The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Cytochrome P450
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Cytochrome P450, family 2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 47 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Monooxygenase activity GO:0004497
Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.
12 P05181 (/TAS) P05182 (/TAS) P10610 (/TAS) P13107 (/TAS) P19225 (/TAS) P19225 (/TAS) P20812 (/TAS) P20814 (/TAS) P24903 (/TAS) P33260 (/TAS)
(2 more)
Monooxygenase activity GO:0004497
Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.
11 O35293 (/IDA) P05181 (/IDA) P08683 (/IDA) P10632 (/IDA) P11712 (/IDA) P11712 (/IDA) P20813 (/IDA) P24470 (/IDA) P33261 (/IDA) Q05421 (/IDA)
(1 more)
Monooxygenase activity GO:0004497
Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.
10 P12791 (/ISO) P33267 (/ISO) P56655 (/ISO) P56656 (/ISO) Q05421 (/ISO) Q148B1 (/ISO) Q5GLZ0 (/ISO) Q5GLZ1 (/ISO) Q64458 (/ISO) Q9CVC8 (/ISO)
Heme binding GO:0020037
Interacting selectively and non-covalently with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.
10 O18963 (/ISS) P05182 (/ISS) P08682 (/ISS) P33266 (/ISS) P51581 (/ISS) P51581 (/ISS) P79383 (/ISS) Q05421 (/ISS) Q6GUQ4 (/ISS) Q9MZY0 (/ISS)
Hsp70 protein binding GO:0030544
Interacting selectively and non-covalently with Hsp70 proteins, any of a group of heat shock proteins around 70kDa in size.
10 O18963 (/ISS) P05181 (/ISS) P08682 (/ISS) P33266 (/ISS) P51581 (/ISS) P51581 (/ISS) P79383 (/ISS) Q05421 (/ISS) Q6GUQ4 (/ISS) Q9MZY0 (/ISS)
Hsp90 protein binding GO:0051879
Interacting selectively and non-covalently with Hsp90 proteins, any of a group of heat shock proteins around 90kDa in size.
10 O18963 (/ISS) P05181 (/ISS) P08682 (/ISS) P33266 (/ISS) P51581 (/ISS) P51581 (/ISS) P79383 (/ISS) Q05421 (/ISS) Q6GUQ4 (/ISS) Q9MZY0 (/ISS)
Arachidonic acid epoxygenase activity GO:0008392
Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to a cis-epoxyeicosatrienoic acid.
8 P10632 (/IDA) P11712 (/IDA) P11712 (/IDA) P24470 (/IDA) P33272 (/IDA) Q6XVG2 (/IDA) Q91X77 (/IDA) Q9D816 (/IDA)
Arachidonic acid epoxygenase activity GO:0008392
Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to a cis-epoxyeicosatrienoic acid.
8 A0A1D5RLI1 (/ISO) E9Q5K4 (/ISO) O55071 (/ISO) Q3UEM4 (/ISO) Q6IEF7 (/ISO) Q8BWN7 (/ISO) Q8CIE7 (/ISO) Q8QZW4 (/ISO)
Steroid hydroxylase activity GO:0008395
Catalysis of the formation of a hydroxyl group on a steroid by incorporation of oxygen from O2.
7 B2RXZ2 (/ISO) P12791 (/ISO) P56593 (/ISO) Q148B1 (/ISO) Q5GLZ0 (/ISO) Q5GLZ1 (/ISO) Q9CVC8 (/ISO)
Caffeine oxidase activity GO:0034875
Catalysis of the reaction: caffeine + O2 + 2 H+ + 2 e- = 1,3,7-trimethyluric acid + H2O.
7 P56655 (/ISO) P56656 (/ISO) Q148B1 (/ISO) Q5GLZ0 (/ISO) Q5GLZ1 (/ISO) Q64458 (/ISO) Q9CVC8 (/ISO)
Oxidoreductase activity GO:0016491
Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
6 P04167 (/IDA) P05181 (/IDA) P11711 (/IDA) P11712 (/IDA) P11712 (/IDA) P33261 (/IDA)
Oxidoreductase activity GO:0016491
Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
6 P12791 (/ISO) Q05421 (/ISO) Q148B1 (/ISO) Q5GLZ0 (/ISO) Q5GLZ1 (/ISO) Q9CVC8 (/ISO)
Oxygen binding GO:0019825
Interacting selectively and non-covalently with oxygen (O2).
