The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Prion/Doppel protein, beta-ribbon domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Prion-like protein doppel

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Copper ion binding GO:0005507
Interacting selectively and non-covalently with copper (Cu) ions.
8 Q9GJY2 (/ISS) Q9GJY2 (/ISS) Q9GJY2 (/ISS) Q9GK16 (/ISS) Q9GK16 (/ISS) Q9GK16 (/ISS) Q9GK16 (/ISS) Q9GK16 (/ISS)
Copper ion binding GO:0005507
Interacting selectively and non-covalently with copper (Cu) ions.
4 Q9QUG3 (/IDA) Q9QUG3 (/IDA) Q9QUG3 (/IDA) Q9UKY0 (/IDA)
Copper ion binding GO:0005507
Interacting selectively and non-covalently with copper (Cu) ions.
4 A0A075B668 (/ISO) Q9QUG3 (/ISO) Q9QUG3 (/ISO) Q9QUG3 (/ISO)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 Q9QUG3 (/IPI) Q9QUG3 (/IPI) Q9QUG3 (/IPI)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Acrosome reaction GO:0007340
The discharge, by sperm, of a single, anterior secretory granule following the sperm's attachment to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents into the zona pellucida.
9 Q9GJY2 (/ISS) Q9GJY2 (/ISS) Q9GJY2 (/ISS) Q9GK16 (/ISS) Q9GK16 (/ISS) Q9GK16 (/ISS) Q9GK16 (/ISS) Q9GK16 (/ISS) Q9UKY0 (/ISS)
Cellular copper ion homeostasis GO:0006878
Any process involved in the maintenance of an internal steady state of copper ions at the level of a cell.
3 Q9QUG3 (/IDA) Q9QUG3 (/IDA) Q9QUG3 (/IDA)
Single fertilization GO:0007338
The union of male and female gametes to form a zygote.
3 Q9QUG3 (/IMP) Q9QUG3 (/IMP) Q9QUG3 (/IMP)
Acrosome reaction GO:0007340
The discharge, by sperm, of a single, anterior secretory granule following the sperm's attachment to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents into the zona pellucida.
3 Q9QUG3 (/IMP) Q9QUG3 (/IMP) Q9QUG3 (/IMP)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Anchored component of external side of plasma membrane GO:0031362
The component of the plasma membrane consisting of the gene products that are tethered to the external side of the membrane only by a covalently attached anchor, such as a lipid group embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
9 Q9GJY2 (/ISS) Q9GJY2 (/ISS) Q9GJY2 (/ISS) Q9GK16 (/ISS) Q9GK16 (/ISS) Q9GK16 (/ISS) Q9GK16 (/ISS) Q9GK16 (/ISS) Q9UKY0 (/ISS)
Anchored component of external side of plasma membrane GO:0031362
The component of the plasma membrane consisting of the gene products that are tethered to the external side of the membrane only by a covalently attached anchor, such as a lipid group embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
4 Q9QUG3 (/IDA) Q9QUG3 (/IDA) Q9QUG3 (/IDA) Q9UKY0 (/IDA)
Anchored component of external side of plasma membrane GO:0031362
The component of the plasma membrane consisting of the gene products that are tethered to the external side of the membrane only by a covalently attached anchor, such as a lipid group embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
4 A0A075B668 (/ISO) Q9QUG3 (/ISO) Q9QUG3 (/ISO) Q9QUG3 (/ISO)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
1 Q9UKY0 (/TAS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q9UKY0 (/TAS)
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