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CATH Superfamily 1.10.630.10

Cytochrome P450

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Cytochrome P450
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 52: Ent-kaurenoic acid oxidase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Ent-kaurenoic acid monooxygenase. [EC: 1.14.14.107]
Ent-kaur-16-en-19-oate + 3 [reduced NADPH--hemoprotein reductase] + 3 O(2) = gibberellin A(12) + 3 [oxidized NADPH--hemoprotein reductase] + 4 H(2)O.
  • A cytochrome P450 (heme-thiolate) protein from plants.
  • Catalyzes three sucessive oxidations of ent-kaurenoic acid.
  • The second step includes a ring-B contraction giving the gibbane skeleton.
  • In pumpkin (Cucurbita maxima) ent-6-alpha,7-alpha-dihydroxykaur-16- en-19-oate is also formed.
  • Formerly EC 1.14.13.76.
 14 A0A384KBX4 A0A384KBX4 A0A384KBX4 O23051 O23051 Q058Q0 Q058Q0 Q058Q0 Q0WPQ3 Q0WPQ3
(4 more...)