6 P05181 (/TAS) P20812 (/TAS) P20853 (/TAS) P24903 (/TAS) P33260 (/TAS) P33261 (/TAS)
Monooxygenase activity GO:0004497
Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.
5 P05178 (/NAS) P11712 (/NAS) P11712 (/NAS) P19225 (/NAS) P19225 (/NAS)
Heme binding GO:0020037
Interacting selectively and non-covalently with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.
5 P05181 (/IDA) P11509 (/IDA) P20813 (/IDA) P33261 (/IDA) Q16696 (/IDA)
Drug binding GO:0008144
Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
4 Q148B1 (/ISO) Q5GLZ0 (/ISO) Q5GLZ1 (/ISO) Q9CVC8 (/ISO)
Testosterone 16-alpha-hydroxylase activity GO:0008390
Catalysis of the reaction: testosterone + donor-H2 + O2 = 16-alpha-hydroxytestosterone + H2O.
4 Q148B1 (/ISO) Q5GLZ0 (/ISO) Q5GLZ1 (/ISO) Q9CVC8 (/ISO)
Steroid hydroxylase activity GO:0008395
Catalysis of the formation of a hydroxyl group on a steroid by incorporation of oxygen from O2.
4 P00176 (/IDA) P04167 (/IDA) P11711 (/IDA) P15149 (/IDA)
Heme binding GO:0020037
Interacting selectively and non-covalently with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.
4 P12791 (/ISO) P15392 (/ISO) P20852 (/ISO) Q05421 (/ISO)
Steroid hydroxylase activity GO:0008395
Catalysis of the formation of a hydroxyl group on a steroid by incorporation of oxygen from O2.
3 P11712 (/IMP) P11712 (/IMP) P33261 (/IMP)
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
3 P05181 (/IPI) P11509 (/IPI) P33261 (/IPI)
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
3 P15392 (/ISO) P20852 (/ISO) Q05421 (/ISO)
Caffeine oxidase activity GO:0034875
Catalysis of the reaction: caffeine + O2 + 2 H+ + 2 e- = 1,3,7-trimethyluric acid + H2O.
3 P10632 (/IDA) P11712 (/IDA) P11712 (/IDA)
Linoleic acid epoxygenase activity GO:0071614
Catalysis of an NADPH- and oxygen-dependent reaction that converts linoleic acid to a cis-epoxyoctadecenoic acid.
3 Q6XVG2 (/IDA) Q91X77 (/IDA) Q9D816 (/IDA)
Estrogen 16-alpha-hydroxylase activity GO:0101020
Catalysis of the reaction: estrogen + donor-H2 + O2 = 16-alpha-hydroxyestrogen + H2O.
3 P56655 (/ISO) P56656 (/ISO) Q64458 (/ISO)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 Q96SQ9 (/IPI) Q9WV19 (/IPI)
Drug binding GO:0008144
Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
2 P11712 (/IDA) P11712 (/IDA)
Coumarin 7-hydroxylase activity GO:0008389
Catalysis of the reaction: coumarin + O2 + NADPH + H+ = hydroxycoumarin + H2O + NADP+.
2 P15392 (/ISO) P20852 (/ISO)
Retinoic acid 4-hydroxylase activity GO:0008401
Catalysis of the conversion of retinoic acid to 4-hydroxy-retinoic acid.
2 P10632 (/IDA) P33260 (/IDA)
Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen GO:0016712
Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced flavin or flavoprotein and one other donor, and one atom of oxygen is incorporated into one donor.
2 P05182 (/IDA) P24903 (/IDA)
Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen GO:0016712
Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced flavin or flavoprotein and one other donor, and one atom of oxygen is incorporated into one donor.
2 P33267 (/ISO) Q05421 (/ISO)
Oxygen binding GO:0019825
Interacting selectively and non-covalently with oxygen (O2).
2 G3V9D2 (/NAS) Q9JJ02 (/NAS)
Hsp70 protein binding GO:0030544
Interacting selectively and non-covalently with Hsp70 proteins, any of a group of heat shock proteins around 70kDa in size.
2 P00176 (/IDA) P05182 (/IDA)
Hsp70 protein binding GO:0030544
Interacting selectively and non-covalently with Hsp70 proteins, any of a group of heat shock proteins around 70kDa in size.
