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CATH Superfamily 1.10.620.20

Ribonucleotide Reductase, subunit A

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Ribonucleotide Reductase, subunit A
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Ribonucleoside-diphosphate reductase 1 subunit bet...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Iron ion binding GO:0005506
Interacting selectively and non-covalently with iron (Fe) ions.
 61 P69924 (/IDA) P69924 (/IDA) P69924 (/IDA) P69924 (/IDA) P69924 (/IDA) P69924 (/IDA) P69924 (/IDA) P69924 (/IDA) P69924 (/IDA) P69924 (/IDA)
(51 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 61 P69924 (/IPI) P69924 (/IPI) P69924 (/IPI) P69924 (/IPI) P69924 (/IPI) P69924 (/IPI) P69924 (/IPI) P69924 (/IPI) P69924 (/IPI) P69924 (/IPI)
(51 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
 61 P69924 (/IPI) P69924 (/IPI) P69924 (/IPI) P69924 (/IPI) P69924 (/IPI) P69924 (/IPI) P69924 (/IPI) P69924 (/IPI) P69924 (/IPI) P69924 (/IPI)
(51 more)
Ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor GO:0004748
Catalysis of the reaction: 2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin.
 5 Q9KSK1 (/ISS) Q9KSK1 (/ISS) Q9KSK1 (/ISS) Q9KSK1 (/ISS) Q9KSK1 (/ISS)
Ribonucleoside binding GO:0032549
Interacting selectively and non-covalently with a ribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to ribose.
 2 A0A023ZUP0 (/IDA) A0A023ZUP0 (/IDA)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Deoxyribonucleotide biosynthetic process GO:0009263
The chemical reactions and pathways resulting in the formation of a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
 61 P69924 (/IDA) P69924 (/IDA) P69924 (/IDA) P69924 (/IDA) P69924 (/IDA) P69924 (/IDA) P69924 (/IDA) P69924 (/IDA) P69924 (/IDA) P69924 (/IDA)
(51 more)
Nucleobase-containing small molecule interconversion GO:0015949
The chemical reactions and pathways by which a nucleobase, nucleoside or nucleotide small molecule is synthesized from another nucleobase, nucleoside or nucleotide small molecule.
 61 P69924 (/IDA) P69924 (/IDA) P69924 (/IDA) P69924 (/IDA) P69924 (/IDA) P69924 (/IDA) P69924 (/IDA) P69924 (/IDA) P69924 (/IDA) P69924 (/IDA)
(51 more)
2'-deoxyribonucleotide biosynthetic process GO:0009265
The chemical reactions and pathways resulting in the formation of a 2'-deoxyribonucleotide, a compound consisting of 2'-deoxyribonucleoside (a base linked to a 2'-deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
 5 Q9KSK1 (/ISS) Q9KSK1 (/ISS) Q9KSK1 (/ISS) Q9KSK1 (/ISS) Q9KSK1 (/ISS)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
 61 P69924 (/IDA) P69924 (/IDA) P69924 (/IDA) P69924 (/IDA) P69924 (/IDA) P69924 (/IDA) P69924 (/IDA) P69924 (/IDA) P69924 (/IDA) P69924 (/IDA)
(51 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 61 P69924 (/HDA) P69924 (/HDA) P69924 (/HDA) P69924 (/HDA) P69924 (/HDA) P69924 (/HDA) P69924 (/HDA) P69924 (/HDA) P69924 (/HDA) P69924 (/HDA)
(51 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 61 P69924 (/IDA) P69924 (/IDA) P69924 (/IDA) P69924 (/IDA) P69924 (/IDA) P69924 (/IDA) P69924 (/IDA) P69924 (/IDA) P69924 (/IDA) P69924 (/IDA)
(51 more)
Ribonucleoside-diphosphate reductase complex GO:0005971
An enzyme complex composed of 2-4 or more subunits, which usually contains nonheme iron and requires ATP for catalysis. Catalyzes the formation of 2'-deoxyribonucleoside diphosphate from ribonucleoside diphosphate, using either thioredoxin disulfide or glutaredoxin disulfide as an acceptor.
 61 P69924 (/IDA) P69924 (/IDA) P69924 (/IDA) P69924 (/IDA) P69924 (/IDA) P69924 (/IDA) P69924 (/IDA) P69924 (/IDA) P69924 (/IDA) P69924 (/IDA)
(51 more)