The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Cytochrome P450
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 120: Lanosterol 14-alpha demethylase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
10 P9WPP9 (/IPI) P9WPP9 (/IPI) P9WPP9 (/IPI) P9WPP9 (/IPI) P9WPP9 (/IPI) P9WPP9 (/IPI) P9WPP9 (/IPI) P9WPP9 (/IPI) P9WPP9 (/IPI) P9WPP9 (/IPI)
Sterol 14-demethylase activity GO:0008398
Catalysis of the reaction: obtusifoliol + 3 O2 + 3 NADPH + 3 H+ = 4-alpha-methyl-5-alpha-ergosta-8,14,24(28)-trien-3-beta-ol + formate + 3 NADP+ + 3 H2O.
10 P9WPP9 (/IDA) P9WPP9 (/IDA) P9WPP9 (/IDA) P9WPP9 (/IDA) P9WPP9 (/IDA) P9WPP9 (/IDA) P9WPP9 (/IDA) P9WPP9 (/IDA) P9WPP9 (/IDA) P9WPP9 (/IDA)
Heme binding GO:0020037
Interacting selectively and non-covalently with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.
10 P9WPP9 (/IDA) P9WPP9 (/IDA) P9WPP9 (/IDA) P9WPP9 (/IDA) P9WPP9 (/IDA) P9WPP9 (/IDA) P9WPP9 (/IDA) P9WPP9 (/IDA) P9WPP9 (/IDA) P9WPP9 (/IDA)

There are 1 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Sterol metabolic process GO:0016125
The chemical reactions and pathways involving sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
10 P9WPP9 (/IDA) P9WPP9 (/IDA) P9WPP9 (/IDA) P9WPP9 (/IDA) P9WPP9 (/IDA) P9WPP9 (/IDA) P9WPP9 (/IDA) P9WPP9 (/IDA) P9WPP9 (/IDA) P9WPP9 (/IDA)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
10 P9WPP9 (/IDA) P9WPP9 (/IDA) P9WPP9 (/IDA) P9WPP9 (/IDA) P9WPP9 (/IDA) P9WPP9 (/IDA) P9WPP9 (/IDA) P9WPP9 (/IDA) P9WPP9 (/IDA) P9WPP9 (/IDA)
CATH-Gene3D is a Global Biodata Core Resource Learn more...