2 P12791 (/ISO) Q05421 (/ISO)
Hsp90 protein binding GO:0051879
Interacting selectively and non-covalently with Hsp90 proteins, any of a group of heat shock proteins around 90kDa in size.
2 P00176 (/IDA) P05182 (/IDA)
Hsp90 protein binding GO:0051879
Interacting selectively and non-covalently with Hsp90 proteins, any of a group of heat shock proteins around 90kDa in size.
2 P12791 (/ISO) Q05421 (/ISO)
Thromboxane-A synthase activity GO:0004796
Catalysis of the reaction: prostaglandin H(2) = thromboxane A(2).
1 Q96SQ9 (/IDA)
Coumarin 7-hydroxylase activity GO:0008389
Catalysis of the reaction: coumarin + O2 + NADPH + H+ = hydroxycoumarin + H2O + NADP+.
1 P11509 (/IDA)
Testosterone 16-alpha-hydroxylase activity GO:0008390
Catalysis of the reaction: testosterone + donor-H2 + O2 = 16-alpha-hydroxytestosterone + H2O.
1 P08683 (/IMP)
Steroid hydroxylase activity GO:0008395
Catalysis of the formation of a hydroxyl group on a steroid by incorporation of oxygen from O2.
1 P15149 (/TAS)
Retinoic acid 4-hydroxylase activity GO:0008401
Catalysis of the conversion of retinoic acid to 4-hydroxy-retinoic acid.
1 Q96SQ9 (/TAS)
FMN binding GO:0010181
Interacting selectively and non-covalently with flavin mono nucleotide. Flavin mono nucleotide (FMN) is the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
1 P05182 (/IC)
Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen GO:0016709
Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor.
1 P05181 (/TAS)
Hydro-lyase activity GO:0016836
Catalysis of the cleavage of a carbon-oxygen bond by elimination of water.
1 Q96SQ9 (/IDA)
4-nitrophenol 2-monooxygenase activity GO:0018601
Catalysis of the reaction: 4-nitrophenol + H(+) + NADH + O(2) = 4-nitrocatechol + H(2)O + NAD(+).
1 P05181 (/IDA)
Oxygen binding GO:0019825
Interacting selectively and non-covalently with oxygen (O2).
1 Q8QFT4 (/IMP)
Estrogen 16-alpha-hydroxylase activity GO:0101020
Catalysis of the reaction: estrogen + donor-H2 + O2 = 16-alpha-hydroxyestrogen + H2O.
1 P10632 (/IDA)

There are 82 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Xenobiotic metabolic process GO:0006805
The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to living organisms. Used of chemical compounds, e.g. a xenobiotic chemical, such as a pesticide.
10 P05181 (/TAS) P08683 (/TAS) P10632 (/TAS) P11712 (/TAS) P11712 (/TAS) P20813 (/TAS) P24903 (/TAS) P33260 (/TAS) P33261 (/TAS) Q16696 (/TAS)
Drug metabolic process GO:0017144
The chemical reactions and pathways involving a drug, a substance used in the diagnosis, treatment or prevention of a disease; as used here antibiotic substances (see antibiotic metabolism) are considered to be drugs, even if not used in medical or veterinary practice.
9 P00176 (/IDA) P04167 (/IDA) P05181 (/IDA) P10632 (/IDA) P11509 (/IDA) P11712 (/IDA) P11712 (/IDA) P20813 (/IDA) P33261 (/IDA)
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
7 P05181 (/IDA) P05182 (/IDA) P10632 (/IDA) P11712 (/IDA) P11712 (/IDA) P20813 (/IDA) P33261 (/IDA)
Steroid metabolic process GO:0008202
The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.
6 P05181 (/IMP) P11509 (/IMP) P11712 (/IMP) P11712 (/IMP) P20813 (/IMP) P33261 (/IMP)
Exogenous drug catabolic process GO:0042738
The chemical reactions and pathways resulting in the breakdown of a drug that has originated externally to the cell or organism.
6 P10632 (/IDA) P11509 (/IDA) P11712 (/IDA) P11712 (/IDA) P20813 (/IDA) P33261 (/IDA)
Drug metabolic process GO:0017144
The chemical reactions and pathways involving a drug, a substance used in the diagnosis, treatment or prevention of a disease; as used here antibiotic substances (see antibiotic metabolism) are considered to be drugs, even if not used in medical or veterinary practice.
