The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Prion/Doppel protein, beta-ribbon domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4: Prion protein 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 0 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

There are 14 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156
The attachment of a plasma membrane adhesion molecule in one cell to an identical molecule in an adjacent cell.
8 A0A0B5JSC2 (/IDA) A8WGJ9 (/IDA) F1QX09 (/IDA) I6ZZC4 (/IDA) Q32PN3 (/IDA) Q3BDW0 (/IDA) Q50J87 (/IDA) Q5K0E1 (/IDA)
Central nervous system development GO:0007417
The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
7 A0A0B5JSC2 (/IGI) F1QX09 (/IGI) I6ZZC4 (/IGI) Q32PN3 (/IGI) Q3BDW0 (/IGI) Q50J87 (/IGI) Q5K0E1 (/IGI)
Calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules GO:0016338
The attachment of one cell to another cell via adhesion molecules that do not require the presence of calcium for the interaction.
7 A0A0B5JSC2 (/IMP) F1QX09 (/IMP) I6ZZC4 (/IMP) Q32PN3 (/IMP) Q3BDW0 (/IMP) Q50J87 (/IMP) Q5K0E1 (/IMP)
Adherens junction maintenance GO:0034334
The maintenance of an adherens junction. An adherens junction is a cell junction at which the cytoplasmic face of the plasma membrane is attached to actin filaments.
7 A0A0B5JSC2 (/IMP) F1QX09 (/IMP) I6ZZC4 (/IMP) Q32PN3 (/IMP) Q3BDW0 (/IMP) Q50J87 (/IMP) Q5K0E1 (/IMP)
Epiboly involved in gastrulation with mouth forming second GO:0055113
The expansion of one cell sheet over other cells involved in deuterostomic gastrulation.
7 A0A0B5JSC2 (/IGI) F1QX09 (/IGI) I6ZZC4 (/IGI) Q32PN3 (/IGI) Q3BDW0 (/IGI) Q50J87 (/IGI) Q5K0E1 (/IGI)
Epiboly involved in gastrulation with mouth forming second GO:0055113
The expansion of one cell sheet over other cells involved in deuterostomic gastrulation.
7 A0A0B5JSC2 (/IMP) F1QX09 (/IMP) I6ZZC4 (/IMP) Q32PN3 (/IMP) Q3BDW0 (/IMP) Q50J87 (/IMP) Q5K0E1 (/IMP)
Regulation of protein tyrosine kinase activity GO:0061097
Any process that modulates the rate, frequency, or extent of protein tyrosine kinase activity.
7 A0A0B5JSC2 (/IMP) F1QX09 (/IMP) I6ZZC4 (/IMP) Q32PN3 (/IMP) Q3BDW0 (/IMP) Q50J87 (/IMP) Q5K0E1 (/IMP)
Regulation of cell-cell adhesion mediated by cadherin GO:2000047
Any process that modulates the frequency, rate or extent of cell-cell adhesion mediated by cadherin.
7 A0A0B5JSC2 (/IMP) F1QX09 (/IMP) I6ZZC4 (/IMP) Q32PN3 (/IMP) Q3BDW0 (/IMP) Q50J87 (/IMP) Q5K0E1 (/IMP)
Homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156
The attachment of a plasma membrane adhesion molecule in one cell to an identical molecule in an adjacent cell.
1 Q50J87 (/IMP)
Trigeminal motor nucleus development GO:0021731
The process whose specific outcome is the progression of the trigeminal motor nucleus over time, from its formation to the mature structure.
1 A8WGJ9 (/IMP)
Regulation of apoptotic process GO:0042981
Any process that modulates the occurrence or rate of cell death by apoptotic process.
1 A8WGJ9 (/IMP)
Brain morphogenesis GO:0048854
The process in which the anatomical structures of the brain are generated and organized. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
1 A8WGJ9 (/IMP)
Posterior lateral line system development GO:0048915
The process whose specific outcome is the progression of the posterior lateral line system over time, from its formation to the mature structure. The posterior lateral line system develops from cranial ectodermal placodes, situated behind the ear, that give rise to both the neuromasts and the posterior lateral line sensory nerves that innervate the neuromasts. The posterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The neuromasts are innervated by several lateral line nerves, which project primarily to the hindbrain. The posterior mechanosensory lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance.
1 A8WGJ9 (/IMP)
Regulation of NMDA receptor activity GO:2000310
Any process that modulates the frequency, rate or extent of N-methyl-D-aspartate selective glutamate receptor activity.
1 A8WGJ9 (/IMP)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
8 A0A0B5JSC2 (/IDA) A8WGJ9 (/IDA) F1QX09 (/IDA) I6ZZC4 (/IDA) Q32PN3 (/IDA) Q3BDW0 (/IDA) Q50J87 (/IDA) Q5K0E1 (/IDA)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
7 A0A0B5JSC2 (/IDA) F1QX09 (/IDA) I6ZZC4 (/IDA) Q32PN3 (/IDA) Q3BDW0 (/IDA) Q50J87 (/IDA) Q5K0E1 (/IDA)
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