View in Gene3D

CATH Superfamily 1.10.600.10

Farnesyl Diphosphate Synthase

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Farnesyl Diphosphate Synthase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 36: cis-abienol synthase, chloroplastic

There are 5 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Beta-phellandrene synthase (neryl-diphosphate-cyclizing). [EC: 4.2.3.51]
Neryl diphosphate = beta-phellandrene + diphosphate.
  • The enzyme from Solanum lycopersicum has very poor affinity with geranyl diphosphate as substrate.
  • Catalyzes the formation of the acyclic myrcene and ocimene as major products in addition to beta-phellandrene.
 4 C1K5M3 C1K5M3 R9R6F4 R9R6F4
Geranyllinalool synthase. [EC: 4.2.3.144]
Geranylgeranyl diphosphate + H(2)O = (E,E)-geranyllinalool + diphosphate.
  • The enzyme is a component of the herbivore-induced indirect defense system.
  • The product, (E,E)-geranyllinalool, is a precursor to the volatile compound 4,8,12-trimethyl-1,3,7,11-tridecatetraene (TMTT), which is released by many plants in response to damage.
 1 Q93YV0
Cis-abienol synthase. [EC: 4.2.3.140]
(13E)-8-alpha-hydroxylabd-13-en-15-yl diphosphate = cis-abienol + diphosphate.
  • Isolated from the plants Abies balsamea (balsam fir) and Nicotiana tabacum (tobacco).
 1 G3CCC1
Miltiradiene synthase. [EC: 4.2.3.131]
(+)-copalyl diphosphate = miltiradiene + diphosphate.
  • Isolated from the plants Rosmarinus officinalis (rosemary) and Salvia miltiorrhiza.
  • The enzyme from the plant Selaginella moellendorffii is mutifunctional and also catalyzes EC 5.5.1.12.
 1 G9MAN7
Copalyl diphosphate synthase. [EC: 5.5.1.12]
Geranylgeranyl diphosphate = (+)-copalyl diphosphate.
  • In some plants, such as Salvia miltiorrhiza, this enzyme is monofunctional.
  • In other plants this activity is often a part of a bifunctional enzyme.
  • For example, in Selaginella moellendorffii this activity is catalyzed by a bifunctional enzyme that also catalyzes EC 4.2.3.131, while in the tree Abies grandis (grand fir) it is catalyzed by a bifunctional enzyme that also catalyzes EC 4.2.3.18.
 1 G9MAN7
CATH-Gene3D is a Global Biodata Core Resource Learn more...