5 (/IMP) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q9M548 (/ISS) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q9M548 (/IDA) |