5 P05181 (/IMP) P11509 (/IMP) P11712 (/IMP) P11712 (/IMP) P20813 (/IMP)
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
5 P00176 (/IEP) P05178 (/IEP) P05179 (/IEP) P05182 (/IEP) P13107 (/IEP)
Icosanoid biosynthetic process GO:0046456
The chemical reactions and pathways resulting in the formation of icosanoids, any of a group of C20 polyunsaturated fatty acids.
5 P08683 (/IDA) P10632 (/IDA) P11712 (/IDA) P11712 (/IDA) P24470 (/IDA)
Response to organic cyclic compound GO:0014070
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
4 P00176 (/IEP) P04167 (/IEP) P05179 (/IEP) P13107 (/IEP)
Monoterpenoid metabolic process GO:0016098
The chemical reactions and pathways involving monoterpenoid compounds, terpenoids having a C10 skeleton.
4 P05181 (/IDA) P11712 (/IDA) P11712 (/IDA) P33261 (/IDA)
Epoxygenase P450 pathway GO:0019373
The chemical reactions and pathways by which arachidonic acid is converted to other compounds including epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids.
4 P10632 (/IDA) P11712 (/IDA) P11712 (/IDA) P33272 (/IDA)
Epoxygenase P450 pathway GO:0019373
The chemical reactions and pathways by which arachidonic acid is converted to other compounds including epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids.
4 P10632 (/TAS) P11712 (/TAS) P11712 (/TAS) P33261 (/TAS)
Long-chain fatty acid biosynthetic process GO:0042759
The chemical reactions and pathways resulting in the formation of long-chain fatty acids, any fatty acid with a chain length between C13 and C22.
4 P05181 (/TAS) P10632 (/TAS) P11712 (/TAS) P11712 (/TAS)
Omega-hydroxylase P450 pathway GO:0097267
The chemical reactions and pathways by which arachidonic acid is converted to other compounds initially by omega-hydroxylation.
4 P10632 (/TAS) P11712 (/TAS) P11712 (/TAS) P33261 (/TAS)
Lipid hydroxylation GO:0002933
The covalent attachment of a hydroxyl group to one or more fatty acids in a lipid.
3 P05181 (/IDA) P10632 (/IDA) Q92088 (/IDA)
Xenobiotic metabolic process GO:0006805
The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to living organisms. Used of chemical compounds, e.g. a xenobiotic chemical, such as a pesticide.
3 G3V9D2 (/NAS) P05182 (/NAS) Q9JJ02 (/NAS)
Estrogen metabolic process GO:0008210
The chemical reactions and pathways involving estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants.
3 P10632 (/IDA) P11712 (/IDA) P11712 (/IDA)
Arachidonic acid metabolic process GO:0019369
The chemical reactions and pathways involving arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer.
3 Q6XVG2 (/IDA) Q91X77 (/IDA) Q9D816 (/IDA)
Response to stilbenoid GO:0035634
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of exposure to a stilbenoid. Stilbenoids are secondary products of heartwood formation in trees that can act as phytoalexins. Stilbenoids are hydroxylated derivatives of stilbene. They belong to the family of phenylpropanoids and share most of their biosynthesis pathway with chalcones.
3 P12790 (/IEP) P15392 (/IEP) P20852 (/IEP)
Retinoic acid metabolic process GO:0042573
The chemical reactions and pathways involving retinoic acid, one of the three components that makes up vitamin A.
3 P10632 (/IDA) P33260 (/IDA) Q96SQ9 (/IDA)
Linoleic acid metabolic process GO:0043651
The chemical reactions and pathways involving linoleic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2.
3 Q6XVG2 (/IDA) Q91X77 (/IDA) Q9D816 (/IDA)
Oxidative demethylation GO:0070989
The process of removing one or more methyl groups from a molecule, involving the oxidation (i.e. electron loss) of one or more atoms in the substrate.
3 P10632 (/IDA) P11712 (/IDA) P11712 (/IDA)
Xenobiotic metabolic process GO:0006805
The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to living organisms. Used of chemical compounds, e.g. a xenobiotic chemical, such as a pesticide.
2 P12791 (/ISO) Q05421 (/ISO)
Steroid metabolic process GO:0008202
The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.
2 P12791 (/ISO) Q05421 (/ISO)
Response to bacterium GO:0009617
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.
