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CATH Superfamily 1.10.630.10

Cytochrome P450

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Cytochrome P450
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 119: Alkane hydroxylase MAH1

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Long-chain fatty acid omega-monooxygenase. [EC: 1.14.14.80]
A long-chain fatty acid + [reduced NADPH--hemoprotein reductase] + O(2) = an omega-hydroxy-long-chain fatty acid + [oxidized NADPH--hemoprotein reductase] + H(2)O.
  • A cytochrome P450 (heme thiolate) enzyme.
  • The plant enzyme CYP704B1, which is involved in the synthesis of sporopollenin, a complex polymer found at the outer layer of spores and pollen, acts on palmitate (18:0), stearate (18:0) and oleate (18:1).
  • The plant enzyme CYP86A1 also acts on laurate (12:0).
  • The enzyme from the yeast Starmerella bombicola (CYP52M1) acts on C(16) to C(20) saturated and unsaturated fatty acids and can also hydroxylate the (omega-1) position.
  • The mammalian enzyme CYP4A acts on laurate (12:0), myristate (14:0), palmitate (16:0), oleate (18:1), and arachidonate (20:4).
  • Formerly EC 1.14.13.205.
 1 Q9C788