The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Cytochrome P450
".
FunFam 103: Steroid C26-monooxygenase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Steroid hydroxylase activity GO:0008395
Catalysis of the formation of a hydroxyl group on a steroid by incorporation of oxygen from O2.
|
7 | P9WPP1 (/IDA) P9WPP1 (/IDA) P9WPP1 (/IDA) P9WPP1 (/IDA) P9WPP1 (/IDA) P9WPP1 (/IDA) P9WPP1 (/IDA) |
|
Heme binding GO:0020037
Interacting selectively and non-covalently with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.
|
7 | P9WPP1 (/IDA) P9WPP1 (/IDA) P9WPP1 (/IDA) P9WPP1 (/IDA) P9WPP1 (/IDA) P9WPP1 (/IDA) P9WPP1 (/IDA) |
|
Cholest-4-en-3-one 26-monooxygenase activity GO:0036199
Catalysis of the reaction: cholest-4-en-3-one + NADH + H+ + O2 = 26-hydroxycholest-4-en-3-one + NAD+ + H2O. This reaction involves the hydroxylation of the C26 carbon, followed by oxidation of the alcohol to the carboxylic acid via the aldehyde intermediate.
|
7 | P9WPP1 (/IDA) P9WPP1 (/IDA) P9WPP1 (/IDA) P9WPP1 (/IDA) P9WPP1 (/IDA) P9WPP1 (/IDA) P9WPP1 (/IDA) |
There are 3 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cholesterol catabolic process GO:0006707
The chemical reactions and pathways resulting in the breakdown of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
|
14 |
P9WPP0 (/IMP)
P9WPP0 (/IMP)
P9WPP0 (/IMP)
P9WPP0 (/IMP)
P9WPP0 (/IMP)
P9WPP0 (/IMP)
P9WPP0 (/IMP)
P9WPP1 (/IMP)
P9WPP1 (/IMP)
P9WPP1 (/IMP)
(4 more) |
|
Cholesterol catabolic process GO:0006707
The chemical reactions and pathways resulting in the breakdown of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
|
7 | P9WPP1 (/IDA) P9WPP1 (/IDA) P9WPP1 (/IDA) P9WPP1 (/IDA) P9WPP1 (/IDA) P9WPP1 (/IDA) P9WPP1 (/IDA) |
|
Growth of symbiont in host GO:0044117
The increase in size or mass of an organism, occurring within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down host tissue. The host is defined as the larger of the organisms involved in a symbiotic interaction.
|
7 | P9WPP1 (/IMP) P9WPP1 (/IMP) P9WPP1 (/IMP) P9WPP1 (/IMP) P9WPP1 (/IMP) P9WPP1 (/IMP) P9WPP1 (/IMP) |
There are 0 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.