2 P12791 (/IEP) Q05421 (/IEP)
Coumarin metabolic process GO:0009804
The chemical reactions and pathways involving coumarins, compounds derived from the phenylacrylic skeleton of cinnamic acids.
2 P11509 (/IDA) P11711 (/IDA)
Coumarin metabolic process GO:0009804
The chemical reactions and pathways involving coumarins, compounds derived from the phenylacrylic skeleton of cinnamic acids.
2 P11509 (/TAS) Q16696 (/TAS)
Response to metal ion GO:0010038
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus.
2 P00176 (/IEP) P04167 (/IEP)
Response to organonitrogen compound GO:0010243
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond.
2 P05179 (/IEP) P05182 (/IEP)
Drug metabolic process GO:0017144
The chemical reactions and pathways involving a drug, a substance used in the diagnosis, treatment or prevention of a disease; as used here antibiotic substances (see antibiotic metabolism) are considered to be drugs, even if not used in medical or veterinary practice.
2 P12791 (/ISO) Q05421 (/ISO)
Drug metabolic process GO:0017144
The chemical reactions and pathways involving a drug, a substance used in the diagnosis, treatment or prevention of a disease; as used here antibiotic substances (see antibiotic metabolism) are considered to be drugs, even if not used in medical or veterinary practice.
2 P04167 (/TAS) P05181 (/TAS)
Naphthalene metabolic process GO:0018931
The chemical reactions and pathways involving naphthalene, a fused ring bicyclic aromatic hydrocarbon commonly found in crude oil and oil products. Naphthalene is familiar as the compound that gives mothballs their odor; it is used in the manufacture of plastics, dyes, solvents, and other chemicals, as well as being used as an antiseptic and insecticide.
2 O35293 (/IDA) P24903 (/IDA)
Urea metabolic process GO:0019627
The chemical reactions and pathways involving urea, the water soluble compound O=C-(NH2)2.
2 P11712 (/IDA) P11712 (/IDA)
Monocarboxylic acid metabolic process GO:0032787
The chemical reactions and pathways involving monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-).
2 P11712 (/IDA) P11712 (/IDA)
Drug catabolic process GO:0042737
The chemical reactions and pathways resulting in the breakdown of a drug, a substance used in the diagnosis, treatment or prevention of a disease.
2 P11712 (/IMP) P11712 (/IMP)
Cellular amide metabolic process GO:0043603
The chemical reactions and pathways involving an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group, as carried out by individual cells.
2 P11712 (/IDA) P11712 (/IDA)
Response to ethanol GO:0045471
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.
2 P05179 (/IEP) P05182 (/IEP)
Heterocycle metabolic process GO:0046483
The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).
2 P05181 (/IDA) P33261 (/IDA)
Lauric acid metabolic process GO:0048252
The chemical reactions and pathways involving lauric acid, a fatty acid with the formula CH3(CH2)10COOH. Derived from vegetable sources.
2 A0A060WM81 (/IMP) Q92088 (/IMP)
Response to calcium ion GO:0051592
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
2 P00176 (/IEP) P04167 (/IEP)
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
2 P12791 (/ISO) Q05421 (/ISO)
Hematopoietic progenitor cell differentiation GO:0002244
The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells.
1 Q5GLZ0 (/IGI)
Lipid hydroxylation GO:0002933
The covalent attachment of a hydroxyl group to one or more fatty acids in a lipid.
1 B5X2R4 (/ISS)
Organic acid metabolic process GO:0006082
The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage.
1 P10632 (/IDA)
Triglyceride metabolic process GO:0006641
The chemical reactions and pathways involving triglyceride, any triester of glycerol. The three fatty acid residues may all be the same or differ in any permutation. Triglycerides are important components of plant oils, animal fats and animal plasma lipoproteins.
1 P05182 (/IMP)
Triglyceride metabolic process GO:0006641
The chemical reactions and pathways involving triglyceride, any triester of glycerol. The three fatty acid residues may all be the same or differ in any permutation. Triglycerides are important components of plant oils, animal fats and animal plasma lipoproteins.
1 Q05421 (/ISO)
Icosanoid metabolic process GO:0006690
The chemical reactions and pathways involving icosanoids, any of a group of C20 polyunsaturated fatty acids.
