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CATH Superfamily 1.10.630.10

Cytochrome P450

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Cytochrome P450
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 14: Abscisic acid 8

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
(+)-abscisic acid 8'-hydroxylase. [EC: 1.14.14.137]
(+)-abscisate + [reduced NADPH--hemoprotein reductase] + O(2) = 8'-hydroxyabscisate + [oxidized NADPH--hemoprotein reductase] + H(2)O.
  • A cytochrome P450 (heme-thiolate) protein found in plants.
  • Catalyzes the first step in the oxidative degradation of abscisic acid and is considered to be the pivotal enzyme in controlling the rate of degradation of this plant hormone.
  • CO inhibits the reaction, but its effects can be reversed by the presence of blue light.
  • The 8'-hydroxyabscisate formed can be converted into (-)-phaseic acid, most probably spontaneously.
  • Formerly EC 1.14.13.93.
 30 A0A0E0GN88 A0A0E0GN88 A0A0E0ID98 A0A0E0ID98 A0A0E0ID98 A0A178V0Q6 A0A178V0Q6 A0A178VA28 A0A178VA28 A2Z212
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