The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Cytochrome c-like domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 55: PQQ-dependent dehydrogenase, methanol/ethanol fami...

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Alcohol dehydrogenase (azurin). [EC: 1.1.9.1]
A primary alcohol + azurin = an aldehyde + reduced azurin.
  • Occurs in Comamonas and Pseudomonas.
  • Does not require an amine activator.
  • Oxidizes a wide range of primary and secondary alcohols, and also aldehydes and large substrates such as sterols; methanol is not a substrate.
  • Usually assayed with phenazine methosulfate or ferricyanide.
  • Like all other quinoprotein alcohol dehydrogenases it has an 8-bladed 'propeller' structure, a calcium ion bound to the PQQ in the active site and an unusual disulfide ring structure in close proximity to the PQQ.
  • Formerly EC 1.1.98.1.
9 A0A1Y3KLH3 A0A1Y3KLH3 A0A1Y3KLH3 A0A2S6W5X4 A0A2S6W5X4 A0A2S6W5X4 Q8GR64 Q8GR64 Q8GR64
CATH-Gene3D is a Global Biodata Core Resource Learn more...