1 Q96SQ9 (/IDA)
Prostaglandin metabolic process GO:0006693
The chemical reactions and pathways involving prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring due to the formation of a bond between two carbons of a fatty acid. They have a wide range of biological activities.
1 Q96SQ9 (/IDA)
Xenobiotic metabolic process GO:0006805
The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to living organisms. Used of chemical compounds, e.g. a xenobiotic chemical, such as a pesticide.
1 P20813 (/IDA)
Xenobiotic metabolic process GO:0006805
The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to living organisms. Used of chemical compounds, e.g. a xenobiotic chemical, such as a pesticide.
1 P05182 (/IMP)
Aging GO:0007568
A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700).
1 P04167 (/IEP)
Response to nutrient GO:0007584
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus.
1 P05179 (/IEP)
Steroid metabolic process GO:0008202
The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.
1 P10632 (/IDA)
Response to toxic substance GO:0009636
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus.
1 P33267 (/IMP)
Response to ozone GO:0010193
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ozone stimulus.
1 P05182 (/IEP)
Response to sulfur dioxide GO:0010477
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sulfur dioxide (SO2) stimulus.
1 P00176 (/IEP)
Monoterpenoid metabolic process GO:0016098
The chemical reactions and pathways involving monoterpenoid compounds, terpenoids having a C10 skeleton.
1 Q05421 (/ISO)
Drug metabolic process GO:0017144
The chemical reactions and pathways involving a drug, a substance used in the diagnosis, treatment or prevention of a disease; as used here antibiotic substances (see antibiotic metabolism) are considered to be drugs, even if not used in medical or veterinary practice.
1 P05178 (/NAS)
Carbon tetrachloride metabolic process GO:0018885
The chemical reactions and pathways involving carbon tetrachloride, a toxic, carcinogenic compound which is used as a general solvent in industrial degreasing operations. It is also used as grain fumigant and a chemical intermediate in the production of refrigerants.
1 P05181 (/TAS)
Benzene metabolic process GO:0018910
The chemical reactions and pathways involving benzene, C6H6, a volatile, very inflammable liquid, contained in the naphtha produced by the destructive distillation of coal, from which it is separated by fractional distillation.
1 P05181 (/TAS)
Naphthalene metabolic process GO:0018931
The chemical reactions and pathways involving naphthalene, a fused ring bicyclic aromatic hydrocarbon commonly found in crude oil and oil products. Naphthalene is familiar as the compound that gives mothballs their odor; it is used in the manufacture of plastics, dyes, solvents, and other chemicals, as well as being used as an antiseptic and insecticide.
1 P33267 (/IMP)
Naphthalene metabolic process GO:0018931
The chemical reactions and pathways involving naphthalene, a fused ring bicyclic aromatic hydrocarbon commonly found in crude oil and oil products. Naphthalene is familiar as the compound that gives mothballs their odor; it is used in the manufacture of plastics, dyes, solvents, and other chemicals, as well as being used as an antiseptic and insecticide.
1 P33267 (/ISO)
Nicotine metabolic process GO:0018933
The chemical reactions and pathways involving nicotine, (S)(-)-3-(1-methyl-2-pyrrolidinyl)pyridine.
1 P04167 (/IEP)
4-nitrophenol metabolic process GO:0018960
The chemical reactions and pathways involving 4-nitrophenol, a nitroaromatic compound which is used in the production of dyes, leather treatment agents, fungicides and as an intermediate in the production of the insecticide parathion.
1 P05181 (/IDA)
Trichloroethylene metabolic process GO:0018979
The chemical reactions and pathways involving trichloroethylene, a toxic, colorless, photoreactive, chlorinated hydrocarbon liquid, commonly used as a metal degreaser and solvent.
1 O35293 (/IDA)
Trichloroethylene metabolic process GO:0018979
The chemical reactions and pathways involving trichloroethylene, a toxic, colorless, photoreactive, chlorinated hydrocarbon liquid, commonly used as a metal degreaser and solvent.
1 P33267 (/ISO)
Arachidonic acid metabolic process GO:0019369
The chemical reactions and pathways involving arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer.
1 P24470 (/NAS)
Response to lipopolysaccharide GO:0032496
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
1 P05179 (/IEP)
Response to retinoic acid GO:0032526
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus.
1 P05179 (/IEP)
Response to insulin GO:0032868
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
1 P00176 (/IEP)
Response to testosterone GO:0033574
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus.
