The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Cytochrome P450
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 62: Ent-kaurene oxidase 2

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Ent-kaurene monooxygenase. [EC: 1.14.14.86]
Ent-kaur-16-ene + 3 [reduced NADPH--hemoprotein reductase] + 3 O(2) = ent-kaur-16-en-19-oate + 3 [oxidized NADPH--hemoprotein reductase] + 4 H(2)O.
  • A cytochrome P450 (heme thiolate) protein found in plants.
  • Catalyzes three successive oxidations of the 4-methyl group of ent- kaurene giving kaurenoic acid.
  • Formerly EC 1.14.13.78.
5 A0A178UM76 A0A178UM76 Q5Z5R4 Q93ZB2 Q93ZB2
Syn-pimaradiene 3-monooxygenase. [EC: 1.14.14.68]
9-beta-pimara-7,15-diene + [reduced NADPH--hemoprotein reductase] + O(2) = 9-beta-pimara-7,15-diene-3-beta-ol + [oxidized NADPH--hemoprotein reductase] + H(2)O.
  • A cytochrome P450 (heme-thiolate) protein isolated from rice, Oryza sativa.
1 Q0DBF4
Ent-sandaracopimaradiene 3-hydroxylase. [EC: 1.14.14.70]
Ent-sandaracopimaradiene + [reduced NADPH--hemoprotein reductase] + O(2) = ent-sandaracopimaradien-3-beta-ol + [oxidized NADPH--hemoprotein reductase] + H(2)O.
  • A cytochrome P450 (heme-thiolate) protein isolated from Oryza sativa (rice).
  • Participates in the pathway for the biosynthesis of oryzalexins, a group of related phytoalexins produced by rice.
  • Can also use 9-beta-pimara-7,15-diene as substrate (cf. EC 1.14.14.68, syn-pimaradiene 3-monooxygenase).
  • Formerly EC 1.14.13.191.
1 Q0DBF4
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