1 P24470 (/IEP)
Heme metabolic process GO:0042168
The chemical reactions and pathways involving heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.
1 P20852 (/IDA)
Cellular ketone metabolic process GO:0042180
The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.
1 P20813 (/IDA)
Cellular ketone metabolic process GO:0042180
The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.
1 P12791 (/ISO)
Halogenated hydrocarbon metabolic process GO:0042197
The chemical reactions and pathways involving halogenated hydrocarbons, any hydrocarbon with one or more halogen atoms attached to it. Halogens include fluorine, chlorine, bromine and iodine.
1 P05181 (/TAS)
Exogenous drug catabolic process GO:0042738
The chemical reactions and pathways resulting in the breakdown of a drug that has originated externally to the cell or organism.
1 P12791 (/ISO)
Response to peptide hormone GO:0043434
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals.
1 P05179 (/IEP)
Coumarin catabolic process GO:0046226
The chemical reactions and pathways resulting in the breakdown of coumarins, compounds derived from the phenylacrylic skeleton of cinnamic acids.
1 P11509 (/IDA)
Heterocycle metabolic process GO:0046483
The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).
1 Q05421 (/ISO)
Lauric acid metabolic process GO:0048252
The chemical reactions and pathways involving lauric acid, a fatty acid with the formula CH3(CH2)10COOH. Derived from vegetable sources.
1 Q92088 (/IDA)
Lauric acid metabolic process GO:0048252
The chemical reactions and pathways involving lauric acid, a fatty acid with the formula CH3(CH2)10COOH. Derived from vegetable sources.
1 B5X2R4 (/ISS)
Cellular response to cadmium ion GO:0071276
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
1 P20852 (/IDA)

There are 23 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
21 A0A1D5RLI1 (/ISO) A6H6J2 (/ISO) E9Q5K4 (/ISO) O55071 (/ISO) P12790 (/ISO) P12791 (/ISO) P33267 (/ISO) P56655 (/ISO) P56656 (/ISO) Q05421 (/ISO)
(11 more)
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
12 D4A820 (/IDA) P00176 (/IDA) P04167 (/IDA) P05179 (/IDA) P05182 (/IDA) P11711 (/IDA) P11712 (/IDA) P11712 (/IDA) P13107 (/IDA) P24470 (/IDA)
(2 more)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
11 P05181 (/TAS) P10632 (/TAS) P11509 (/TAS) P11712 (/TAS) P11712 (/TAS) P20813 (/TAS) P24903 (/TAS) P33260 (/TAS) P33261 (/TAS) Q16696 (/TAS)
(1 more)
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
10 O18963 (/ISS) P05181 (/ISS) P08682 (/ISS) P33266 (/ISS) P51581 (/ISS) P51581 (/ISS) P79383 (/ISS) Q05421 (/ISS) Q6GUQ4 (/ISS) Q9MZY0 (/ISS)
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
3 P11712 (/TAS) P11712 (/TAS) P33261 (/TAS)
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
2 P00176 (/IDA) P05182 (/IDA)
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
2 P12791 (/ISO) Q05421 (/ISO)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
2 Q05421 (/IDA) Q96SQ9 (/IDA)
Cytoplasmic microtubule GO:0005881
Any microtubule in the cytoplasm of a cell.
2 P15392 (/ISO) P20852 (/ISO)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
2 A0A060WM81 (/IMP) Q92088 (/IMP)
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
2 P19225 (/NAS) P19225 (/NAS)
Golgi membrane GO:0000139
The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
1 P05182 (/IDA)
Golgi membrane GO:0000139
The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
1 Q05421 (/ISO)
Cell GO:0005623
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
1 H0ZA72 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 P05182 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q05421 (/ISO)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
1 Q9DBX6 (/ISO)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
1 P05182 (/IDA)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
1 Q05421 (/ISO)
Cytoplasmic microtubule GO:0005881
Any microtubule in the cytoplasm of a cell.
1 P11509 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 B5X2R4 (/ISS)
Intrinsic component of endoplasmic reticulum membrane GO:0031227
The component of the endoplasmic reticulum membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
1 P05182 (/IDA)
Intrinsic component of endoplasmic reticulum membrane GO:0031227
The component of the endoplasmic reticulum membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
1 Q05421 (/ISO)
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